Synthetic Peptides
Identification, using synthetic peptides, of the minimum amino acid sequence from the retroviral transmembrane protein p15E required for inhibition of lymphoproliferation and its similarity to gp21 of human T-lymphotropic virus types I and II.
... To substantiate the physiological relevance of the inhibition of lymphoproliferation observed with the synthetic peptides and to relate this activity to the intact protein, we purified t[r] ...
7
Cooperative effects in differentiation and proliferation between PDGF BB and matrix derived synthetic peptides in human osteoblasts
... Recently, synthetic peptides like AC- 100, TP508 or p-15 corresponding to biologically active sequences of matrix proteins have been proven to stimulate bone ...with synthetic peptides could ...
7
EVALUATION OF THE GROWTH PROMOTING POTENCY OF 6 DIFFERENT SYNTHETIC PEPTIDES USING RAMA 27 CELL LINE
... six peptides, produced higher cpm for P2 and P4 ...the synthetic 9 folds of the peptide ...six synthetic peptides with. Equal volume mixture of SNP and synthetic peptides showed ...
15
Analysis of the role of antibody dependent cellular cytotoxic antibody activity in murine neonatal herpes simplex virus infection with antibodies to synthetic peptides of glycoprotein D and monoclonal antibodies to glycoprotein B
... against synthetic peptides of predicted epitopes of HSV glycoprotein D (gD) were used to determine in vitro functional activity and association with protection against lethal infection in a murine model of ...
7
Inhibition of lymphoproliferation and protein kinase C by synthetic peptides with sequence identity to the transmembrane and Q proteins of visna virus.
... Identification, using synthetic peptides, of the minimum amino acid sequence from the retroviral transmembrane protein plSE required for inhibition of lymphoproliferation and its similar[r] ...
6
Inhibition of human immunodeficiency virus type 1 infection and syncytium formation in human cells by V3 loop synthetic peptides from gp120.
... We examined the effects of synthetic peptides from the V3 loop regions of different HIV-1 strains and observed that peptides of 8 to 15 amino acids exhibit efficient inhibition of virus [r] ...
6
Abstract: After screening nearly 1000 synthetic peptides, a synthetic peptide termed JAL-AK22
... Identification of auto-proteolysis activity of JAL-AK22 (a) time dependent 83.. analysis (b) peak collection 84.[r] ...
17
Peptide Impurities in Commercial Synthetic Peptides and Their Implications for Vaccine Trial Assessment
... overlapping peptides have revolutionized the fields of vaccine efficacy testing and cellular immune response ...stimulating peptides, assurance of high-quality and reliable input peptides is an ...
10
Human cytomegalovirus structural proteins: immune reaction against pp150 synthetic peptides
... The sequences of the peptides to be synthesized were decided on the basis of either their presence in the DI fusion protein 6, 12, already known to be frequently recognized by human anti[r] ...
5
Antibody responses to synthetic peptides from cytomegalovirus phosphoprotein 150
... All convalescent-phase serum samples from 26 patients with active CMV infection reacted with either of two peptides encompassing amino acids aa 594 to 623 and aa 614 to 643.. Patients wi[r] ...
5
A New Generation of Drugs: Synthetic Peptides Based on Natural Regulatory Peptides
... The Bcl6 gene, which encodes a nuclear sequence- specific transcriptional repressor that plays a key role in the formation and development of the immune system, exhibited significant changes in its expression levels in ...
30
Detection of human antibodies against Plasmodium falciparum sporozoites using synthetic peptides
... falciparum circumsporozoite protein can be used for the detection of antisporozoite antibodies and for the epidemiological studies required to obtain base-line data concerning the immune[r] ...
6
Lipid membrane fusion induced by the human immunodeficiency virus type 1 gp41 N-terminal extremity is determined by its orientation in the lipid bilayer.
... formation. Peptides with sequences taken from the human immunodeficiency virus type 1 gp41 fusogenic (synthetic peptides SPwt and SP-2) and nonfusogenic (SP-3 and SP-4) glycoproteins adopt mainly a b ...
7
Synthetic Aβ peptides acquire prion-like properties in the brain
... Aβ peptides in supernatants (S2) and pellets (P2) were determined by western ...two synthetic peptides were treated with PK (concentration ranging between 0 and 50 µg/ml) to investigate their ...
9
Synthetic amphipathic helical peptides that mimic apolipoprotein A I in clearing cellular cholesterol
... helical peptides also competed for high-affinity HDL binding sites on cholesterol-loaded fibroblasts and displayed saturable high-affinity binding to the cell ...contrast, peptides with a single helix had ...
9
A large-scale evaluation of peptide vaccines against foot-and-mouth disease: lack of solid protection in cattle and isolation of escape mutants.
... a synthetic vaccine, the lower the chances of its affording solid protection against natural isolates of viruses (10, 26, 29, ...FMD peptides were carried out with lim- ited numbers of animals, and the ...
9
Localization of a domain in the FimH adhesin of Escherichia coli type 1 fimbriae capable of receptor recognition and use of a domain specific antibody to confer protection against experimental urinary tract infection
... at synthetic peptides corresponding to epitopes within the binding domain could specifically block type 1 fimbriae-mediated bacterial adherence to bladder epithelial cells in situ and yeast cells in ...
15
Multiantigen Print Immunoassay for Comparison of Diagnostic Antigens for Taenia solium Cysticercosis and Taeniasis
... Taenia solium antigens. Recombinant proteins rGP50, rES33, and rES38 were expressed in Sf21/Sf9 cells by using a baculovirus system. Similarly, the extracel- lular domain of T24, rT24H, was expressed in Tni cells (8, 9, ...
5
Antigenic Domains of the Open Reading Frame 2 Encoded Protein of Hepatitis E Virus
... used synthetic peptides (9, 18–20) or recom- binant proteins (24, 25, 43) to identify antigenic epitopes within the HEV ORF2-encoded ...of synthetic peptides derived from this region, however, ...
9
Mutations in human immunodeficiency virus type 1 gp41 affect sensitivity to neutralization by gp120 antibodies.
... Emergence of viruses resistant to neutralization by V3-specific antibodies in experimental human immunodeficiency virus type 1 IIIB infection of chimpanzees.. Synthetic peptides and anti[r] ...
6