tegument proteins
Analysis of the Interaction between the Essential Herpes Simplex Virus 1 Tegument Proteins VP16 and VP1/2
... ment proteins pUL41, VP11/12, VP13/14, and VP22 (6, 32, 36, 40) and the cytoplasmic domains of glycoproteins B, D, and H (12, 16, 41), offering VP16 a plethora of possible interactions for incorpo- ration into ...
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Assemblons: nuclear structures defined by aggregation of immature capsids and some tegument proteins of herpes simplex virus 1.
... tegument proteins bound to capsids within these ...capsid proteins accumulate in assemblons suggests that assembly is facilitated by and is dependent on protein ...of proteins in- volved in ...
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Regulated Interaction of Tegument Proteins UL16 and UL11 from Herpes Simplex Virus
... that proteins in the tegument (located between the viral capsid and envelope proteins) play critical roles in the assembly and budding of ...herpesviruses. Tegument proteins UL16 and ...
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Human cytomegalovirus tegument proteins (pp65, pp71, pp150, pp28)
... HCMV tegument proteins pp65, pp71, pp150, and pp28 to understand how these proteins interact with the cell and function during the lytic cycle of HCMV ...HCMV tegument protein localization ...
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Analysis of the Interaction between the UL11 and UL16 Tegument Proteins of Herpes Simplex Virus
... UL16 tegument proteins of herpes simplex virus are conserved throughout the herpesvirus ...these proteins interact, perhaps to link UL16-bound nucleocapsids to UL11, which resides on the cytoplasmic ...
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Determination of Interactions between Tegument Proteins of Herpes Simplex Virus Type 1
... ment proteins (UL46, UL47, UL48, and UL49) have a struc- tural role in HSV-1 assembly also requires further investiga- ...major tegument proteins, UL46, UL47, UL48, and UL49, in PRV (12) can be ...
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Complex Formation between the UL16 and UL21 Tegument Proteins of Pseudorabies Virus
... different tegument proteins and a lipid envelope containing more than 10 different virally encoded membrane ...the tegument (30, ...of tegument (30, ...pesvirus tegument ...
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Interaction between the Human Cytomegalovirus Tegument Proteins UL94 and UL99 Is Essential for Virus Replication
... Based on our results, it appears that the interaction between UL94 and UL99 is required for each protein to traffic to the AC during infection. Analysis of the sequence requirements for traf- ficking of UL99 to the AC ...
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Interaction of Human Cytomegalovirus Tegument Proteins ppUL35 and ppUL35A with Sorting Nexin 5 Regulates Glycoprotein B (gpUL55) Localization
... UL35 proteins with sorting nexin ...UL35 proteins on the subcellular localization of CI-M6PR, HeLa cells were transfected with expression plasmids for EYFP-UL35 or EYFP- UL35A or for EYFP-UL82 as a ...
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Interaction Domains of the UL16 and UL21 Tegument Proteins of Herpes Simplex Virus
... viral proteins (33) even though its sequence lacks an obvious nuclear localization signal (data not ...viral proteins, cells that had been transfected for 18 h were infected with HSV for 16 h and then ...
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The Herpes Simplex Virus Type 1 UL17 Gene Encodes Virion Tegument Proteins That Are Required for Cleavage and Packaging of Viral DNA
... the tegument fraction of light particles, yielded the same mass ...the tegument fraction of light particles exhibited similar spectra, character- istic of the presence of the U L 17 and U L 46 ...
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Analysis of the Early Steps of Herpes Simplex Virus 1 Capsid Tegumentation
... which tegument proteins are present on these ...individual proteins and complexes typically can range from a few kDa to a few MDa and should be delayed and ...cytoplasmic proteins, exemplified ...
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Two Modes of Herpesvirus Trafficking in Neurons: Membrane Acquisition Directs Motion
... gD-GFP in extracellular viral particles, PK15 epithelial cells were transfected with full-length viral DNA encoding the RFP- cap/GFP-env virus and seeded on coverslips at low density. Viral particles subsequently ...
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Herpes Simplex Virus Utilizes the Large Secretory Vesicle Pathway for Anterograde Transport of Tegument and Envelope Proteins and for Viral Exocytosis from Growth Cones of Human Fetal Axons
... viral tegument and envelope proteins to the axon ter- minus and the possible mechanism(s) of virus assembly prior to exit from ...HSV-1 tegument and envelope proteins can travel in axons ...
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Organization of Capsid-Associated Tegument Components in Kaposi's Sarcoma-Associated Herpesvirus
... the tegument and, last, a lipid bilayer membrane called the ...inner tegument layers (5, 6). Upon cell entry, the outer tegument proteins are released into the host cell cytoplasm where some ...
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Herpesvirus Interactions with the Host Cytoskeleton
... alphaherpesvirus proteins in axons is a microtubule-dependent process and can be dis- rupted with nocodazole treatment (66, ...motor proteins (39, 96). It is largely unknown which viral proteins bind ...
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Human Cytomegalovirus pp28 (UL99) Localizes to a Cytoplasmic Compartment Which Overlaps the Endoplasmic Reticulum-Golgi-Intermediate Compartment
... different tegument proteins (including pp28) and three differ- ent envelope proteins of HCMV accumulated late in infection in a membranous, juxtanuclear structure which could not be colocalized to ...
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Mass Spectrometric Analyses of Purified Rhesus Monkey Rhadinovirus Reveal 33 Virion-Associated Proteins
... the proteins comprising the intact RRV ...these proteins may play essential roles in the establishment of viral infection, rather than or in addition to their involvement in structure and as- ...
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Dense Bodies of Human Cytomegalovirus Induce both Humoral and Cellular Immune Responses in the Absence of Viral Gene Expression
... viral tegument proteins and at least one nonstructural regula- tory protein have been shown to be dominant antigens for the generation of a cellular immune response against HCMV (7, 8, 34, 43, ...
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Phosphorylation of Structural Components Promotes Dissociation of the Herpes Simplex Virus Type 1 Tegument
... herpesvirus tegument is a stable macromolecular struc- ture formed by virion structural ...The proteins compris- ing this component of the virion are the first to be exposed to the intracellular environment ...
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