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Tandem Mass Spectrometry

Denoising Tandem Mass Spectrometry Data

Denoising Tandem Mass Spectrometry Data

... Tandem mass spectrometry, commonly known as tandem MS/MS is a mass spec- trometry comprised of two stages of the mass ...two mass analyzers in tandem MS/MS. The ...

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Analysis of posttranslational modifications of proteins by tandem mass spectrometry

Analysis of posttranslational modifications of proteins by tandem mass spectrometry

... by mass spectrometry (MS), either as a mass increment or a mass deficit relative to the nascent unmodified ...protein. Tandem mass spectrometry (MS/MS) provides a series ...

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Algorithms for Glycan Structure Identification with Tandem Mass Spectrometry

Algorithms for Glycan Structure Identification with Tandem Mass Spectrometry

... with tandem mass spectrometry are database search and de novo ...from tandem mass spectra, without the assistance of any structural knowledge of ...of mass spectrometry ...

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Economic Evaluation of Tandem Mass Spectrometry Screening in California

Economic Evaluation of Tandem Mass Spectrometry Screening in California

... T HE California legislature authorized and funded a pilot tandem mass spectrometry (MS/MS) screening program, which was conducted from January 7, 2002, through June 13, 2003. During that period, 755 ...

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A Tandem Mass Spectrometry Sequence Database Search Method for Identification of O-Fucosylated Proteins by Mass Spectrometry.

A Tandem Mass Spectrometry Sequence Database Search Method for Identification of O-Fucosylated Proteins by Mass Spectrometry.

... standard tandem mass spectrometry (MS/MS) sequence database search engines because O-linked glycans are highly labile in the gas phase and are effectively absent from the CID peptide fragment ...

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Newborn screening using tandem mass spectrometry: A systematic review

Newborn screening using tandem mass spectrometry: A systematic review

... 29 Liebl B, Nennstiel-Ratzel U, von Kries R, Fingerhut R, Olgemoller B, Zapf A et al. Very high compliance in an expanded MS-MS-based newborn screening program despite written parental consent. Prev Med 2002;34:127-31. ...

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Multifactorial modeling of ion abundance in tandem mass spectrometry experiments

Multifactorial modeling of ion abundance in tandem mass spectrometry experiments

... of mass spectrometry ...the mass of amino acids residues and can fragment peptides in seconds rather than in ...with tandem mass spectrometry (MS/MS) which uses Collision Induced ...

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Determination of Creatinine in Human Urine with Flow Injection Tandem Mass Spectrometry

Determination of Creatinine in Human Urine with Flow Injection Tandem Mass Spectrometry

... dilution tandem mass spectrometry with quali- fier ion monitoring ensured unbiased quantitation and qualification of creatinine in every single ...

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Proteomic analysis of endodontic infections by liquid
chromatography–tandem mass spectrometry

Proteomic analysis of endodontic infections by liquid chromatography–tandem mass spectrometry

... 2 School of Medicine, University of Maryland Baltimore, Baltimore, MD, USA Abstract Introduction—Endodontic infections are very prevalent and have a polymicrobial etiology characterized by complex interrelationships ...

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Characterisation of phosphorylated nucleotides by collisional and electron-based tandem mass spectrometry

Characterisation of phosphorylated nucleotides by collisional and electron-based tandem mass spectrometry

... Sample solutions were infused directly into an electrospray ionisation (ESI) source at 5 μL min 1 , from which positive ions were chosen for analysis. A heated capillary was set to 350°C and a sheath gas (nitrogen) ...

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Improvements in electrospray ionization source design and advances in tandem mass spectrometry

Improvements in electrospray ionization source design and advances in tandem mass spectrometry

... Chapter 8 Conclusions and Future Directions 8.1 Summary The work described in the previous chapters involved the development of methods aimed at improving the information content from tandem mass ...

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Characterisation of phosphorylated nucleotides by collisional and electron-based tandem mass spectrometry.

Characterisation of phosphorylated nucleotides by collisional and electron-based tandem mass spectrometry.

... All mass spectrometric measurements were performed on a hybrid linear ion trap–Fourier transform-ion cyclotron mass spectrometer equipped with a ...For tandem mass spectrometry the ...

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Characterisation of phosphorylated nucleotides by collisional and electron-based tandem mass spectrometry

Characterisation of phosphorylated nucleotides by collisional and electron-based tandem mass spectrometry

... vibrational tandem mass spectrometric behaviour, with loss of phosphate groups predominantly observed owing to the labile nature of the ...from tandem mass spectrometry, including the ...

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Improved methods of tandem mass spectrometry for proteomics applications in a quadrupole ion trap mass spectrometer

Improved methods of tandem mass spectrometry for proteomics applications in a quadrupole ion trap mass spectrometer

... separation Mass spectrometry is generally thought to be much less time consuming than HPLC when only a single dimension of mass analysis is ...However, mass spectrometry will also ...

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Implementation and evaluation of amyloidosis subtyping by laser-capture microdissection and tandem mass spectrometry

Implementation and evaluation of amyloidosis subtyping by laser-capture microdissection and tandem mass spectrometry

... Peter Mollee 1* , Samuel Boros 2 , Dorothy Loo 3 , Jayde E. Ruelcke 3 , Vanessa A. Lakis 3 , Kim‑Anh Lê Cao 3 , Patricia Renaut 2 and Michelle M. Hill 3* Abstract Background: Correct identification of the ...

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Detection of stanozolol in environmental waters using liquid chromatography tandem mass spectrometry

Detection of stanozolol in environmental waters using liquid chromatography tandem mass spectrometry

... Nawed IK Deshmukh 1* , James Barker 1 , Andrea Petroczi 2 and Declan P Naughton 2 Abstract Background: Owing to frequent administration of a wide range of pharmaceutical products, various environmental waters have been ...

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The Application of Electrospray Tandem Mass Spectrometry for de novo Sequencing of Reduced Insulins

The Application of Electrospray Tandem Mass Spectrometry for de novo Sequencing of Reduced Insulins

... Keywords Insulin, Tandem Mass Spectrometry, Electrospray, de novo Sequencing 1. Introduction Diabetes is currently an incurable and potentially life-threatening disorder that occurs in patients whose ...

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Determination of pyrethroid pesticide residues in rice by gas chromatography tandem mass spectrometry

Determination of pyrethroid pesticide residues in rice by gas chromatography tandem mass spectrometry

... –tandem mass spectrometry (GC-MS/MS) was ...through tandem mass spectrometry (GC-MS/MS) with electron ionization source in Multiple reaction monitor mode (MRM) for quantification ...

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Hybrid Mass Spectrometers for Tandem Mass Spectrometry

Hybrid Mass Spectrometers for Tandem Mass Spectrometry

... Hybrid MS/MS instruments use various combina- tions of these analyzers to obtain desirable performance characteristics for the phenomena being investigated. Typically, resolving power and measurement accuracy in each ...

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Tandem mass spectrometry of polymeric materials

Tandem mass spectrometry of polymeric materials

... Surface induced dissociation (SID) spectra of peptides were obtained by means of a four sector mass spectrometer with a modified collision cell in the third field free regi[r] ...

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