T congolense
The origins of the trypanosome genome strains Trypanosoma brucei brucei TREU 927, T b gambiense DAL 972, T vivax Y486 and T congolense IL3000
... T. congolense generally grows well in laboratory rodents and bloodstream forms of IL3000 have been grown in mice as well as bloodstream form culture ...[60,63]. T. congolense is transmissible ...
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Evaluating the impact of targeting livestock for the prevention of human and animal trypanosomiasis, at village level, in districts newly affected with T. b. rhodesiense in Uganda
... previously described [35–37]. Discs were washed four times, twice with FTA purification reagent and twice with TE buffer, before being air dried and then heated at 90 °C for 30 min suspended in 5% (w/v) Chelex solution. ...
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Trypanosoma congolense Procyclins: Unmasking Cryptic Major Surface Glycoproteins in Procyclic Forms
... respect, T. congolense procyclins resemble ...the T. congolense Kilifi stock used in this study did not establish an infection in ...that T. congolense blood- stream forms that ...
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Molecular and Biochemical Characterization of a Cathepsin B-Like Protease Family Unique to Trypanosoma congolense
... Attempts to control trypanosomiasis are based mainly on the use of trypanocidal drugs and on vector control. However, because no new drugs have been developed in the last 50 years, drug resistance is increasing. Efforts ...
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A comprehensive genetic analysis of candidate genes regulating response to Trypanosoma congolense infection in mice
... A functional toll like receptor 4 (Tlr4) gene is necessary for maximal control of Trypanosoma cruzi in mice [33] and there is evidence that the GPI anchor of T. brucei VSG has endotoxin like properties that could ...
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Variant antigen repertoires in Trypanosoma congolense populations and experimental infections can be profiled from deep sequence data with a set of universal protein motifs
... (SNP), estimated with RAxML (Stamatakis 2014) with a GTR+ Γ model and 100 bootstrap replicates (branches with bootstrap >70 are shown in bold). Labels ‘i’ to ‘v’ denote examples referred to in the text. Label ‘i’ ...
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Detection of multiple drug resistant Trypanosoma congolense populations in village cattle of south east Mali
... The results of this study confirmed the presence of ap- parent multiple drug-resistant T. congolense and isome- tamidium resistant T. vivax populations in village cattle of south-east Mali. This ...
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Effects of experimental Trypanosoma congolense infection on sperm morphology in Yankasa rams
... group remained uninfected. The entire infected group developed trypanosomosis post infection (pi) characterized by sperm morphological abnormalities in the semen. There were significant (P<0.001) increases in the mean ...
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Trypanocidal activity of ethanolic extracts of Commiphora swynnertonii Burtt on Trypanosoma congolense
... Results for in vitro trypanosomes drug incubation, followed by an assessment of infectivity to mice are summarized in Table 3. All the mice in group 1 were found to be infected at day 4 post inoculation. There was ...
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Genetic and expression analysis of cattle identifies candidate genes in pathways responding to Trypanosoma congolense infection
... This combination of genetic, in vitro analysis and expression data has provided unique insights into the differences between sus- ceptible Boran and tolerant N’Dama cattle in their response to infection with T. ...
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Expression profiling of Trypanosoma congolense genes during development in the tsetse fly vector Glossina morsitans morsitans
... cultured T. congolense stages where GARP is preferentially expressed by EMF stage parasites [26, 83] in tsetse’s PB ...in T. congolense is unknown, but their ...of T. congolense ...
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In Vivo anti trypanosomal activity of dichloromethane and methanol crude leaf extracts of Dovyalis abyssinica (Salicaceae) against Trypanosoma congolense
... Further deduction of the anti-trypanosomal activity of the plant can be made from the weight gain observed in mice treated with the higher (250, 200 mg/kg) doses of extracts. In the present study, infected mice ...
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Haemoassessment of Dogs Experimentally Infected with Single and Conjunct Trypanosoma congolense and Ancylostoma caninum and Treatment with Diminazene Aceturate and Mebendazole
... with T. congolense, and GROUP III was mixed infections of ...T. congolense and ...later, T. congolense infection was done on GPII and ...
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Evaluation of in vivo antitrypanosomal activity of crude extracts of Artemisia abyssinica against aTrypanosoma congolense isolate
... of T. congolense that were originally isolated from a pure natural infection of cattle in Arba Minch, Ethiopia were obtained from the School of Veterinary Medicine, Addis Ababa ...
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In vivo effect of Commiphora swynnertonii ethanolic extracts on Trypanosoma congolense and selected immunological components in mice
... Handling of animals was done in accordance to OECD guidelines [23]. The mice were kept in plastic cages 275 × 160 × 130 mm, five mice per group with wood shav- ings as bedding and identified with picric acid markings. ...
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Symptoms and Response to Treatment with Diminazene Aceturate and Mebendazole in Dogs Infected with Single Trypanosoma congolense, Ancylostoma caninum and Combination of Trypanosoma congolense and Ancylostoma caninum
... The symptoms manifested in the infected dogs are shown in Table 3. The symptoms of T. congolense and A. caninum were only observed by day 42 post infections. Symptoms shown include: Dark coloured foal ...
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Evidence for viable and stable triploid Trypanosoma congolense parasites
... triploid T. congolense parasites can complete a full life- cycle, and that triploid populations in the field are viable and sustained in host ...of T. congolense populations during each stage ...
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Population genetics of forest type of Trypanosoma congolense circulating in Glossina palpalis palpalis of Fontem in the South West region of Cameroon
... for T. congolense forest [21]; and TCS1 (5 ′ -TCGAGCGAGAACGGGCAC TTTGCGA-3 ′ ) and TCS2 (5 ′ -ACAATTAGGGACAAAC AAATCCCGC-3 ′ ) for ...T. congolense savannah ...
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Equine trypanosomosis: enigmas and diagnostic challenges
... Oral transmission of T. evansi via contaminated meat or carcasses is well documented but normally does not occur in equines [10, 11]. Trypanosoma vivax can be transmitted both cyclically by tsetse flies and ...
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The life cycle of Trypanosoma (Nannomonas) congolense in the tsetse fly
... of T. congolense can be reliably reproduced in vitro and cultures yield large numbers of trypano- somes of different life cycle stages ...of T. congolense epimasti- gotes to attach to a ...
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