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thalassemia major

Study on Clinical Profile of Beta Thalassemia Major Children

Study on Clinical Profile of Beta Thalassemia Major Children

... Beta thalassemia represents group of recessively inherited hemoglobin disorders characterized by reduced synthesis of β globin chains resulting in severe anemia which needs repeated blood ...

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Iron overload in beta thalassemia major patients

Iron overload in beta thalassemia major patients

... beta thalassemia major under any chelation ...beta thalassemia major was confirmed either by hemoglobin electrophoresis profiles or ...

8

Comparison of Body Mass Index in Beta Thalassemia Major Patients with That of Normal Subjects

Comparison of Body Mass Index in Beta Thalassemia Major Patients with That of Normal Subjects

... The study design involved total 216 individuals who were divided into two groups of 100 normal subjects (control group) and 116 patients of beta thalassemia major (study group) receiving regular blood ...

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Prevalence of skeletal changes in patients with b thalassemia major in mosul

Prevalence of skeletal changes in patients with b thalassemia major in mosul

... of thalassemia major: -Thalassemia is characterized by chronic hemolytic anemia which becomes manifest later in infancy but not in the ...with thalassemia major is probably ...

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Frequency of Celiac Disease in Children with Beta Thalassemia major

Frequency of Celiac Disease in Children with Beta Thalassemia major

... also non-gastrointestinal features by which patients with celiac disease may present. These manifestations include iron deficiency with or without anemia of otherwise unknown origin, recurrent abdominal pain misdiagnosed ...

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Awareness about thalassemia and feasibility of cascade screening in families of thalassemia major patients

Awareness about thalassemia and feasibility of cascade screening in families of thalassemia major patients

... thalassemia major at a tertiary care center in Mumbai which is a government run major hospital in ...with thalassemia major who consented were included in the ...of thalassemia ...

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Hyperferritinemia and oxidative stress in the kidney of beta thalassemia major

Hyperferritinemia and oxidative stress in the kidney of beta thalassemia major

... 4. Chiou SS, Chang TT, Tsai SP, Jang RC, Lin SK, Lee SC, Tsai SM, Tsai LY. Lipid peroxidation and antioxidative sta- tus in β-thalassemia major patients with or without hepati- tis C virus infection. Clin ...

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Serum Antioxidant Levels in Children with Beta-Thalassemia Major

Serum Antioxidant Levels in Children with Beta-Thalassemia Major

... Cu is present largely in the form of organic complexes, many of which are metalloproteins acting as enzymes. In our study serum Cu level was found to be significantly increased in patients when compared with controls ...

5

A study of echocardiographic changes in patients of thalassemia major

A study of echocardiographic changes in patients of thalassemia major

... Thalassemia major patients were compared to normal healthy children for various parameters in echocardiographic changes. These parameters were: diastolic and systolic pulmonary artery pressure, ventricular ...

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Effect of Pamidronate on Osteoporosis in Patients with β-Thalassemia Major

Effect of Pamidronate on Osteoporosis in Patients with β-Thalassemia Major

... Patients and Methods: This cross sectional study was conducted on 20 patients with β-thalassemia major with osteoporosis. Patients received Pamidronate injections (30 mg in equal intervals of one month) for ...

5

Detection of Alloantibodies in Multiply Transfused Thalassemia Major Patients.

Detection of Alloantibodies in Multiply Transfused Thalassemia Major Patients.

... with thalassemia major and sickle cell disease, should have their extended red cell antigen phenotype (ABO, Rh, Kell, Kidd, Duffy, Lewis, and MNSs blood group systems) determined before they start ...

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Treating thalassemia major-related iron overload: the role of deferiprone

Treating thalassemia major-related iron overload: the role of deferiprone

... for thalassemia major has improved to the point where we predict that patients’ life expectancy will approach that of the normal ...Keywords: thalassemia, iron overload, iron chelation therapy, ...

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Ayurveda therapy for thalassemia major (beejadushtijanyapandu) as  an adjuvant – a case study

Ayurveda therapy for thalassemia major (beejadushtijanyapandu) as an adjuvant – a case study

... to the World Health Organization (WHO) is a genetically passed down blood disorder disease in which body makes an abnormal form of haemoglobin due to defects in the globin chain. i This causes early excessive destruction ...

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Evaluation of marriage and childbirth in patients with non-transfusiondependent beta thalassemia major at Thalassemia Research Center of Sari, Iran

Evaluation of marriage and childbirth in patients with non-transfusiondependent beta thalassemia major at Thalassemia Research Center of Sari, Iran

... With respect to the pregnancy outcomes in thalassemia major patients, there were 23 pregnancies reported within a marriage period of 25 years in the present study. In one study, Ansari et al. reported 62 ...

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Serum Dickkopf-1 and Correlation with Bone Mineral Density in Patients with Beta Thalassemia Major in North-Eastern of Iran

Serum Dickkopf-1 and Correlation with Bone Mineral Density in Patients with Beta Thalassemia Major in North-Eastern of Iran

... Beta-thalassemia syndromes are a family of inherited disorders associated with decreased or absent globin chains production; it leads to hemoglobin reduction in red blood cells and anemia [1]. Osteoporosis is a ...

7

Anaesthetic Management in an Adult Thalassemia Major Patient  Undergoing Splenectomy: A Case Report

Anaesthetic Management in an Adult Thalassemia Major Patient Undergoing Splenectomy: A Case Report

... Thalassemia major is a common form of haemoglobinopathy in developing countries like ours and many times it present with clinically challenging situations with difficult ...with thalassemia ...

5

Heterozygous Beta Thalassemia in Parents of Children with Beta Thalassemia Major

Heterozygous Beta Thalassemia in Parents of Children with Beta Thalassemia Major

... A total of 100 families of known thalassemia major children were selected whose parents and grand parents (both maternal and paternal) were alive. They belonged to district Peshawar. All were thoroughly ...

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Prothrombotic markers in Thalassemia major patients: A paradigm shift

Prothrombotic markers in Thalassemia major patients: A paradigm shift

... Background: It is being increasingly recognised that thalassemia major patients, like intermedia, have increased propensity for thromboembolism. Deficiency of natural anticoagulants is more recently defined ...

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Hepcidin and HFE Polymorphisms and Ferritin Level in β-Thalassemia Major

Hepcidin and HFE Polymorphisms and Ferritin Level in β-Thalassemia Major

... Background: Thalassemia patients need repeated transfusion that lead to increased blood ferritin level and iron overload in the heart and ...beta thalassemia major ...

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Treatment Status of Patients with Β-Thalassemia Major in Northern Iran: Thalassemia Registry System

Treatment Status of Patients with Β-Thalassemia Major in Northern Iran: Thalassemia Registry System

... In addition to iron chelators, patients with thalas- semia take different drugs. This article has only investigated general drugs but not specific drugs used for the treatment and control of complica- tions. To prevent ...

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