Th1 and Th2 balance
Nrf2 protects against pulmonary fibrosis by regulating the lung oxidant level and Th1/Th2 balance
... The present study showed that Nrf2 protects against the development of bleomycin-induced pulmonary inflam- mation and fibrosis by regulating the cellular redox level and Th1/Th2 balance. Nrf2 has an ...
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Distinct Effects of Anti-Tumor Necrosis Factor Combined Therapy on TH1/TH2 Balance in Rheumatoid Arthritis Patients
... immune balance in patients with rheumatoid arthritis (RA), a disease characterized by TH1 dominance, treated by the preferred combined anti-tumor necrosis factor (anti-TNF) and methotrexate (MTX) therapy ...
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An Overview of Leptin and the Th1/Th2 Balance
... Leptin participates in innate immunity by increasing the production of pro-inflammatory cytokines such as TNF-α, IL-6 and IL-12 in monocytes and macrophages, and by increasing the production of proangiogenic fac- tors ...
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Original Article Disrupted Th1/Th2 balance in patients with rheumatoid arthritis (RA)
... on Th1 cells but not Th2 cells. While Tim-3 down- regulates Th1 immunity and tolerance in vivo [7-9], blockade of Tim-3 exacerbated EAE as well as disease in the NOD model of Type I dia- betes ...
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Original Article Expression and clinical significance of Th1/Th2 cells in different HPV types of cervical cancer
... the Th1/Th2 balance of high-risk HPV-infected CC patients drifted to the Th2 direction, indicating that Th1 cells were decreased in patients with high-risk HPV- infected cervical ...of ...
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Expression of NOS–2, COX–2 and Th1/Th2 cytokines in migraine
... Abstract Nitric oxide (NO) proba- bly plays an important role in the pathogenesis of migraine without aura (MWA). As the activation of NO-ergic cascade has been shown to be closely linked to cyclooxyge- nase pathway and ...
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Immunomodulatory effect of Quercetin on dysregulated Th1/Th2 cytokine balance in mice with both type 1 diabetes and allergic asthma
... on Th1/Th2 immune balance, the Th1 and Th2 cytokines were estimated in BALF and serum samples collected post 1 hour of last Ova ...as Th1-mediated cytokine secretion and IL-4 and ...
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Original Article A correlation analysis of Th1/Th2 cells in preeclampsia patients
... the Th1/Th2 balance is disrupted, the maternal immune response enters a regulatory adaption ...of Th1/Th2 balance towards the Th1 immune response, a series of disor- ders ...
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THE FUNCTIONAL TH1 TH2 PARADIGM AMONG MULTIGRAVIDA WOMEN USING CONTRACEPTIVES
... The immunologic features of the multigravida women using contraceptives have shown functional shift from the TH1-TH2 balance towards TH1 function dominance. As well as shift from cytokine ...
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Effects of methylprednisolone combined with montelukast on immune function and cytokines in children with recurrent Henoch-Schonlein purpura
... Th1 and Th2 were the earliest discovered CD4+T cell subsets, and the balance of Th1/Th2 immune response has regulatory effects on humoral immune responses and cellular immune ...
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Distinct and Overlapping Effector Functions of Expanded Human CD4, CD8? and CD4CD8? Invariant Natural Killer T Cells
... the Th2 cytokines IL-4, IL-5 and IL-13 upon stimulation with a-GalCer presented by iDC or HeLa- CD1d cells or with PMA and ...of Th2 cytokine secretion by CD4 + iNKT cells is well documented ...
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TH1/TH2 Cytokine profile in relapsing-remitting multiple sclerosis patients treated with Glatiramer acetate or Natalizumab
... the Th1/Th2 balance by promoting a shift from the Th1 to the Th2 anti-inflammatory cytokine pathway ...some Th1/Th2 cyto- kines levels in plasma of RRMS patients treated ...
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Effects of stimulating interleukin -2/anti- interleukin -2 antibody complexes on renal cell carcinoma
... the Th1/Th2 balance in favor of Th1, and increased immune cell infiltration into tumor tissue in mice with RCC, all without inducing serious side effects such as pulmonary ...
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Th1/Th2 Cytokine Profile in Patients Coinfected with HIV and Leishmania in Brazil
... IL-13. Plasma samples were analyzed using the cytometric bead array human Th1/Th2 cytokine kit II (BD, San Jose, CA) (6). The limit of detection for this assay ranged from 2.6 pg/ml for IL-4, 2.8 pg/ml for ...
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Role of Th1/Th2 cytokines in the diagnosis and prognostic evaluation of ankylosing spondylitis.
... of Th1 cytokines, IFN-g and TNF-a, and Th2 cytokines, IL-4 and IL-10, in the 12 serum ...(Human Th1/Th2/Th17 Panel) (R&D, Minneapolis, MN, ...of Th1 and Th2 cytokines were ...
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Original Article Immune reaction of chronic nonbacterial prostatitis/pelvic pain syndrome and progress of treatment
... on Th1/Th2 cell function along with its clinical sig- nificance in autoimmune disease obtained rapid progress for illustrating pathological and physiological roles of Th1/Th2 cells, and ...
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Th1 and Th2 cytokines regulate proteoglycan specific autoantibody isotypes and arthritis
... Th1 and Th2 cytokines regulate PG-specific autoantibody IgG isotypes and susceptibility to arthritis. In the absence of IL-4, the production of PG-specific IgG2a isotype was dramatically enhanced and ...
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Difference in Cytokine Production and Cell Activation between Adenoidal Lymphocytes and Peripheral Blood Lymphocytes of Children with Otitis Media
... of Th1/Th2 cy- tokines, and the expression of CD69, one of the cell activation markers, were evaluated in adenoidal lymphocytes, compared with PBL, from children with ...
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The role of IFN gamma in systemic lupus erythematosus: a challenge to the Th1/Th2 paradigm in autoimmunity
... (and other cytokines) [15]. Moreover, IFN- γ secreted by Be1 cells and IL-4 secreted by Be2 cells, while presenting antigen to naïve T cells, regulated Th1 and Th2 develop- ment, respectively. In ...
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Original Article Human adipose tissue-derived mesenchymal stem cells ameliorate experimental autoimmune myasthenia gravis by modifying the balance of Th1/Th2/Th17/Treg cell subsets
... the balance of Th1, Th2, Th17, and Treg is associated with the development of EAMG ...specific Th1 and Th17 cells by inducing the gen- eration of AChR-specific Th2 and Treg ...
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