Targeted metabolomics
Association between serum haptoglobin and carotid arterial functions: usefulness of a targeted metabolomics approach
... To summarize, we show that a number of blood metabo- lites, especially PCs and lyso-PCs, were associated with serum Hp levels and blood lipid metabolism by using a targeted metabolomics approach in Chinese ...
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Interlaboratory Reproducibility of a Targeted Metabolomics Platform for Analysis of Human Serum and Plasma.
... this targeted metabolomics assay in the context of a panel of different test human plasma and serum samples, and also compared the effects of different anticoagulants on ...widely-used, targeted ...
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Measurement of 1,5 anhydroglucitol in blood and saliva: from non targeted metabolomics to biochemical assay
... All statistical analyses were performed using R version 3.1.3 and R-Studio version 0.97.551. The package ‘stats’ version 3.1.3 was used to calculate linear regression. For each identified metabolite the raw area ion ...
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Metabolic engineering of a tyrosine-overproducing yeast platform using targeted metabolomics
... a targeted metabolomics approach was employed to systematically examine the impacts of multiple metabolic engineering strategies for the production of tyrosine in ...
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Non-targeted and targeted metabolomics approaches to diagnosing lung cancer and predicting patient prognosis
... be targeted or non-targeted. Targeted metabolomics refers to the quantitative measurement of a select group of metabolites ...[16]. Targeted approaches require a priori knowledge of ...
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Non targeted metabolomics in sport and exercise science
... non-targeted metabolomics to identify novel markers of stress in salivary samples include observed elevations in metabolic by-products such as 3-methylhistidine ...
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Targeted metabolomics in colorectal cancer: a strategic approach using standardized laboratory tests of the blood and urine
... complex metabolomics profiling, we hypothesized that charged and uncharged small molecule metabolites of CRC could be detected using standard anion gap (AG) and osmolar gap ...
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Development of a non-targeted metabolomics method to investigate urine in a rat model of polycystic kidney disease
... Gas chromatography chromatograms and mass spectra were viewed using AnalyzerPro v2.2.0.7 (SpectralWorks, Runcorn, UK). All unique components of the chromatogram were identified and, where possible, matched to an in-house ...
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Targeted metabolomics reveals the therapeutic impact of Eclipta prostrata on diet-induced non-alcoholic fatty liver disease in rats
... Lipidomic analysis showed a discrete variability in the levels of some metabolites, including cholest-5-en-3-ol (3β) – acetate; cholesta-4, 6-dien-3-ol, (3β); urea; 1,3 dipalmitin; gly[r] ...
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Alterations in arginine and energy metabolism, structural and signalling lipids in metastatic breast cancer in mice detected in plasma by targeted metabolomics and lipidomics
... cancer. Metabolomics, as the endpoint of the ‘omics’ cascade, is focused on the investigation of the global metabolites present in a biological specimen and is considered representative of the phenotype ...hand, ...
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Functional Metabolomics – a Useful Tool to Characterize Stress-Induced Metabolome Alterations Opening New Avenues Towards Tailoring Food Crop Quality
... Especially, targeted metabolomics approaches enables the possibility to monitor marker compounds up-regulated during plant stress, which then can be isolated, identified and biologically characterized, for ...
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Livestock metabolomics – A overview
... importance for biomarker study and the variation by the “level” in which this metabolomic information is placed after gene expression and protein production. These variants usually explain a high fraction (10–30%) of the ...
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Genome-wide association studies with metabolomics
... Nontargeted metabolomics provides information on the simultaneous presence of many metabolites or features (for example, peaks or ion ...nontargeted metabolomics is its unbiased approach to the ...
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Ultra-weak photon emission as a dynamic tool for monitoring oxidative stress metabolism
... pathogenicity in many diseases. The advent of a simple tool that can provide a physiological readout of oxidative stress would be a major step towards monitoring this dynamic process in biological systems, while also ...
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Persistent metabolic changes in HIV-infected patients during the first year of combination antiretroviral therapy
... Using targeted metabolomics and multiplex immune biomarker analysis, we characterized plasma samples obtained from 18 untreated HIV-1-infected adult patients and compared these to a non-HIV infected (n = ...
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The metabolomics of psoriatic disease
... approaches. Targeted metabolomics involves the analysis of a prespecified set of metabolites, often related to a particular pathway or network of pathways of ...untargeted metabolomics are very ...
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PubMedCentral-PMC5310942.pdf
... non-targeted metabolomics analysis on gastrocnemius muscle samples of adult and old, Sham and ALI mice at day ...the metabolomics profile, with the first principal component accounting for ...
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Next-generation biomarker discovery in Alzheimer's disease using metabolomics - from animal to human studies
... phenotype, metabolomics is an ideal approach for identification of new ...of metabolomics in the field of AD research, focusing on animal and human studies, and discusses the improvements carried out over ...
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COordination of Standards in MetabOlomicS (COSMOS): facilitating integrated metabolomics data access
... for metabolomics standards started in 2004–2005 with initiatives such as the standard metabolic reporting structure initiative or SMRS (Lindon et ...for Metabolomics consortium or Armet (Jenkins et ...of ...
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Metabolomics of Rhabdomyosarcoma Cell During Echovirus 30 Infection
... The present study shows the metabolomics of E30 infected mammalian cells. The NMR analysis revealed no ambigu- ous signals using the RD cell line. The present proton NMR spectroscopic study, monitoring cellular ...
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