T-cell Epitopes
Identification of Hexon-Specific CD4 and CD8 T-Cell Epitopes for Vaccine and Immunotherapy
... adenovirus-specific T cells may prevent and treat such infections, the T-cell immune response to the multiplicity of adenovirus serotypes and subspecies that infect humans has not been well ...
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IN SILICO HOMOLOGY STRUCTURE, B CELL AND T CELL EPITOPES PREDICTION OF SERINE/THREONINE PROTEIN KINASE A AGAINST TUBERCULOSIS
... B-cell epitopes having BCPred score > ...of T-cell by using MHCPred. Common epitopes that bind to both MHC classes were found out on the basis of their IC50 value for the particular ...
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Identification of Cross-Reactive Norovirus CD4+ T Cell Epitopes
... that T cell epitopes are conserved within the ...memory T cell response upon subse- quent challenge with genetically related ...some epitopes may be evolving over time in geno- ...
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HLA A*0201 restricted CD8+T cell epitopes identified in dengue viruses
... Based on the amino acid sequence of D1V (Hawaii strain; GenBank Accession No: ACF49259), the epi- tope prediction algorithms SYFPEITHI with PAProc (http://www.syfpeithi.de; http://www.paproc.de) were applied to predict ...
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The generation of cytotoxic T cell epitopes and their generation for cancer immunotherapy
... immunodominant epitopes more than sub- dominant T cell epitopes, which is a reason why the latter category of epitopes in these differentiation antigens has attracted consider- able ...
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Identification and localization of minimal MHC-restricted CD8+ T cell epitopes within the Plasmodium falciparum AMA1 protein
... variable epitopes[24] including one site that is also recognized by a putative receptor for AMA1 binding to red blood ...important T cell epitopes of AMA1, and whether or not they fall in the ...
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Original Article Analysis of T-cell epitopes of Der f3 in Dermatophagoides farina
... its T-cell epitopes fail to be determined to date, since allergen spe- cific immunotherapy (SIT) is generally recog- nized as the only gene therapy for this entity via desensitization for the ...
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In silico Identification of novel B Cell and T cell epitopes of Wuhan coronavirus (2019-
... bioinformatics analysis was used to predict B cell and T cell epitopes of surface glycoprotein of 46.. 2019-nCoV that could be suitable to trigger significant immune response.[r] ...
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Cross reactive human B cell and T cell epitopes between influenza A and B viruses
... + T cell epitopes conserved between the two genera were identified in ...+ T cell epitope was located in the fusion peptide of the ...antibody epitopes in humans and ...the ...
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Why Are CD8 T Cell Epitopes of Human Influenza A Virus Conserved?
... CD8 T cell epitopes of human IAV are ...universal T cell-inducing vaccines against influenza and whether the virus is likely to evolve to escape the vaccine-induced ...CD8 T ...
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Prediction of T cell epitopes of hepatitis C virus genotype 5a
... HCV epitopes focused mainly on genotype 1 [41,42], but most of these studies do not take into account the diversity in other genotypes that are common in developing countries like most African ...antigenic ...
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Differential Antigen Presentation Kinetics of CD8+ T-Cell Epitopes Derived from the Same Viral Protein
... ⫹ T cells, and percentages of tumor necrosis factor alpha (TNF- ␣ )- and gamma interferon (IFN- ␥ )-positive cells are ...⫹ T cells responded to infected CD4 ⫹ T cells that were MHC-I mismatched ...
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Identification of T-Cell Epitopes in Nonstructural Proteins of Foot-and-Mouth Disease Virus
... of T-cell epitopes conserved among FMDV serotypes, which are consistently recognized by lymphocytes from domestic ...of T-cell epitopes in 3A, 3B, and ...the T-cell ...
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Immunodominant T-Cell Epitopes in the VP1 Capsid Protein of Rhinovirus Species A and C
... whether T-cell immunity to RV-C is similarly impaired. We measured T-cell proliferation to overlapping synthetic peptides covering the entire VP1 capsid protein of an RV-A and RV-C genotype ...
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Virus-Like Particles as Carriers for T-Cell Epitopes: Limited Inhibition of T-Cell Priming by Carrier-Specific Antibodies
... Cytotoxic T cells (CTL) are key lymphocytes for the clear- ance of many viral and bacterial infections and for the eradi- cation of ...efficient T-cell responses in the ab- sence of viral ...
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Specific T Cell Epitopes for Immunoassay Based Diagnosis of Mycobacterium tuberculosis Infection
... study, cell-mediated immune responses were monitored by using in vitro IFN-␥ assays with PBMCs isolated from whole blood and frozen until ...for cell-mediated immunity-based tuberculosis diagnosis measuring ...
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Identification of immunodominant T cell epitopes of the hepatitis B virus nucleocapsid antigen
... polyclonal T cell lines produced by PBMC stimulation with native HBcAg were specifically reactive with the relevant peptides and that (b) polyclonal T cell lines produced with synthetic ...
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HLA DQ2 and DQ8 signatures of gluten T cell epitopes in celiac disease
... of epitopes. In AJ133612 a-gliadin, the DQ2- and DQ8-restricted T cell responses were localized to 2 different regions of the protein (regions 1 and ...DQ8-restricted T cell lines were ...
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Analysis of the human T-cell response to picornaviruses: identification of T-cell epitopes close to B-cell epitopes in poliovirus.
... Twenty-nine individuals responded to poliovirus type 3, coxsackievirus B3, and encephalomyocarditis virus by proliferation of T cells, and from such cultures, 130 virus-specific T-cell l[r] ...
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Identification of T-cell epitopes on E2 protein of rubella virus, as recognized by human T-cell lines and clones.
... E2-4 peptide induced strong cytotoxic reactions of T-cell clone A9 to the MANN and EBV-BL AT cell targets but no responses to human cell lines MAJA, MST, WT-20, PRIESS, or Lg-38 with dif[r] ...
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