The arcuate nucleus
Glucokinase activity in the arcuate nucleus regulates glucose intake
... the arcuate nucleus, ventromedial nucleus (VMN), paraventricular nucleus (PVN), and lateral hypotha- lamic area (LHA), which regulate energy homeostasis and are part of a CNS glucose-sensing ...
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Antagonistic modulation of NPY/AgRP and POMC neurons in the arcuate nucleus by noradrenalin
... the arcuate nucleus of the hypothalamus (ARH) satiety signaling (anorexigenic) pro- opiomelanocortin (POMC)-expressing and hunger signaling (orexigenic) agouti-related peptide (AgRP)-expressing neurons are ...
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Should We Make More Bone or Not, As Told by Kisspeptin Neurons in the Arcuate Nucleus.
... ► bone Abstract Since its initial discovery in 2002, the neuropeptide Kisspeptin (Kiss1) has been anointed as the master regulator controlling the onset of puberty in males and females. Over the last several years, ...
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The arcuate nucleus mediates GLP 1 receptor agonist liraglutide dependent weight loss
... glucose, liraglutide also reduces body weight. It is not fully understood how liraglutide induces weight loss or to what degree liraglutide acts directly in the brain. Here, we determined that liraglutide does not ...
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Undernutrition Reduces Kisspeptin and Neurokinin B Protein Expression in the Arcuate Nucleus of Young, Male Sheep.
... the arcuate nucleus (ARC) of the hypothalamus express kisspeptin and neurokinin B (NKB), both of which have been shown to play key stimulatory roles in the generation of GnRH/LH pulses, we hypothesized that ...
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Mapping neuronal inputs to Kiss1 neurons in the arcuate nucleus of the mouse.
... into arcuate (ARC) Kiss1 ...to arcuate Kiss1 neurons includ- ing proopiomelanocortin neurons in the ARC itself, kisspeptin neurons in the anteroventral periventricular nucleus, vasopressin neurons in ...
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Remodeling of the arcuate nucleus energy balance circuit is inhibited in obese mice
... hypothalamic arcuate nucleus (ARN) energy-balance circuit plays a key role in regulating body ...the arcuate neuronal circuitry in the mouse and reveal the unexpected capacity of diet and leptin ...
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Glucose sensing in the hypothalamic arcuate nucleus: electrophysiological and mathematical studies
... 3.1 Electrophysiology - Whole-cell patch-clamp: The arcuate nucleus 3.1.1 Experimental groups and animal care Male Wistar rats, aged 5 to 8 weeks old, were used throughout this study. All experiments were ...
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Ultrastructural response of arcuate nucleus neurons to fasting in aged rats
... The arcuate nucleus of the hypothalamus (ARH) is involved in the control of energy homeostasis. Leptin — an adipocyte derived hormone — is known to act on the hypothalamic nuclei and thus to control body ...
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The effect of fasting on the ultrastructure of the hypothalamic arcuate nucleus in young rats
... occur commonly in the ventrolateral part of the ven- tromedial nucleus (VMN) in normal female rats, pre- suming that they might be involved in the synthe- sis of luteinizing hormone-releasing hormone. As re- ...
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Hypoplasia of Medullary Arcuate Nucleus in Unexpected Late Fetal Death (Stillborn Infants): A Pathologic Study
... S tillbirth is defined as late fetal death before the complete expulsion or retraction of the fetus from the mother. 1 Advances in maternal and fetal care have produced a significant reduction in perinatal mortality but ...
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Metabolic and serotonergic modulation of hypothalamic arcuate nucleus neurones in vitro
... Bath application of 5-HT induced a membrane depolarisation in a sub-population of ARC neurones (30%), a response that persisted in the presence of TTX indicating a direct eftect.. 5-[r] ...
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The electrophysiological and morphological characterisation of aminergic responsive neurones within the rat hypothalamic arcuate nucleus in vitro
... therefore the classification of Arc neurones represent the spectrum of electrophysiological neuronal populations present within this nucleus. The differences in expression of ion channels and neuronal activity ...
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The LIM homeobox transcription factor Isl1 plays crucial roles in the development of multiple arcuate nucleus neurons
... several arcuate neuronal subpopulations: the orexigenic neuropeptides AgRP and NPY of AgRP-neurons, the anorexigenic neuropeptide α MSH of POMC- neurons, and the growth stimulatory peptides GHRH of GHRH- neurons ...
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Effects of Hypothalamic Arcuate Nucleus NPY5 Receptor Signaling Pathway on Feeding Regulation in Normal Rats and Obesity Rats
... hypothalamic arcuate nucleus (ARC) in normal rats and obesity rats, and the effect of the NPY5 receptor agonist [D-Trp34] NPY and NPY5 Receptor antagonist CGP-71683 on Food Intake in the normal and obesity ...
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Original Article Expression of kisspeptin-GnRH system is down-regulated in hypothalamic arcuate nucleus of male rats with high-fat-diet
... [19] Levin BE. Arcuate NPY neurons and energy ho- meostasis in diet-induced obese and resistant rats. Am J Physiol 1999; 276: R382-387. In conclusion, we believe that obesity leads to a series of changes in the ...
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Transplantable rat glucagonomas cause acute onset of severe anorexia and adipsia despite highly elevated NPY mRNA levels in the hypothalamic arcuate nucleus
... The MSL-G-AN–bearing animals, however, display levels of cir- culating glucocorticoids within the normal range, and plasma insulin levels significantly lower than animals without tumors. Thus, despite similar ...
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Heavy flavors in nucleus-nucleus and proton-nucleus collisions
... Abstract. A multi-step setup for heavy-flavor studies in high-energy nucleus-nucleus (AA) and proton-nucleus (pA) collisions is presented. The propagation of the heavy quarks in the medium is ...
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The Fragmentation Region of High Energy Nucleus-Nucleus and Hadron-Nucleus Collisions
... N B /N gluon ∼ cons (13) that is indepdnent of beam energy. 4 The Ba-Glasma We shall refer to this baryon rich matter produced in the fragmentation region of the collision of two ultra-relativistic nuclei as the ...
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Simulation of neutron production in hadron-nucleus and nucleus-nucleus interactions in Geant4
... in nucleus - nu- cleus interactions at projectile energy 1 – 2 GeV per nucleon ...the nucleus-nucleus interac- tions at high and very high ...
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