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The Oxytocin Receptor

Association between the oxytocin receptor (OXTR) gene and mesolimbic responses to rewards

Association between the oxytocin receptor (OXTR) gene and mesolimbic responses to rewards

... the oxytocin receptor (OXTR) gene confer small but significant risk for ASDs for which the underlying mechanisms may involve associations between variability in oxytocin signaling pathways and neural ...

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Evidence that genetic variation in the oxytocin receptor (OXTR) gene influences social cognition in ADHD

Evidence that genetic variation in the oxytocin receptor (OXTR) gene influences social cognition in ADHD

... the oxytocin receptor (OXTR) gene and autism: relationship to Vineland Adaptive Behavior Scales and ...the oxytocin receptor (OXTR) gene polymorphisms with autism spectrum disorder (ASD) in ...

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The oxytocin receptor gene predicts brain activity during an emotion recognition task in autism

The oxytocin receptor gene predicts brain activity during an emotion recognition task in autism

... the oxytocin receptor ( OXTR ) gene, as it has been previously linked with social cognition and behaviour in the typical population, as well as with autism ...[16]. Oxytocin (OXT) is a nonapep- tide ...

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Does the oxytocin receptor polymorphism (rs2254298) confer 'vulnerability' for psychopathology or 'differential susceptibility'? insights from evolution

Does the oxytocin receptor polymorphism (rs2254298) confer 'vulnerability' for psychopathology or 'differential susceptibility'? insights from evolution

... D4 receptor gene indicate that the early environment plays a crucial role in the development of favourable versus unfavourable ...the oxytocin receptor ...the oxytocin receptor gene ...

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Investigation of the oxytocin receptor gene in sheep

Investigation of the oxytocin receptor gene in sheep

... 5.3 Northem hybridization analysis of ovine pituitary gland OTR mRNA expression during the estrous cycle and detection of OTR gene expression in coipus luteum.. Lane 1-17 pituitary gla[r] ...

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The association of childhood maltreatment with depression and anxiety is not moderated by the oxytocin receptor gene

The association of childhood maltreatment with depression and anxiety is not moderated by the oxytocin receptor gene

... application of genetically informed treatments with regard to the oxytocin system still remain to be elucidated. Conclusions In sum, while the OXTR gene has been found to play a role in social processes and ...

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Genetic variation in the oxytocin receptor (OXTR) gene is associated with Asperger Syndrome

Genetic variation in the oxytocin receptor (OXTR) gene is associated with Asperger Syndrome

... for oxytocin (OXT) and oxytocin receptor (OXTR) genes in social-emotional behaviors, and several studies indicate that the oxytocin/oxytocin receptor system is altered in ...

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Genetic variation in the oxytocin receptor (OXTR) gene is associated with Asperger Syndrome

Genetic variation in the oxytocin receptor (OXTR) gene is associated with Asperger Syndrome

... for oxytocin (OXT) and oxytocin receptor (OXTR) genes in social-emotional behaviors, and several studies indicate that the oxytocin/oxytocin receptor system is altered in ...

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Association between genetic variation in the oxytocin receptor gene and emotional withdrawal, but not between oxytocin pathway genes and diagnosis in psychotic disorders

Association between genetic variation in the oxytocin receptor gene and emotional withdrawal, but not between oxytocin pathway genes and diagnosis in psychotic disorders

... that oxytocin-related genes are not main contributors to the risk of developing schizophrenia or other psychotic disorders, but support the notion that specific variation in the OXTR gene might play a role in the ...

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Expression and activation of the oxytocin receptor in airway smooth muscle cells: Regulation by TNFα and IL-13

Expression and activation of the oxytocin receptor in airway smooth muscle cells: Regulation by TNFα and IL-13

... that oxytocin induced airway smooth muscle contraction and that cytokines increased expression of the receptor, we characterized whether BAL fluid derived from healthy subjects as well as sub- jects with ...

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The oxytocin receptor antagonist, Atosiban, activates pro inflammatory pathways in human amnion via Gαi signalling

The oxytocin receptor antagonist, Atosiban, activates pro inflammatory pathways in human amnion via Gαi signalling

... the receptor (possibly via phosphorylation) to a non-active conforma- tional state (Gether et ...tocolytic. Oxytocin receptor antagonists that inhibit both OT induced contractions and in fl ammation ...

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The Oxytocin Receptor Gene (OXTR)  and Gazing Behavior during  Social Interaction: An Observational  Study in Young Adults

The Oxytocin Receptor Gene (OXTR) and Gazing Behavior during Social Interaction: An Observational Study in Young Adults

... Within the belongingness literature, it is suggested that attention to meaningful social cues is a prerequisite to be able to restore a lack of inclusion (Gardner et al., 2005). As said, gazing behavior is considered to ...

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Hypomethylation of miR-142 promoter and upregulation of microRNAs that target the oxytocin receptor gene in the autism prefrontal cortex

Hypomethylation of miR-142 promoter and upregulation of microRNAs that target the oxytocin receptor gene in the autism prefrontal cortex

... targeting oxytocin receptor expression and targeting several gene ontology pathways that are relevant to autism, including synapse function and signal ...

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Genomic and epigenetic evidence for oxytocin receptor deficiency in autism

Genomic and epigenetic evidence for oxytocin receptor deficiency in autism

... parative genomic hybridization to identify 113 CNVs within 119 unrelated autistic individuals. Of note were five novel CNVs that do not map to prior regions of link- age and which, according to Fable ...

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Cyclic AMP effectors regulate myometrial oxytocin receptor expression

Cyclic AMP effectors regulate myometrial oxytocin receptor expression

... the oxytocin receptor (OTR) was one of the cAMP-repressed genes, and, given the importance of OTR in the labor process, we studied the mechanisms involved in greater detail using small interfering RNA, ...

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Effects of oxytocin receptor variants on activated signaling cascades and cellular processes

Effects of oxytocin receptor variants on activated signaling cascades and cellular processes

... - 51 - 4 Functional characterization of the oxytocin receptor variant A218T 4.1 Abstract The OTR gene variant rs4686302, a non-synonymous SNP resulting in the OTR variant A218T, has been associated with ...

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Pervasive social deficits, but normal parturition, in oxytocin receptor-deficient mice

Pervasive social deficits, but normal parturition, in oxytocin receptor-deficient mice

... Abstract The oxytocin receptor (OXTR) and its ligand, oxytocin (OXT), regulate reproductive physiology (i.e., parturition and lactation) and sociosexual behaviors. To further define the function of ...

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Oxytocin receptor and G-protein polymorphisms in patients with depression and separation anxiety

Oxytocin receptor and G-protein polymorphisms in patients with depression and separation anxiety

... The distinction made between childhood and adult separation anxiety based on the two measures used (the SASI and ASA-27) may be somewhat artificial in that it is possible that adults with heightened symptoms are prone to ...

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Sexually dimorphic effects of oxytocin receptor gene (OXTR) variants on Harm Avoidance

Sexually dimorphic effects of oxytocin receptor gene (OXTR) variants on Harm Avoidance

... the oxytocin receptor gene in Harm Avoidance and incentivize resequencing the OXTR gene in condi- tions marked by an increased sensitivity to perceived ...to oxytocin-mediated adaptive responses in ...

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Oxytocin Receptor Gene Methylation as a Molecular Marker for Severity of Depressive Symptoms in Affective Disorder Patients

Oxytocin Receptor Gene Methylation as a Molecular Marker for Severity of Depressive Symptoms in Affective Disorder Patients

... in oxytocin mRNA expression in the medial amygdala was found ...in oxytocin projections and the oxytocin receptor level in the nucleus accumbens ...

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