Systems Medicine
Radiomics and liquid biopsy in oncology: the holons of systems medicine
... Radiomics is a process of extraction and analysis of quantitative features from diagnostic images. Liquid biopsy is a test done on a sample of blood to look for cancer cells or for pieces of tumourigenic DNA circulating ...
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Systems medicine advances in interstitial lung disease
... 2]. Systems biology is a biology-based interdisciplinary area that studies complex interactions within biological systems, using a holistic approach to biological ...populations. Systems ...
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Clinical decision-making and secondary findings in systems medicine
... of systems medicine is the generation of statistically-based clin- ical predictions, predictions that promise to inform clinicians of what is likely to happen, even if they can cast no light on the question ...
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Applying systems biology to biomedical research and health care: a précising definition of systems medicine
... of Systems Medicine is used as an empty phrase, which is presumably why it has not been taken into consideration by which means the end of (improving) participation could be ...of Systems Medi- cine ...
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Systems medicine: the future of medical genomics and healthcare
... of systems approaches for deciphering the functional and regulatory networks underlying the behavior of complex biological ...Iterative systems approaches are starting to provide deeper insights into the ...
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Integrative systems medicine approaches to identify molecular targets in lymphoid malignancies
... Abbreviations DLBCL: diffuse large B cell lymphoma; FL: follicular lymphoma; CLL: chronic lymphocytic leukemia; SLL: small lymphocytic lymphoma; SM: systems medicine; WGS: whole genome s[r] ...
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Systems Medicine: from molecular features and models to the clinic in COPD
... Network approaches to human disease are based on the observation that the cellular components associated with a specific disease are not scattered randomly within the Interactome, but segregate in certain neighborhoods ...
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Modules, networks and systems medicine for understanding disease and aiding diagnosis
... Systems medicine is an emerging discipline that aims to address the problem that a disease is rarely caused by malfunction of one individual gene product, but instead depends on multiple gene products that ...
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Computational dynamic approaches for temporal omics data with applications to systems medicine
... dynamic systems and simultaneously estimating the kinetic structural and functional parameters are extremely important in systems and computational ...biological systems are essentials to discover ...
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Systems medicine and integrated care to combat chronic noncommunicable diseases
... level systems approaches to tackle NCDs as a common group of ...(P4) medicine based on a robust and extensive knowledge management infrastructure that contains individual patient ...This systems ...
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Systems medicine and the integration of bioinformatic tools for the diagnosis of Alzheimer's disease
... a systems approach to study AD will demand integration of heterogeneous data (such as molecular and image data) and studies of disease-associated molecules and their assemblies beyond the pathway-centric ...
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Systems medicine and integrated care for pulmonary rehabilitation. E.F.M. Wouters Department of Respiratory Medicine Maastricht University
... Outcome assessment.. Bewee g gedrag in dagelij kse praktij k Bewee g gedrag in dagelij kse praktij k Fysiek e fitheid Fysiek e fitheid Dispn eu manag ement basis Dispn eu man[r] ...
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Systems medicine and infection
... health systems in high HIV prevalence settings, uncertainty in the natural progression of TB-HIV and combined interventions for ...a systems based approach, where modellers’ and key stakeholders’ ...
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StemCellMathLab Systems Medicine of Leukemia
... • What are current open questions in understanding basic biological principles that underlie hematological malignancies and how can these be addressed by mathematical models?. • Whi[r] ...
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Bridging the gap between systems biology and medicine
... in systems biology and clinically useful results are only now becoming ...of systems medicine is emerging as a translational extension of systems ...is systems medicine defined? ...
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From systems biology to P4 medicine: applications in respiratory medicine
... informational power can be augmented ( “ integrated ” ) with additional molecular interactions available from public sources with the help of dedicated software (e.g. Cytoscape plugins [65] for the STRING protein – ...
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Systems and precision medicine approaches to diabetes heterogeneity: a Big Data perspective
... within systems medicine ...biological systems, the potential of emerging diagnostic tools and therapeutic functions can be ultimately ...Precision Medicine by allowing an increasing number of ...
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Integrative systems of genomic risk markers for cancer and other diseases: future of predictive medicine
... Abstract: This paper focuses on genomic predictive biomarkers in medicine. It is known that single nucleotide polymorphisms of genes involved in the pathogenesis of various diseases, including cancer, can serve as ...
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A novel systems pharmacology model for herbal medicine injection: a case using reduning injection
... (3) systems analysis for the action mechanisms of Reduning; and (4) the experimental veri- ...this systems pharmacology model may reveal the power of the combined approach for screening bio- active ...
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Assessment of disease severity scoring systems for patients with sepsis in general internal medicine departments
... Only a few scoring systems exist that are not restricted to a specific medical condition or ICU setting. The Modified Early Warning Score (MEWS) is a simple physiological scoring system suitable for bedside ...
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