T cell populations
Naive T cell survival and homeostasis analysis of monoclonal and polyclonal T cell populations
... naive T cell clones that compose the peripheral pool is essential to understand the functioning o f the immune ...monoclonal T cell populations, obtained from TCR transgenic mice, as ...
156
Peptide–MHC class I tetramers can fail to detect relevant functional T cell clonotypes and underestimate antigen-reactive T cell populations
... that T cells with low-affinity TCRs function relatively poorly (10, 16, 17), and the consensus view has become that T cells with higher-affinity TCRs stain better with pMHC multimers and exhibit greater ...
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<p>Peripheral blood CD4+ T cell populations by CD25 and Foxp3 expression as a potential biomarker: reflecting inflammatory activity in chronic obstructive pulmonary disease</p>
... CD4+ T cell populations by CD25 and Foxp3 expression during the fi rst 24 h of hospitalization, which were investigated again in the stable ...+CD25+Foxp3+ T cells and CD4+CD25+Foxp3 − T ...
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Mucosal BCG Vaccination Induces Protective Lung Resident Memory T Cell Populations against Tuberculosis
... memory T cells has been shown to be essential for protective TB ...memory T cell populations that confer protection against pulmonary ...these populations, providing a framework for ...
11
Polyfunctional and IFN-γ monofunctional human CD4+ T cell populations are molecularly distinct
... polyfunctional T cells (Figure 5, B and C) might reflect prior exposure to each pathogen (all malaria volunteers were malaria naive, whereas the Influenza vaccine volunteers had been vaccinated in previous years ...
13
Regulation of human naive and memory T cell populations by apoptosis and replicative senescence
... CD8^ T Lymphocytes During EBV Infection 119 In addition, the EBV-lytic epitope specific CD45RA^ T ceils from chronic patients were able to re-express CD45RO upon re activation with specific ...This ...
194
High-throughput T cell receptor sequencing identifies clonally expanded CD8+ T cell populations in alopecia areata
... dominant T cell clones, several of these CDR3β sequences were nearly homologous to those of other dominant T cell clones (Supplemental Figure ...distinct T cell clones express- ...
15
Schistosoma mansoni Soluble Egg Antigens Enhance T Cell Responses to a Newly Identified HIV-1 Gag H-2b Epitope
... ⫹ T cell populations, and enriched CD4 ⫹ T cell populations with these ...the cell populations ...⫹ T cell responses being higher than the level of ...
7
Molecular characterization of T cell receptor beta variable in the peripheral blood T cell repertoire in subjects with active tuberculosis or latent tuberculosis infection
... different T cell clones are involved in the immune response to ...immune T-cells, resulting in the prolifera- tion of corresponding T cell clones; (2) there are various and scattered ...
10
CRISPR/Cas9-mediated knockout of CD47 causes hemolytic anemia with splenomegaly in C57BL/6 mice
... mice had a defective immune system due to reduction of mature T cell populations in the spleen. These findings confirm the role of CD47 in blood cells, indicating that our CD47 −/− mice may serve as ...
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Expansion of Fc receptor bearing T lymphocytes in patients with immunoglobulin G and immunoglobulin A myeloma
... into T and non-T cell populations by rosette- formation with sheep erythrocytes, and were then assayed for the presence of surface membrane Fc ...in T cells with IgG receptors (T ...
5
CD32+ and PD-1+ Lymph Node CD4 T Cells Support Persistent HIV-1 Transcription in Treated Aviremic Individuals
... of cell surface metal- conjugated antibodies (Table ...M Cell-ID intercalator; Fluidigm/DVS Science) in 2% PFA at 4°C ...CD4 T cell populations, FCS files were imported into Cytobank ...
14
Theileria annulata-transformed cell lines are efficient antigen-presenting cells for in vitro analysis of CD8 T cell responses to bovine herpesvirus-1
... growing cell lines infected with the protozoan parasite Theileria annulata can readily be established by in vitro infection of leukocytes with the sporozoite stage of the ...transformed cell lines could be ...
12
Gata3 restrains B cell proliferation and cooperates with p18 INK4c to repress B cell lymphomagenesis
... lymphoid cell differentiation and its function in T cell commitment and development has been extensively ...promotes T cell specification by repressing B cell potential in pro ...
14
Clinically resolved psoriatic lesions contain psoriasis specific IL 17–producing αβ T cell clones
... residual T cell populations in clinically resolved psoriatic lesions expressed mRNA for IL-17A (4); our studies dem- onstrate that IL-17A protein is also actively expressed by residual T ...
12
CD4+ T Cells Are Required for the Priming of CD8+ T Cells following Infection with Herpes Simplex Virus Type 1
... -T- cell populations generated during a primary response to acute infection with HSV-1 in mice lacking CD4 ⫹ T ...⫹ T cells produced in the absence of CD4 ⫹ T cells were found to ...
13
RGS10 deficiency ameliorates the severity of disease in experimental autoimmune encephalomyelitis
... immune cell distribution within the CNS and peripheral lymphoid tissues ...CD8+ T cells, B cells, and monocytes within the spleens, blood, and brain ...CD4+ T cells from RGS10-null mice have defects ...
12
A flexible MHC class I multimer loading system for large-scale detection of antigen-specific T cells
... antigen–specific T cells will have a strong impact on the immune monitoring of responses to infection and cancer immunotherapies, as well as vaccines (Bentzen et ...non–small cell lung cancer and renal ...
12
An HIV-1 gp120 Envelope Human Monoclonal Antibody That Recognizes a C1 Conformational Epitope Mediates Potent Antibody-Dependent Cellular Cytotoxicity (ADCC) Activity and Defines a Common ADCC Epitope in Human HIV-1 Serum
... Virus, IMCs, and chronically infected cells. The following replication-compe- tent infectious molecular clones (IMCs) of clade B HIV-1 strains were used: X4-tropic pNL4-3 (GenBank accession numbers M19921 AF324493.2) ...
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Lymphocryptovirus-dependent occurrence of lymphoma in SIV-infected rhesus macaques with particular consideration to two uncommon cases of non-Hodgkin’s lymphoma
... In addition, we focused on two cases of lymphoma in chronic SIV infection because they were special with respect to either the localization or the phenotype. Both animals presenting with tumorous masses had the ...
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