thalassaemia major
Providing a Cure for β Thalassaemia Major
... Providing a Cure for β Thalassaemia Major Providing a Cure for BThalassaemia MaJor L L Chan, FRCP, H P Lin, FRCP, W A Ariff"tn, FRCP, H Ariffm, MRCP, Department of Paediattics, Faculty of Medicine, Un[.] ...
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Distribution of serum lipids and lipoproteins in patients with beta thalassaemia major; an epidemiological study in young adults from Greece
... with major and minor beta thalassaemia and compared them with 112 healthy ...beta thalassaemia major from Italy found that these patients disclosed significantly lower total-cholesterol, ...
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Health related quality of life among children with transfusion dependent β-thalassaemia major and haemoglobin E β-thalassaemia in Sri Lanka: a case control study
... largest thalassaemia centres of Sri ...-thalassaemia major and haemoglobin E β -thalassaemia) aged 5 – 18 years were recruited as cases whilst a randomly selected group of children without ...
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Transfusion transmitted severe Plasmodium knowlesi malaria in a splenectomized patient with beta thalassaemia major in Sabah, Malaysia: a case report
... A 23-years old female presented to Pitas District Hospi- tal in northeast Sabah, Malaysia, with a 5-day history of fever, rigours, headache, and dizziness. She lived with her family in a malaria-endemic village ...
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Haplotype Analysis of β-Thalassaemia Major and Carriers with Filipino β-Deletion in Sabah, Malaysia
... β-thalassaemia major (β-TM) patients with homozygous Filipino β°-deletion and 157 carriers with heterozygous Filipino β°-deletion from 10 government hospitals in different regions of ...
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Ineffective Erythropoiesis: Associated Factors and Their Potential as Therapeutic Targets in Beta-Thalassaemia Major
... into thalassaemia major (also called Cooley anaemia), intermedia and minor, according to the disease’s ...severity. Thalassaemia major is fatal if untreated, and currently, the only therapy ...
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The efficacy of iron chelator regimes in reducing cardiac and hepatic iron in patients with thalassaemia major: a clinical observational study
... The aim of this study was to assess the efficacy of four available iron chelator regimes in 232 thalassaemia major patients by assessing the rate of change in repeated measurements of ca[r] ...
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Effects of combined deferiprone with deferoxamine on right ventricular function in thalassaemia major
... Background: Combination therapy with deferoxamine and oral deferiprone is superior to deferoxamine alone in removing cardiac iron and improving left ventricular ejection fraction (LVEF). The right ventricle (RV) is also ...
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Combined Oral and Parenteral Iron Chelation in Beta Thalassaemia Major
... Combined Oral and Parenteral Iron Chelation in Beta Thalassaemia Major ORIGINAL ARTICLE Combined Oral and Parenteral Iron Chelation in Beta Thalassaemia Maior K Balveer, MRCP*, K Pyar, FRCP*, B Wonke,[.] ...
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The social implications of thalassaemia major among Muslims of Pakistani origin: family experience and service delivery
... Prior to the study many health professionals attributed the low uptake rate of prenatal diagnosis for thalassaemia among British Pakistanis (table 3.1), and their attitude to the disease[r] ...
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Association between the Education and Thalassaemia: A Statistical Study
... disease. Thalassaemia is an inherited disorder in which there is an abnormality in one or more of the globin genes (Hong, ...general thalassaemia can be sub-divided into two groups: α-thalassaemia ...
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The social consequences of sickle cell and thalassaemia: improving the quality of support
... beta thalassaemia major (also known as thalassaemia major), about 65 per cent of whom are under eighteen years ...beta thalassaemia are people of Mediterranean and Southern European, ...
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Thalassaemia: A Study on The Perception of Patients and Family Members
... Although the small numbers of participants in focus groups limited the generalization of outcome to larger population, our study revealed several important findings. It is essential to note that participants in these ...
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Prevalence of β thalassaemia trait and Haemoglobin E disorders among students aged between 14-17yrs in Kurunegala district, Sri Lanka
... where thalassaemia rate is high, the incidence of thalassemia major has been reduced by public education, population screening, genetic counseling, and antenatal diagnosis ...a thalassaemia screening ...
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A Review of Endocrine Disorders in Thalassaemia
... Thalassaemia major is a hereditary disorder of haemog- lobin synthesis and the homozygous state results in se- vere ...of thalassaemia but determining the exact prevalence is difficult because of ...
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KAP STUDY GENETIC DISORDER Frequency of carrier screening and preventive orientation among first degree relatives of Thalassaemia patients
... of thalassaemia major in future generations and not feed the stigma of genetic diseases on affected ...of thalassaemia in future family ...on thalassaemia which focused on Khyber Pakhtunkhwa ...
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Identification and key management of non-transfusion-dependent thalassaemia patients: not a rare but potentially under-recognised condition
... HU, as an inducer of HbF, has been tested in patients with β-thalassaemia major, β-thalassaemia intermedia and HbE/β-thalassaemia. This compound affects stem cell dif- ferentiation in the bone ...
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Detection of red cell alloantibodies in thalassaemia patients
... Results: Out of 106 β-thalassaemia major patients included in the study, 7.5% of patients developed alloantibodies, all being clinically significant. The alloantibodies were anti-E, anti c, anti e and ...
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Value of black blood T2* cardiovascular magnetic resonance
... Beta thalassaemia major (TM) is an inherited anaemia and without regular blood transfusions patients die dur- ing childhood. Although transfusions improve health and survival, the consequent tissue iron ...
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Epistasis and the sensitivity of phenotypic screens for beta thalassaemia
... beta thalassaemia screens using OTOFTs still bet- ter than nothing? The studies summarized in Table III dem- onstrate that sensitivities of over 90% are possible in specific populations, and the authors of these ...
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