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Systemic Lupus Erythematous.

Original Article Down-regulation of nectin-4 inhibits apoptosis in systemic lupus erythematous (SLE) through targeting Bcl-2/Bax pathway

Original Article Down-regulation of nectin-4 inhibits apoptosis in systemic lupus erythematous (SLE) through targeting Bcl-2/Bax pathway

... Systemic lupus erythematous (SLE), an organ- specific autoimmune disease, which is charac- terized by the abnormal activation of self-reac- tive T and B cells and self-antibodies and immune complex ...

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A Study on Pulmonary Manifestations in Systemic Lupus Erythematous

A Study on Pulmonary Manifestations in Systemic Lupus Erythematous

... This is to certify that the dissertation entitled “ A STUDY ON PULMONARY MANIFESTATIONS IN SYSTEMIC LUPUS ERYTHEMATOUS ” is a bonafide work done by DR. Y.N.NARAYANASWAMY, Post Graduate Student, ...

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Call for Vigilance – Red Flags in Systemic Lupus Erythematous

Call for Vigilance – Red Flags in Systemic Lupus Erythematous

... Systemic lupus erythematous (SLE) is an autoimmune disease affecting multiple ...of systemic lupus erythematous is reported between 20-150 cases per ...

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A rare presentation of toxoplasma encephalitis in systemic lupus erythematous patient: case report and review of literature

A rare presentation of toxoplasma encephalitis in systemic lupus erythematous patient: case report and review of literature

... complicating systemic lupus erythematous (SLE) have been reported in the medical literature, and this emphasizes the difficulty in establishing the diagnosis, because of most report confirmed the ...

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High sensitivity cardiac troponin T is a biomarker for atherosclerosis in systemic lupus erythematous patients: a cross sectional controlled study

High sensitivity cardiac troponin T is a biomarker for atherosclerosis in systemic lupus erythematous patients: a cross sectional controlled study

... in Lupus Erythe- matosus National Assessment (SELENA)-Systemic Lupus Erythematosus Disease Activity Index (SLEDAI) score ...[12]. Lupus nephritis diagnosis was based on Inter- national Society ...

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Biomarkers associating endothelial Dysregulation in pediatric-onset systemic lupus erythematous

Biomarkers associating endothelial Dysregulation in pediatric-onset systemic lupus erythematous

... Vascular endothelial growth factor (VEGF), a member of the angiogenic factor superfamily, also known as vascu- lar permeability factor, is both a potent enhancer of microvascular permeability and a selective endothelial ...

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SYSTEMIC LUPUS ERYTHEMATOSUS

SYSTEMIC LUPUS ERYTHEMATOSUS

... Systemic lupus Erythematous is a multi-system inflammatory disorder characterised by auto antibody production and other immune system abnormalities. The hall mark of SLE is the development of auto- ...

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Successful use of Ustekinumab in a Patient with Psoriasis,
Psoriatic Arthritis and Systemic Lupus Erythematosus: A Case
report and Review of literature

Successful use of Ustekinumab in a Patient with Psoriasis, Psoriatic Arthritis and Systemic Lupus Erythematosus: A Case report and Review of literature

... of systemic lupus erythematous (SLE) ...cutaneous lupus (non SLE), suggesting that targeting the TH-17 pathway may be useful in this condition, its use in SLE remains poorly described ...

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Kikuchi's Disease With Multisystemic Involvement and Adverse Reaction to Drugs

Kikuchi's Disease With Multisystemic Involvement and Adverse Reaction to Drugs

... methods yielded the same information. The charac- teristic histopathologic features of the disease are 1) focal necrosis, predominantly in the paracortical re- gion with abundant karyorrhexis; 2) aggregates of atypical ...

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Intestinal Dysbiosis Associated with Systemic Lupus Erythematosus

Intestinal Dysbiosis Associated with Systemic Lupus Erythematosus

... Systemic lupus erythematous (SLE) is a prototypical autoim- mune disease in humans that is characterized by the presence of hyperactive immune cells and aberrant antibody responses to nu- clear and ...

