The insulin-like growth factor system
The insulin-like growth factor system in multiple myeloma: diagnostic and therapeutic potential
... the insulin/IGF system and/or downstream signaling ...and insulin/IGF-IR targeting was shown to resensitize the MM cells ...different growth factors (including IGF-I and TGFß) and protect the ...
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Acute effects of physical exercise on the serum insulin like growth factor system in women with fibromyalgia
... Serum insulin-like growth factor-1 (S-IGF-1) has been noted after physical activity in healthy subjects, while the acute release of S-IGF-1 in relation to exercise has not previously been ...
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The growth hormone (GH) insulin-like growth factor
... with insulin levels. The association between IGF-1 and insulin may reflect the effect of insulin to increase hepatic IGF-1 production, 35 or circulating levels of both hormones may be determined by ...
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Insulin-like Growth Factor Binding Proteins.pdf
... muscle cells secrete a serine protease for insulin like growth insulin-like growth factor binding proteins 1 and 3 on. factor binding protein-2[r] ...
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Gene expression patterns of insulin-like growth factor 1, insulin-like growth factor 2 and insulin-like growth factor binding protein 3 in human placenta from pregnancies with intrauterine growth restriction
... Umbilical cord blood sampling In 27 pregnancies with IUGR and 32 pregnancies without, 10 mL blood samples were obtained from the umbilical cord to test glucose and insulin levels. Blood sampling was performed ...
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Insulin like growth factors and insulin like growth factor binding proteins in mammary gland function
... A model thus emerges where, during pregnancy and lacta- tion, GH increases IGF-I synthesis and prolactin represses IGFBP-5 synthesis to maximize the survival and prolifera- tive effects of IGF-I. Following weaning, ...
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The Role of Insulin-like Growth Factor 1 and Insulin-like Growth Factor Binding Protein 3 in Human Esophageal Cancer
... Background: Insulin-like growth factors (IGF-1) and insulin-like growth factor binding protein-3 (IGFBP-3) play important roles in cell growth and ...
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Growth hormone and insulin like growth factor I in odontogenesis
... Int J Be\' Hiol 39 263 272 (1995) 263 Growth hormone and insulin like growth factor I in odontogenesis WilLIAM GEORGE YOUNG' Department of Dentistry, The University of Queensland, Australia ABSTRACT T[.] ...
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The insulin and insulin-like growth factor receptor family in neoplasia: an update
... the insulin receptor, but also of other receptor tyrosine ...with insulin signal- ling, and thus with carbohydrate metabolism ...tissue growth factors, insulin and IGF signalling have major ...
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Insulin like growth factor 1 stimulation of lymphopoiesis
... We show that treatment of adult mice with recombinant human insulin-like growth factor 1 (rhIGF-1) induces striking modifications in lymphocyte number and function. 9-mo-old male mice received ...
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Insulin like growth factor 1, insulin like growth factor binding protein 3 and lobule type in the Nurses' Health Study II
... of insulin-like growth factors in the microscopic anatomy of the breast lobules, further research is needed to elucidate the relationship between hormones, such as IGF-1 and IGFBP-3, and age-related ...
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Statins inhibit insulin-like growth factor action in first trimester placenta by altering insulin-like growth factor 1 receptor glycosylation
... E-mail: [email protected] Submitted on June 19, 2014; resubmitted on September 8, 2014; accepted on October 3, 2014 abstract: The rapid rise in obesity, metabolic syndrome and type 2 diabetes is one of ...
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Antepartal insulin-like growth factor 1 and insulin-like growth factor binding protein 2 concentrations are indicative of ketosis in dairy cows
... Antepartal insulin-like growth factor 1 and insulin-like growth factor binding protein 2 concentrations are indicative of ketosis in dairy cows Piechotta, M ; ...
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Adult growth hormone deficiency treatment with a combination of growth hormone and insulin like growth factor 1 resulting in elevated sustainable insulin like growth factor 1 and insulin like growth factor binding protein 3 plasma levels: a case report
... At this juncture one of us (ERB) considered the use of Increlex® (a mecasermin (rDNA origin) injection). This agent is an aqueous solution for injection containing human insulin-like growth ...
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Investigation of insulin like growth factors/insulin like growth factor binding proteins regulation in metabolic syndrome patients
... in patients with MSx and their relationship with clinical parameters of the disease. As shown in Table 1, MSx patients had lower levels of IGF-1, IGFBP-1, and IGFBP-2 compared with healthy subjects. Notably, compared ...
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Switching to fast growth: the insulin like growth factor (IGF) system in skeletal muscle of Atlantic salmon
... model system to study the regulation of muscle growth in ...zero growth and are then fed to satiation with a high protein ...IGF system including retained paralogues, and examine gene ...
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Insulin and insulin like growth factor II endocytosis and signaling via insulin receptor B
... The endocytosis of IGF-II by IR-B exhibited to pro- ceed with a faster kinetics than that of insulin measured both by confocal microscopy and flow cytometry. These techniques showed to be complementary since ...
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Effects of insulin like growth factor I on glucose tolerance, insulin levels, and insulin secretion
... to insulin. The lowered area under the insulin curve during oGTT and MTT as a result of the administration of rhIGF-I were related to the fasting insulin levels during saline infusion (oGTT: r = ...
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Epithelial-to-mesenchymal transition in breast cancer: a role for insulin-like growth factor I and insulin-like growth factor–binding protein 3?
... transcription factor, Snail, that is key to effecting ...transcription factor involved in EMT, to induce invasion of MDA–MB-231 ...by insulin and found that a key transcription factor ...
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Insulin-Like Growth Factor-1 in Acute Ischemic Stroke
... Discussion Our study revealed that serum IGF-1 levels were signifi- cantly reduced in cases of first AIS compared to con- trols. For the entire group, after adjusting other possible risk factors, a reduced IGF-I level ...
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