T-helper cells type 1
Transient Mobilization of Human Immunodeficiency Virus (HIV)-Specific CD4 T-Helper Cells Fails To Control Virus Rebounds during Intermittent Antiretroviral Therapy in Chronic HIV Type 1 Infection
... CD8 T cells when they were unde- tectable by using a panel of peptides representative of the four major HIV proteins (Gag, Pol, Env, and ...CD8 T cells in the two cases where they were ...
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In vitro Effects of Propranolol on T Helper Type 1 Cytokine Profile in Human
... In our study, propranolol reduced IFN-γ and IL-2 (Th1 cytokines) production. As Th1 cells have essential anti-tumor properties, 29 we might conclude that propranolol decreases anti-cancer immune responses. But ...
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Purified protein derivative of Mycobacterium tuberculosis and excretory secretory antigen(s) of Toxocara canis expand in vitro human T cells with stable and opposite (type 1 T helper or type 2 T helper) profile of cytokine production
... that T cells with stable Th1 or Th2 functional pattern exist not only in mice but also in humans and suggest that in the course of natural immunization certain infectious agents preferentially expand ...
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T Helper 22 Pathway Evaluation in Type 1 Diabetes and Its Complications
... Th22 cells (by flow cytometry), serum level of Th22 related cytokines including Interleukin-22 (IL-22), Interleukin-10 (IL-10), Transforming growth factor-β (TGF-β), Tumor necrosis factor-α (TNF-α) (by ELISA) and ...
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Productive and lytic infection of human CD4+ type 1 helper T cells with macrophage-tropic human immunodeficiency virus type 1.
... Th0 cells produce both Th1- and Th2-type ...HIV- 1-infected individuals does not occur at the clonal CD4 1 T-cell level; instead, they have suggested that a shift from Th1 to Th0 occurs ...
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Early molecular replication of human immunodeficiency virus type 1 in cultured blood derived T helper dendritic cells
... primary T cell and monocyte ...the T helper dendritic cells, as compared with that in other cell types, or to an increased efficiency and rate of viral DNA synthesis in the T ...
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Plasma levels of monokine induced by interferon-gamma/chemokine (C-X-X motif) ligand 9, thymus and activation-regulated chemokine/chemokine (C-C motif) ligand 17 in children with Kawasaki disease
... blood cells (WBC), C-reactive protein (CRP) and erythrocyte sedimentation rate ...(ESR). T cells activation has been reported to be participated in the immunological pathogenesis [3, 4], and some ...
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Increased Circulating T Follicular Helper Cells in Iranian Children with Type I Diabetes
... A total of 20 patients with T1D (11 girls and 9 boys; age: 7.5±0.9 years; range: 1-15 years) were enrolled in this study. The duration of the disease was 186.76±95.8 days (disease duration≤300 days from the ...
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Interleukin-17 and type 17 helper T cells in cancer management and research
... These cells can mediate antitumoral effects by their ability to recruit immune effector cells (CTL, NK, DC) into the tumor bed and they can promote tumor growth by means of angiogenesis (pro- duction of ...
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Adenoviruses Activate Human Dendritic Cells without Polarization toward a T-Helper Type 1-Inducing Subset
... rAd infection and CD40 ligation act in synergy to trigger DC maturation. The intermediate activation state of rAd-infected DC suggested either that the activation signals provided by rAd were insufficient to trigger full ...
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Hydrophilic Astragalin Galactoside Induces T Helper Type 1-Mediated Immune Responses via Dendritic Cells
... Total RNA that was obtained from the cells was reverse-transcribed into cDNA, and then PCR amplification of the cDNA was performed using a thermal cycler (Bioneer, Daejeon, Korea). The sequences of the PCR primers ...
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Early Induction and Maintenance of Env-Specific T-Helper Cells following Human Immunodeficiency Virus Type 1 Infection
... no. 1 by multiplex RT-PCR and agarose gel ...clones 1, 2, 3, 4, and 5 by using the TCRBC ...clones 1 and 2 sharing identical ...clones 1 and 2 versus clones 3, 4, and 5 are indicated in ...no. ...
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Treatment with depleting CD4 monoclonal antibody results in a preferential loss of circulating naive T cells but does not affect IFN gamma secreting TH1 cells in humans
... CD45RA(neg)/R0(pos) T cells. Notably, within the CD45RA(pos) subset, T cells with phenotypic evidence of prior activation, ...Fas(neg) cells. Remarkably, while a decrease in the number ...
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Distinct gene expression profiles of human type 1 and type 2 T helper cells
... Th1 cells as compared to Th2 ...human T cells has been reported ...the type 2 cells has somewhat fewer inflammatory mediators than Th1 ...Th2 cells than in Th1 ...in type ...
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Abnormal CD4 + T helper (Th) 1 cells and activated memory B cells are associated with type III asymptomatic mixed cryoglobulinemia in HCV infection
... by T cells and B cells with MC in chronic hepatitis C (CHC) patients is poorly ...with T helper (Th) 1 immune responses, were found to be involved in HCV-related type II ...
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Follicular helper T cell signature in type 1 diabetes
... of T cell differentiation as a Th1/Th2 dichotomy, with Th1 cells responsible for tissue-specific autoimmunity, has led numerous researchers to hunt for a Th1 signature in T1D, with widely variable ...memory ...
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Multiple myeloma presenting as cutaneous leukocytoclastic vasculitis and eosinophilia disclosing a T helper type 1/T helper type 2 imbalance: a case report
... The use of immunomodulatory drugs, such as thal- idomide and lenalidomide, and the proteasome inhibi- tor bortezomib have been associated with improved survival in the relapsed and front-line settings, as re- cently ...
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Original Article Transformations of peripheral T cell subset distributions in oral cancer patients and the effect of P53 gene therapy in a short time
... immune cells and thus plays a regulatory role in the proliferation and function of these ...tumor cells actives T cells as a tumor specific antigen ...tumor cells that transfected by ...
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Cytokine profile and induction of T helper type 17 and regulatory T cells by human peripheral mononuclear cells after microbial exposure
... able to withstand the harsh physiological conditions (Table 2) [4, 45]. Pro-inflammatory cytokine production was measured following co-cultured of GIT simulated bacteria with the different cells as above. In ...
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HIV and T follicular helper cells: a dangerous relationship
... TFH cells extracted from HIV-infected individuals expressed more BCL-6 — the transcription factor required for TFH formation and maintenance (19) — than those from treat- ed or uninfected subjects (4) (Figure ...
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