The growth cone
The dynamics of growth cone morphology
... extract growth cone outlines, a quadrilateral region of interest was manually placed over the growth cone for selected frames of each movie and then automatically interpo- lated for ...
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Electrical activity, growth cone motility and the cytoskeleton
... in growth cone motility after electrical stimulation are accompanied by an influx of calcium through voltage-sensitive calcium ...on growth cone morphology are not the same for all ...Some ...
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in Neurite Outgrowth and Growth Cone Turning during Regeneration
... 9 1.06 The Role of Retinoic Acid in Axon Guidance The guidance of neurites to their appropriate targets is accomplished by dynamic structures called growth cones, located at the tips of extending neurites. These ...
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Homer regulates calcium signalling in growth cone turning
... gradients, whereby a large change in [Ca ++ ] i activates CaM- KII and subsequent attraction. Alternatively, a small change in [Ca ++ ] i activates CaN and subsequent repulsion [8]. The cyclic nucleotides work in concert ...
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Regulation of ECM degradation and axon guidance by growth cone invadosomes
... neuronal growth cones form protrusions that share molecular, structural and functional characteristics of ...invadosomes. Growth cones from all neuron types and species examined, including a variety of ...
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Agrin regulates growth cone turning of Xenopus spinal motoneurons
... mammalian growth factors, PI3-kinase is a crucial component of the initial cytoplasmic signaling ...agrin-induced growth-cone ...the growth-cone ...
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Cytoskeletal Dynamics and Transport in Growth Cone Motility and Axon Guidance
... the growth cone and the transitional (T) domain, a band of the growth cone at underlying dynamic cytoskeletal structures (neurofi- the interface of the P domain and the central (C) domain; ...
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Axon guidance receptors direct growth cone pathfinding: rivalry at the leading edge
... the growth cone at any given point in time and space, the integration of ensuing signal transduction cascades is necessary to achieve a synchronous response to the extracellular ...
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Protein synthesis dependence of growth cone collapse induced by different Nogo-A-domains
... axon growth in the developing and mature nervous system, and this is carried out by two distinct domains in the protein, Nogo-A-Δ20 and Nogo- ...axon growth cones by these domains are not well ...
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Mobility and cycling of synaptic protein–containing vesicles in axonal growth cone filopodia
... neuronal growth cone filopodia are mostly devoid of ...the growth cone, “as if somehow excluded from the peripheral regions of the growth cone, particularly the filopodia and ...
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RPM 1 regulates axon termination by affecting growth cone collapse and microtubule stability
... PLM growth cones were collected using a Leica SP8 confocal microscope under 63× magnification and 2× ...necessary. Growth cones were considered dynamic if at least one distinct membrane protrusion extended ...
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Growth cone-specific functions of XMAP215 in restricting microtubule dynamics and promoting axonal outgrowth
... in growth cones that accounts for the velocity change? Given the current understanding of XMAP215 activity, one simple hypothesis was that XMAP215, which contains multiple tubulin dimer-binding TOG domains, might ...
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How does calcium interact with the cytoskeleton to regulate growth cone motility during axon pathfinding?
... where growth cones guide axons through the embryonic environment to connect with their appropriate synaptic partners to form functional ...the growth cone cytoskeleton and hence motility, remain ...
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Mild and repetitive very mild axonal stretch injury triggers cystoskeletal mislocalization and growth cone collapse
... in growth cones was similar to the growth cones in normal developing distal ...in growth cones and the proportion of collapsed growth cones significantly increased at 72 h PI when compared ...
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Effects of Lithium on Axonal Growth Cone Area
... surprising, seeing that multiple papers on the subject have found the opposite result (Williams et al, 2004; Williams et al, 2002; Shaltiel et al, 2007). Possibilities for why these results were received could be due to ...
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Growth cone navigation in substrate bound ephrin gradients
... Growth cone navigation in substrate-bound ephrin gradients Anne ...how growth cones read gradients of membrane-bound guidance ...spacings. Growth cones of chick temporal retinal axons are able ...
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Trade Liberalization, Economic Growth, and Income Distribution in a Multiple-cone Neoclassical Growth Model
... to growth depends on the kind of good that is ...tivity growth whereas Frankel and Romer (1999) and Rodriguez and Rodrik (2000) examined the effe
ts on per apita gross domesti produ
t (GDP) ...
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Homer, TRP channels and calcium : the signalling triad of growth cone motility
... Indeed, single wavelength calcium imaging experiments showed that Homer morphant DRGs exhibited altered calcium responses to BDNF microgradients and a higher frequency of TRPC-mediated[r] ...
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A preliminary investigation into the growth of the Sisters scoria cone complex, Ascension Island.
... scoria cone complex (SSCC) in the north of the island, which is composed of at least 4 scoria cones, tephra fall deposits and ...scoria cone complex was also undertaken in an attempt to correlate the lava ...
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Substrate interactions affecting motor growth cone guidance during development and regeneration
... Following crush injuries, growth cones enter their original fascicles in the distal nerve stump whereas following cut injuries the regenerating axons are more likely to encounter inappro[r] ...
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