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The fear extinction model

Contextual Fear Extinction and Re Extinction in Carioca High  and Low Conditioned Freezing Rats

Contextual Fear Extinction and Re Extinction in Carioca High and Low Conditioned Freezing Rats

... long extinction and reacquisition of contextual fear memories in rats selectively bred for high (CHF) and low (CLF) contextual conditioned ...long extinction training reduced the expression of ...

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Molecular mechanisms of D-cycloserine in a fear extinction posttraumatic stress disorder (PTSD) animal model

Molecular mechanisms of D-cycloserine in a fear extinction posttraumatic stress disorder (PTSD) animal model

... associative fear component, while those symptoms not associated with the traumatic memory ...(associative fear) display conditioned responses, and that these conditioned (fearful) responses are also ...

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Effects of Systemic Administration of Oxytocin on Contextual Fear Extinction in a Rat Model of Post-Traumatic Stress Disorder

Effects of Systemic Administration of Oxytocin on Contextual Fear Extinction in a Rat Model of Post-Traumatic Stress Disorder

... Oxytocin (OXT), a nine-amino acid peptide, is synthe- sized in the hypothalamus and secreted into the blood stream in the neurohypophysis as a neuro-hormone (Gimpl & Fahrenholz 2001). As a hormone, it mainly ...

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Bilateral Alternating Auditory Stimulations Facilitate Fear Extinction and Retrieval

Bilateral Alternating Auditory Stimulations Facilitate Fear Extinction and Retrieval

... of fear conditioning, its extinction and its retrieval are at the core of posttraumatic stress disorder ...especially fear extinction delay, disappear after alternating bilateral stimulations ...

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Behavioral and Neurobiological Assessments of Predator Based Fear Conditioning and Extinction

Behavioral and Neurobiological Assessments of Predator Based Fear Conditioning and Extinction

... and Extinction Testing. Context and cued fear memory tests occurred 21, 28 and 35 days after ...potentially model intrusive traumatic memories that occur at great delays following a traumatic ...On ...

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Moderators of the relationship between fear extinction learning and posttraumatic stress disorder

Moderators of the relationship between fear extinction learning and posttraumatic stress disorder

... conceptual model hold true, these findings carry important ...this extinction-based model of PTSD and other fear-related disorders, we suggest a number of research ...(including fear ...

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The Effect of catastrophic cognitions on fear acquisition and extinction in posttraumatic stress disorder

The Effect of catastrophic cognitions on fear acquisition and extinction in posttraumatic stress disorder

... 42 Theoretical and Clinical Implications Catastrophic thinking in PTSD. Partially in support of cognitive theory, the present study found that catastrophic thinking in the PTSD group was significantly greater than ...

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Transcutaneous vagus nerve stimulation and extinction of prepared fear: A conceptual nonreplication

Transcutaneous vagus nerve stimulation and extinction of prepared fear: A conceptual nonreplication

... the extinction of conditioned ...the extinction phase compared to participants in the sham ...GUTS model of anxiety, which posits that the vagus nerve plays an integral part in recognizing safety ...

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Minocycline attenuates interferon-α-induced impairments in rat fear extinction

Minocycline attenuates interferon-α-induced impairments in rat fear extinction

... Our results also show that astrocytes were activated by infusing IFN- α into the amygdala. Astrocytes are the major glial cell population in the CNS and are active participants in propagating and regulating neuroinflam- ...

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Intolerance of uncertainty predicts fear extinction in amygdala-ventromedial prefrontal cortical circuitry

Intolerance of uncertainty predicts fear extinction in amygdala-ventromedial prefrontal cortical circuitry

... Electrodermal recordings were obtained using ADInstru- ments (ADInstruments Ltd., Chalgrove, Oxfordshire) hard- ware and software. An ML138 Bio Amp connected to an ML870 PowerLab Unit Model 8/30 amplified the EDA ...

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Fear extinction learning improvement in PTSD after EMDR therapy: an fMRI study

Fear extinction learning improvement in PTSD after EMDR therapy: an fMRI study

... the extinction learning, since they could be faster to per- form the fear evaluation task and perhaps more auto- mated when extinction is better ...the fear extinction learning. ...

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Delay and trace fear conditioning in a complex virtual learning environment - neural substrates of extinction

Delay and trace fear conditioning in a complex virtual learning environment - neural substrates of extinction

... that extinction of delay and trace fear conditioning is associated with activations of the amygdala and the vmPFC as well as involvement of the insular and the anterior cingulate cortices and the ...One ...

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The impact of sex differences on fear extinction and extinction recall

The impact of sex differences on fear extinction and extinction recall

... Percent fear recovery in the late phase for CS+ in males and ...impaired fear extinction (Graham & Milad, 2013) by comparing SCR during fear conditioning, fear extinction, and ...

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Sex differences in fear conditioning and extinction

Sex differences in fear conditioning and extinction

... On the other hand, the greater threat expectancy ratings by females compared to males during the acquisition phase was further examined and, sex was not a significant predictor of th[r] ...

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Requirement for BDNF in the Reconsolidation of Fear Extinction

Requirement for BDNF in the Reconsolidation of Fear Extinction

... of extinction memory, it would be too sim- plistic to talk about BDNF as a “consolidation” or a “reconsoli- dation” ...of extinction memory after its reacti- ...

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The role of mediodorsal thalamic nucleus in fear extinction

The role of mediodorsal thalamic nucleus in fear extinction

... of fear extinction impaired by lesions of the ven- tral mPFC (vmPFC-PrL and IL), a role of the vmPFC in fear extinction has been discovered (Morgan et ...of extinction but on ...

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The effect of menstrual phase on fear extinction learning and recall

The effect of menstrual phase on fear extinction learning and recall

... during extinction learning substantiates the view that discrepancies between these groups are a consequence of poor extinction memory ...reduced extinction recall when the original CS + is presented ...

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On the transition from reconsolidation to extinction of contextual fear memories.

On the transition from reconsolidation to extinction of contextual fear memories.

... trigger extinction. In appetitive and fear cued Pavlovian memories, an intermediate “null point ” period has been observed where neither process seems to be ...contextual fear memory. Adult rats were ...

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On the transition from reconsolidation to extinction of contextual fear memories

On the transition from reconsolidation to extinction of contextual fear memories

... trigger extinction. In appetitive and fear cued Pavlovian memories, an intermediate “null point ” period has been observed where neither process seems to be ...contextual fear memory. Adult rats were ...

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The effect of ketamine on the consolidation and extinction of contextual fear memory

The effect of ketamine on the consolidation and extinction of contextual fear memory

... the extinction of contextual fear memory. Pre- extinction ketamine , at both doses, led to the maintenance of conditioned response even when ketamine was re-administered prior to the recall trial, ...

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