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Mortality Patterns in Malaysian Systemic Lupus Erythematosus Patients

Mortality Patterns in Malaysian Systemic Lupus Erythematosus Patients

... Mortality Patterns in Malaysian Systemic Lupus Erythematosus Patients ORIGINAL ARTICLE Mortality Patterns in Malaysian Systemic Lupus Erythematosus Patient~ S S Yeap, MRCP*, S K Chow, MRCP*, M Manivas[.] ...

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A Study of Prevalence of Metabolic Syndrome in Patients of Psoriasis of North India

A Study of Prevalence of Metabolic Syndrome in Patients of Psoriasis of North India

... concentration of Apo A-1. These lipid abnormalities seen in psoriatic patients, while promoting atherosclerosis, might in parallel facilitate and maintain the systemic inflammatory reaction predisposing to MS. ...

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Risk factors for damage in childhood-onset systemic lupus erythematosus in Asians: a case control study

Risk factors for damage in childhood-onset systemic lupus erythematosus in Asians: a case control study

... Clinical variables between the two patient groups, ‘ no disease damage ’ (SDI = 0) and ‘ disease damage present ’ (SDI ≥ 1), were compared first using univariate analysis. Disease damage was significantly associated with ...

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Complement and systemic lupus erythematosus

Complement and systemic lupus erythematosus

... of lupus- like autoimmunity [157,158], which provides further evidence that complement-deficient mice are a useful model to study the association between complement deficiency and SLE, first described in ...

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Suppression of lupus nephritis and skin lesions in MRL/lpr mice by administration of the topoisomerase I inhibitor irinotecan

Suppression of lupus nephritis and skin lesions in MRL/lpr mice by administration of the topoisomerase I inhibitor irinotecan

... of lupus-associated glomerulonephritis and pre- vented the onset of skin ...inhibiting lupus nephritis than skin ...both lupus nephritis and skin lesions in MRL/lpr ...

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Ocular Manifestations of Systemic Lupus Erythematosus and Systemic Lupus Erythematosus with Antiphospholipid Syndrome.

Ocular Manifestations of Systemic Lupus Erythematosus and Systemic Lupus Erythematosus with Antiphospholipid Syndrome.

... Ophthalmic side effects and disease can also result from the medications used to treat SLE. Both topical and systemic corticosteroids may accelerate cataract formation and may cause steroid-induced glaucoma. ...

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Spectrum of paediatric rheumatic diseases in Nigeria

Spectrum of paediatric rheumatic diseases in Nigeria

... juvenile lupus or all CTDs was the next in their reports [12, 16, ...19]. Systemic vasculitis was the com- monest PRD observed in Singapore by Tan et ...any systemic vasculitis in our series [3, ...

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Serum Vascular Endothelial Growth Factor
(VEGF) as a Biomarker for Disease Activity in
Lupus Nephritis

Serum Vascular Endothelial Growth Factor (VEGF) as a Biomarker for Disease Activity in Lupus Nephritis

... with lupus nephritis and those with non-LN ...(8). Lupus nephritis patients were defined as those who fulfilled the ACR diagnostic criteria for LN ...with systemic sepsis, malignancy, diabetes ...

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Systemic lupus erythematosus and fractures

Systemic lupus erythematosus and fractures

... with lupus, no in fl u- ence of HCQ use on bone mass was ...with lupus (since this drug is currently regarded as an ‘ anchor drug ’ for SLE therapy), further research on the in fl uence of antimalarials on ...

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Systemic Lupus Erythematosus: A Review

Systemic Lupus Erythematosus: A Review

... of lupus nephritis, but it is not FDA-approved for this indication, and FDA is investigating reports that it may be associated with birth defects when used by pregnant ...

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