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TB drugs

 ANTIHEPATOTOXIC EFFECT OF BARLERIA MONTANA LEAVES AGAINST ANTI-TB DRUGS INDUCED HEPATOTOXICITY

 ANTIHEPATOTOXIC EFFECT OF BARLERIA MONTANA LEAVES AGAINST ANTI-TB DRUGS INDUCED HEPATOTOXICITY

... anti-TB drugs induced ...anti-TB drugs once daily for 35 days and simultaneously 95% hydroalcoholic extract of Barleria Montana (250 & 500 mg/kg ...ALP, TB & total cholesterol ...

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Suboptimal Exposure to Anti-TB Drugs in a TBM/HIV+ Population is not Related to Anti-retroviral Therapy.

Suboptimal Exposure to Anti-TB Drugs in a TBM/HIV+ Population is not Related to Anti-retroviral Therapy.

... anti-TB drugs that are concomitantly administered with ART which could adversely affect the efficacy or toxicity of some these drugs in this patient ...ART drugs used in HIV and anti TB ...

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THE ADME/T PROFILES OF TB DRUGS – AN IN SILICO ANALYSIS

THE ADME/T PROFILES OF TB DRUGS – AN IN SILICO ANALYSIS

... oral drugs Isoniazid, Pyrazinamide, Aminosalicylic Acid and Ethionamide have very few deviations from the range of values calculated from 95% of known drugs and Streptomycin and Kanamycin being injectable ...

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Treating tuberculosis with high doses of anti-TB drugs: mechanisms and outcomes

Treating tuberculosis with high doses of anti-TB drugs: mechanisms and outcomes

... Tuberculosis (TB) is considered as one of the most serious threats to public health in many parts of the world. The threat is even more severe in the developing countries where there is a lack of advanced medical ...

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Pharmacokinetics of anti-TB drugs in Malawian children: reconsidering the role of ethambutol

Pharmacokinetics of anti-TB drugs in Malawian children: reconsidering the role of ethambutol

... range studied, whereas for rifampicin CL/F appeared to decrease around 4 years, ultimately halving over the age range. These changes may reflect the greater relative liver size and blood flow per kilogram in younger ...

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OVERVIEW OF NEW ANTI TB DRUGS

OVERVIEW OF NEW ANTI TB DRUGS

... 6. Ethionamide (ETA) is a thioamide antibiotic and one of the most widely used drugs as second line agent for the treatment of MDR-TB. Over the years, some studies have emerged to improve the ...

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Rapid Molecular Detection of Tuberculosis and Rifampicine Resistance in Ecuador

Rapid Molecular Detection of Tuberculosis and Rifampicine Resistance in Ecuador

... of TB as re- ferred by Reyes et ...time, TB was the leading cause of death among HIV ...for TB cases among people with HIV [4] and to optimize these treatments since anti-TB drugs ...

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Extensively drug-resistant tuberculosis: epidemiology and management

Extensively drug-resistant tuberculosis: epidemiology and management

... to drugs. The incorrect use of anti-TB drugs, either due to prescription errors, low patient compliance, or poor quality of drugs, led to the widespread emergence of Mycobacterium tuberculosis ...

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Prevalence and patterns of drug resistance among pulmonary tuberculosis patients in Hangzhou, China

Prevalence and patterns of drug resistance among pulmonary tuberculosis patients in Hangzhou, China

... anti-TB drugs were from the new cases ...initiate TB treatment ...MDR TB preva- lence among newly diagnosed in Ethiopia in East Africa was ...treated TB patients, 14.1% (95% CI, ...

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Minor contribution of mutations at iniA codon 501 and embC-embA intergenic region in ethambutol-resistant clinical Mycobacterium tuberculosis isolates in Kuwait

Minor contribution of mutations at iniA codon 501 and embC-embA intergenic region in ethambutol-resistant clinical Mycobacterium tuberculosis isolates in Kuwait

... from TB patients with limited previous exposure to first-line anti-TB drugs usually contain single point mutations in resistance conferring genes while strains from previously treated patients ...

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Predictor of multidrug resistant tuberculosis in southwestern part of Ethiopia: a case control study

Predictor of multidrug resistant tuberculosis in southwestern part of Ethiopia: a case control study

... anti-TB drugs had about five times more chance of developing MDR-TB than their ...anti-TB drugs or drug interactions can make it necessary to modify or discontinue treat- ...

