Systemic immunity
H9N2 Influenza Whole Inactivated Virus Combined with Polyethyleneimine Strongly Enhances Mucosal and Systemic Immunity after Intranasal Immunization in Mice
... Here, we demonstrated that PEI as a potent mucosal adjuvant also effectively combined with H9N2 WIV and elicited robust local and systemic immunity compared with CTB. These data con- firmed that the ...
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Effects of different forms of yeast Saccharomyces cerevisiae on growth performance, intestinal development, and systemic immunity in early-weaned piglets
... and systemic immunity in early-weaned piglets, with better improvement in feed conversion by dietary supplementation with LY, while dietary supplementation with SFY was more effective in increasing ...
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In feed supplementation of clinoptilolite favourably modulates intestinal and systemic immunity and some production parameters in weaned pigs
... on systemic immunity related to either general immune-enhancing activity which rein- forces the clearance of porcine circovirus type 2 in ex- perimentally infected weaned pigs (Jung et ...of systemic ...
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Systemic immunity shapes the oral microbiome and susceptibility to bisphosphonate associated osteonecrosis of the jaw
... the systemic expression levels of these genes, and it supports a role for AHR in maintaining oral barrier function in humans, as was found to be the case for the murine gut ...
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Sex impacts Th1 cells, Tregs, and DCs in both intestinal and systemic immunity in a mouse strain and location-dependent manner
... for systemic differences [3, 4], in general, we found that the innate immune arm (DCs, macrophages, and NK cells) of the PP was enhanced in males as compared with females, as measured by per- centage of cells and ...
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Systemic Immunity and Mucosal Immunity Are Induced against Human Immunodeficiency Virus Gag Protein in Mice by a New Hyperattenuated Strain of Listeria monocytogenes
... cell-mediated immunity plays an essential role in controlling human immunodeficiency virus (HIV) infection (12, 38), although efforts to develop an effec- tive vaccine for HIV have been ...
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A retrospective study of factors associated with treatment decision for nontuberculous mycobacterial lung disease in adults without altered systemic immunity
... acquired systemic immune deficiency such as defects in the pathways of in- flammatory cytokines interleukin (IL)-12, tumor necrosis factor (TNF)- α or interferon (IFN)- γ , immunosuppres- sive treatments ...
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Buccal and sublingual vaccine delivery
... adaptive immunity or tolerance, and whether there exist germinal centers in oral lymphoid foci are discussed exten- sively by others ...mucosal immunity, as well as systemic immunity, against ...
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Anti–PD 1/PD L1 therapy of human cancer: past, present, and future
... site at which anti-PD therapy predominately takes place. In the context of a broadly inducible pattern of PD-L1 expression by IFN-γ, it will not be a surprise to see the expression of PD-L1 on tumor cells, tumor stromal ...
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Immunomodulation after ischemic stroke: potential mechanisms and implications for therapy
... and systemic effects. Suppression of systemic immunity by the nervous system could protect the brain from additional inflammatory damage; however, it may increase the susceptibility to ...
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Prevention of Hearing Loss by Alteration of the Systemic Immune System
... the systemic immunity and cochlea, indicating that reconstruction of recipient immune system can treat SHL as a cochlear disorder; 2) This study demonstrate that in- flammaging promoted aging and AHL; 3) ...
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The Contribution of Systemic and Pulmonary Immune Effectors to Vaccine-Induced Protection from H5N1 Influenza Virus Infection
... pulmonary immunity in the lungs of mice is determined by local replication of the vaccine virus ...pulmonary immunity on protective efficacy against wt virus challenge, because the corresponding H3N2 wt ...
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A Multicomponent Vaccine Provides Immunity against Local and Systemic Infections by Group A Streptococcus across Serotypes
... IMPORTANCE GAS is among the most common human pathogens and causes a wide variety of diseases, likely more than any other microorganism. The diverse clini- cal manifestations of GAS may be attributable to its large ...
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Induction of systemic and mucosal immunity against methicillin-resistant <em>Staphylococcus aureus</em> infection by a novel nanoemulsion adjuvant vaccine
... We observed that the IgG levels of serum following the intramuscular or nasal mucosal immune response were higher than those generated in response to the naive antigen vac- cine. Moreover, the nasal and intramuscular ...
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Enhanced Influenza Virus-Like Particle Vaccines Containing the Extracellular Domain of Matrix Protein 2 and a Toll-Like Receptor Ligand
... protective immunity compared to other routes ...high systemic immune responses as well as strong mucosal immunity and confers more effective protection against live virus challenge, as demonstrated ...
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Mucosal and systemic anti HIV immunity controlled by A20 in mouse dendritic cells
... and systemic immune responses are required for preventing or containing HIV transmission and chronic ...and systemic HIV-specific cellular and humoral ...robust systemic and mucosal anti-HIV cellular ...
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High-Capacity Adenovirus Vector-Mediated Anti-Glioma Gene Therapy in the Presence of Systemic Antiadenovirus Immunity
... FIG. 3. HC-Ads and Ads mediate high levels of short-term HSV-1 TK expression in preimmunized non-tumor-bearing animals with minimal inflammation at 1 week after vector delivery. Animals were preimmunized with a ...
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Development of mucosal and systemic lymphoproliferative responses and protective immunity to human group A rotaviruses in a gnotobiotic pig model.
... Using the gnotobiotic pig model, we compared inoculations with live attenuated and virulent human rotavirus followed by homologous virulent virus challenge to identify cellular corre- lates of protective immunity. ...
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Maternal HIV-1 Env Vaccination for Systemic and Breast Milk Immunity To Prevent Oral SHIV Acquisition in Infant Macaques
... Both systemic and mucosal immu- nization strategies elicited similar levels of HIV-1 Env-specific IgG in milk and plasma, but the mucosal immunization induced a higher magnitude Env-specific IgA response in ...
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Distinct Roles of Vaccinia Virus NF-κB Inhibitor Proteins A52, B15, and K7 in the Immune Response
... in immunity, we deleted their genes in an NYVAC (New York vaccinia virus) strain that expresses HIV-1 clade C ...humoral immunity, and their ablation offers alternatives for de- sign of vaccine vectors that ...
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