T-cell recognition
Human γδ T cell Recognition of lipid A is predominately presented by CD1b or CD1c on dendritic cells
... γδ T cells, espe- cially Vδ2 T cells in peripheral blood might play an impor- tant role in the control of infection induced by Gram- ...γδ T cells with LA results in exten- sive proliferation and ...
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Epstein-Barr virus-specific cytotoxic T-cell recognition of transfectants expressing the virus-coded latent membrane protein LMP.
... To distinguish between the viral protein and an induced human B-cell activation antigen as the target for T-cell recognition, LMP was then expressed in a murine mastocytoma cell line, P8[r] ...
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Constraints in antigen presentation severely restrict T cell recognition of the allogeneic fetus
... OT-I T cell recognition of fetal/placental ...1 cell division is noted; such cells were only rarely observed in B6-mated females at any stage of ...
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H-2 antigenic requirements for T cell recognition
... H-2 Antigenic Requirements for Cytotoxic T Cell Recognition [ l The observation that the H-2 gene complex imposes constraints on I Tc cell recognition of foreign cell surface antigens vi[r] ...
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Sequence Diversity in the pe pgrs Genes of Mycobacterium tuberculosis Is Independent of Human T Cell Recognition
... DNA sequence diversity and selection in PE_PGRS proteins. To characterize the sequence diversity of PE_PGRS proteins and the impact of human T cell recognition, we selected 27 PE_PGRS family members ...
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Alveolar epithelial cell chemokine expression triggered by antigen specific cytolytic CD8+ T cell recognition
... cell recognition may reflect either a population effect or an effect of epithelial cells as individual responders to TCR engagement (or ...specific T cell recognition that are not ...
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Simian T Lymphotropic Virus 1 Infection of Papio anubis: tax Sequence Heterogeneity and T Cell Recognition
... simian T lymphotropic virus (STLV) are a potentially useful model system for the study of vaccination against human T lym- photropic virus ...the T cell responses that rec- ognize the ...
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T-cell recognition in experimental autoimmune thyroiditis
... different T-cell subsets in the presence or absence of anti IL-2 receptor, Thl clones have been shown to produce autocrine growth factor IL-2 and IFN-y whilst the Th2 subset produces autocrine growth factor ...
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CD8+ T Cell Recognition of Cryptic Epitopes Is a Ubiquitous Feature of AIDS Virus Infection
... ⫹ T cell responses against the proteins encoded by ...B-lymphoblastoid cell lines (BLCL) pulsed with 15-mer peptides. Cell lines were tested for reactivity to 9-, 10-, and 11-mer peptides by ...
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HLA identical leukemia cells and T cell growth factor activate cytotoxic T cell recognition of minor locus histocompatibility antigens in vitro
... and cell-mediated lysis (CML) responses between the patient's remission (pretransplant) and donor's lymphocytes were ...in T cell growth factor (TCGF) generated lymphocytes that induced effective ...
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TAP independent self peptides enhance T cell recognition of immune escaped tumors
... tg T cells in WT hosts. T cell transfer in combination with pep- tide vaccination resulted in a significant delay of tumor outgrowth and survival of a quarter of the animals (Figure 6, B and C, and ...
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Targeting CLEC9A delivers antigen to human CD141+ DC for CD4+ and CD8+T cell recognition
... untargeted soluble pp65 Ag (Figure 3B). The efficacy of anti–CLEC9A-pp65 compared with the isotype con- trol and DEC-205-pp65 was evident when multiple donors were examined. CLEC9A targeting was signifi- cantly more ...
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Analysis of the primary T-cell response to Sendai virus infection in C57BL/6 mice: CD4+ T-cell recognition is directed predominantly to the hemagglutinin-neuraminidase glycoprotein.
... The specific viral components recognized by these MHC class IT-restricted hybridomas have been identified by using both recombinant vaccinia viruses Vac recombinants expressing individua[r] ...
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T cell recognition of endogenous and exogenous peptides presented by MHC molecules
... o t be overcom e com pletely b ecau se m o st o f th e m H antigens are poorly ...ulate T cell im m une responses b u t not antibody ...fic T cell lines and d o n e ...o t ...
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Molecular analysis of T cell receptors: Mapping T cell recognition and repertoire in two human immune responses
... lived T cell clones during a chronic hum an im m une response. T cell clones expressing the same TCR sequences have been isolated from both PBL and synovial fluid (SF) from a patient w ith ...
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Molecular Requirements for T Cell Recognition of N-Myristoylated Peptides Derived from the Simian Immunodeficiency Virus Nef Protein
... cytotoxic T cell attack, the short stretch of the N-terminal amino acid resi- dues of the Nef protein that contains N-myristoylation signal is hard to mutate without affecting the function of the ...
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Characterization and recognition of minor histocompatibility antigens
... FB recognition patterns as observed in figure 4, we quantified MiHA gene expression levels of 6 EBV-LCL and 4 FB by micro- array ...FB recognition (Figure 5A, right ...to T-cell ...
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Structural and functional consequences of alveolar cell recognition by CD8(+) T lymphocytes in experimental lung disease
... 1 T cell recognition of a target antigen in the lung, in the absence of any exogenous ...1 T cell tolerance to all MHC class I–restricted epitopes of HA ...gen recognition by ...
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An unusual case report of indolent T-cell lymphoproliferative disorder with aberrant CD20 expression involving the gastrointestinal tract and bone marrow
... mantle cell lymphoma (MCL) could also be confused with indolent T-cell ...indolent T-cell ...in T-cell LPD, the lack of other B-cell makers, the expression of ...
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CD56+-T-Cell Responses to Bacterial Superantigens and Immune Recognition of Attenuated Vaccines
... killer T (NKT) cells, coexpressing natural killer (NK) and T-cell receptors (TCR), are associated with immunity to viruses, tumors, and ...the cell surface glycoprotein CD1d. However, a larger ...
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