Tandem mass spectrometry based identification
Algorithms for Glycan Structure Identification with Tandem Mass Spectrometry
... calculation based on the given glycan structure database in order to find the connecting frequencies (or probabilities) between each pair of monosaccharide ...
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LipidBlast in silico tandem mass spectrometry database for lipid identification.
... predict mass spectral peak intensities using peak intensities from experimentally measured spectra 18 ...of mass spectral peak abundances given a compound structure only 1 ...different mass ...
18
Denoising Tandem Mass Spectrometry Data
... of mass spectrometry (MS) in recent years, has become a significant approach in biological research for peptide identification ...of mass spectrometers, but one important component employed by ...
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Identification of Glycopeptides with Multiple Hydroxylysine O-Glycosylation Sites by Tandem Mass Spectrometry
... Collagen glycopeptide characterization problem Given an MS/MS spectrum, an un- modified peptide, and a number m, find a glycoform of the peptide with m monosaccharides that maximizes the peak counting score between the ...
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Context-sensitive Markov Models for Peptide Scoring and Identification from Tandem Mass Spectrometry
... complex interactions are either heuristically determined or learned automatically from large datasets of validated high-confidence PSMs and utilized in scoring systems. Nevertheless, the performance is still far from ...
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Bioinformatics solutions for confident identification and targeted quantification of proteins using tandem mass spectrometry
... excluded because they provide proteomics software as part of larger product bundles, and it would be virtually impossible to consider the two revenue streams separately. This may cause a bias, since the MS vendors (such ...
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Tandem mass spectrometry of biomolecules : applications and new methods
... ion mass-to-charge value and the CID data is ...the identification are shown in Figure ...molar mass and the CID fragmentation ...ions based on the Mascot derived ...made based on ...
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Identification of pathogens from native urine samples by MALDI-TOF/TOF tandem mass spectrometry
... MALDI‑TOF/TOF mass spectrometry results Protein identifications and data analysis While BioTyper and Vitek use reference databases to identify and classify the microorganisms according to their mass ...
9
Applicatins of liquid chromatography-tandem mass spectrometry to wine analysis : targeted analysis and compound identification
... Chapter 6: SPE-LC-MS/MS method for the analysis of ethyl carbamate 136 6.3.4.3. Distilled spirits The EC content of South African distilled spirits ranged between 1.9 and 95 µg/L (RSD = 104%) in 35 samples. From a South ...
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Filtering Methods for Mass Spectrometry-based Peptide Identification Processes
... dataset. Based on defined features, these methods assess the quality of MS/MS spectra through the use of supervised machine learning methods that require labelled training datasets to train a ...peptide ...
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Identification of the OXA 48 Carbapenemase Family by Use of Tryptic Peptides and Liquid Chromatography Tandem Mass Spectrometry
... Expert rules. Expert rules for classifying samples as positive or negative for the detection of OXA-48 family carbapenemase members were constructed using the assay development data. Skyline 3.7 was used to inspect all ...
13
Immuno tandem mass spectrometry (iMALDI) assay for clinical diagnostics
... New proteomics technologies, such as surface-enhanced laser desorption/ionization MS (SELDI), are used to identify potential cancer biomarkers (61-65). In SELDI, bait proteins, such as antibodies, are immobilized on ...
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Economic Evaluation of Tandem Mass Spectrometry Newborn Screening in Australia
... early identification of conditions through MS/MS ...was based on the idea that there is inadequate information to quantify costs and outcomes into adulthood, and these were largely omitted from this ...
9
Identification of Monosialylated N-glycoforms in the CDG Urinome by Ion Mobility Tandem Mass Spectrometry: The Potential for Clinical Applications
... subsequently, mass analyzed by the ...C, based upon their m/z and drift time ...produce mass spectra containing predominantly singly, doubly, and triply charged ion ...
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A novel scoring schema for peptide identification by searching protein sequence databases using tandem mass spectrometry data
... interpreting mass spectrum data can becategorized into two types: database searching methods and 'de novo' approaches independent of ...are based on shared ...
8
Proteomic analysis of endodontic infections by liquid chromatography–tandem mass spectrometry
... Preoperative specimen samples taken from seven patients with primary or persistent infections were used for proteomic analysis of endodontic infections. Diversity and prevalence of bacterial phylotypes in these samples ...
11
Glycoproteomics based on tandem mass spectrometry of glycopeptides
... ing mass spectrometric analysis in sodiated or deprotonated form and linkage analysis by GC–MS providing detailed struc- tural information, as reviewed by others ...
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A Tandem Mass Spectrometry Sequence Database Search Method for Identification of O-Fucosylated Proteins by Mass Spectrometry.
... vivo. Mass spectrometry (MS) is typically the method of choice for high-throughput detection of protein post-translational modifications (PTMs) because a moiety covalently bound to a peptide can be directly ...
25
Hybrid Mass Spectrometers for Tandem Mass Spectrometry
... Hybrid MS/MS instruments use various combina- tions of these analyzers to obtain desirable performance characteristics for the phenomena being investigated. Typically, resolving power and measurement accuracy in each ...
12
Tandem mass spectrometry of polymeric materials
... Surface induced dissociation (SID) spectra of peptides were obtained by means of a four sector mass spectrometer with a modified collision cell in the third field free regi[r] ...
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