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A PROSPECTIVE OBSERVATIONAL STUDY ON PRESCRIPTION PATTERN, DRUG UTILIZATION AND AUDIT FOR THE TREATMENT OF TUBERCULOSIS IN A TERTIARY CARE HOSPITAL IN ANDHRA PRADESHK.P.R.Chowdary*, G Sumalatha, K. Sri Gouri and K.J.S.Dani DOWNLOAD/VIEW

A PROSPECTIVE OBSERVATIONAL STUDY ON PRESCRIPTION PATTERN, DRUG UTILIZATION AND AUDIT FOR THE TREATMENT OF TUBERCULOSIS IN A TERTIARY CARE HOSPITAL IN ANDHRA PRADESHK.P.R.Chowdary*, G Sumalatha, K. Sri Gouri and K.J.S.Dani DOWNLOAD/VIEW

... The objective of the observational study is to evaluate the prescription pattern, drug utilization and audit of anti-TB drugs usage in a tertiary care hospital in Rajahmundry, Andhra Pradesh. Audit is a ...

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Use of anti-tuberculosis drugs among newly diagnosed pulmonary tuberculosis inpatients in China: a retrospective study

Use of anti-tuberculosis drugs among newly diagnosed pulmonary tuberculosis inpatients in China: a retrospective study

... have likely been a main factor affecting the irrational use of medicines in China [13, 20, 21]. Chinese hospitals are not fully financed by public funds; thus, they need to generate a substantial amount of revenue to ...

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Comparison between the BACTEC MGIT 960 system and the agar proportion method for susceptibility testing of multidrug resistant tuberculosis strains in a high burden setting of South Africa

Comparison between the BACTEC MGIT 960 system and the agar proportion method for susceptibility testing of multidrug resistant tuberculosis strains in a high burden setting of South Africa

... Standardised, rapid and accurate drug susceptibility testing (DST) methods for first-line and second-line anti-TB drugs is important to determine an effective treatment regimen and to decrease transmission. ...

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Mandatory TB notification in Mysore city, India: Have we heard the private practitioner’s plea?

Mandatory TB notification in Mysore city, India: Have we heard the private practitioner’s plea?

... Fourth, the practitioners had varied opinion regarding legal action in case the practitioner failed to notify. The failure to notify could be done by collecting information about the practitioner and the patient from the ...

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Clinical Response to Treatment of Central Nervous System Tuberculosis in Non Human Immunodeficiency Virus Infected Adolescents and Adults

Clinical Response to Treatment of Central Nervous System Tuberculosis in Non Human Immunodeficiency Virus Infected Adolescents and Adults

... CNS TB. The diagnosis of CNS TB was classified as confirmed or probable ...probable TB when chest radiography images showed active lesions, there was response to anti-TB therapy, or when CNS ...

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Assessment of the Prevalence of Hepatotoxicity Among Hiv/Tb Coinfected Patients in Adama Referral Hospital, Adama, Ethiopia

Assessment of the Prevalence of Hepatotoxicity Among Hiv/Tb Coinfected Patients in Adama Referral Hospital, Adama, Ethiopia

... Worldwide, it is estimated that 14.8% of all new tuberculosis (TB) cases in adults are attributable to human immunodeficiency virus (HIV) infection. This proportion is much greater in Africa, where 79% of all ...

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The Effectiveness of Surgical Methods of Treatment of Pulmonary Tuberculosis for Patients with Multidrug Resistant at Adequate Chemotherapy (Retrospective, Case Control, Comparative Research)

The Effectiveness of Surgical Methods of Treatment of Pulmonary Tuberculosis for Patients with Multidrug Resistant at Adequate Chemotherapy (Retrospective, Case Control, Comparative Research)

... the drugs of the reserve line has been compared with two control groups: Group I—Surgical intervention was implemented with drugs of the first line, Group II—Chemo- therapy was conducted with anti-TB ...

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Novel targeting of PEGylated liposomes for codelivery of TGF-β1 siRNA and four antitubercular drugs to human macrophages for the treatment of mycobacterial infection: a quantitative proteomic study

Novel targeting of PEGylated liposomes for codelivery of TGF-β1 siRNA and four antitubercular drugs to human macrophages for the treatment of mycobacterial infection: a quantitative proteomic study

... anti-TB drugs with linkage to small interfering RNA (siRNA) against transforming growth factor-β1 ...anti-TB drugs and TGF-β1 siRNA were endocytosed efficiently by human macrophages as ...

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Intra individual effects of food upon the pharmacokinetics of rifampicin and isoniazid

Intra individual effects of food upon the pharmacokinetics of rifampicin and isoniazid

... taking TB drugs with meals is associated with a poor response to treatment, an impact that could be hypothesized might result from lower drug ...(taking TB drugs in an unfasted state) was ...

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