The poly(C) tract and pseudoknot domains
Mutational analysis of the mengovirus poly(C) tract and surrounding heteropolymeric sequences.
... Supporting this idea is the low degree of sequence conserva- tion among homologous cardioviruses. Within the singular stretch deleted in vM D 15C 13 , four substitutions and four in- sertions or deletions differentiate ...
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Mengovirus and Encephalomyocarditis Virus Poly(C) Tract Lengths Can Affect Virus Growth in Murine Cell Culture
... of poly(C) sequences is inherently dependent upon the tract length itself, and the consequent virulence or lack thereof must be a subsequent event linked to this ...
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Sufficient Length of a Poly(A) Tail for the Formation of a Potential Pseudoknot Is Required for Efficient Replication of Bamboo Mosaic Potexvirus RNA
... the pseudoknot failed to accumulate viral products efficiently, whereas the compen- satory mutants with the base-pairing restored could only am- plify up to 75% of the level of the wild ...this pseudoknot ...
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A Wild-Type Porcine Encephalomyocarditis Virus Containing a Short Poly(C) Tract Is Pathogenic to Mice, Pigs, and Cynomolgus Macaques
... FIG. 4. EMCV-induced pathological changes and detection of viral RNA in pigs. Five-week-old pigs were intraperitoneally inoculated with 2.9 ⫻ 10 8 PFU of EMCV 30, and histopathologic changes and the presence of EMCV RNA ...
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Poly(A) introduced upstream of the upstream pseudoknot domain of Tobacco mosaic virus led to sequence deletion after serial passaging in host plants
... Total RNAs were extracted from the pooled upper leaves by TRIzol® reagent. Reverse transcription was performed using the SuperScript III Reverse Transcriptase kit (Invi- trogen, USA) with primer R (5´-TGGGCCCCTACC ...
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Distribution of protein poly(ADP-ribosyl)ation systems across all domains of life
... hydrolyses poly(ADP-ribosyl)ation is poly(ADP-ribose) glyco- hydrolase ...accessory domains that precede the PARG catalytic macrodomain [44] ...of poly(ADP-ribosyl)ation as a regulatory ...
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In silico analysis of C-type lectin domains’ structure and properties
... 5.4.2 Two groups identified in higher vertebrates are not detectable in Fugu I could not detect CTLDcp representatives for groups V (NK cell receptors) and VII (lithostathine) in the Fugu genome. CTLDs in the members of ...
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Structural and Functional Basis for ADP-Ribose and Poly(ADP-Ribose) Binding by Viral Macro Domains
... phate. However, in our opinion, the available evidence does not sufficiently support a scenario in which this phosphatase activity would represent the sole biologically relevant function of the macro domain in vivo. In ...
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Titrating Gene Function in the Human Fungal Pathogen Candida albicans through Poly-Adenosine Tract Insertion
... of poly-adenosine (poly-A) tracts into an open reading frame can suppress expression of the encoded protein in both prokaryotic and eukaryotic ...the poly-A insertion, which can therefore provide a ...
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Hepatitis C Virus Internal Ribosome Entry Site-Dependent Translation in Saccharomyces cerevisiae Is Independent of Polypyrimidine Tract-Binding Protein, Poly(rC)-Binding Protein 2, and La Protein
... FIG. 5. Analysis of bicistronic RNA in yeast. A. Schematic diagram of the predicted bicistronic mRNA from plasmid ADE3-HCV C120- lacZ. The HCV IRES is shown between the open reading frames for Ade3p and  -galactosidase. ...
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Stimulation of translation by human Unr requires cold shock domains 2 and 4, and correlates with poly(A) binding protein interaction
... In vitro translation experiments using recombinant Unr protein and mutants showed that the translation stimulation activity of Unr depends on CSDs 2 and 4 within its five domain structure. This is a different pattern to ...
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Analysis of the C-Terminal Membrane Anchor Domains of Hepatitis C Virus Glycoproteins E1 and E2: toward a Topological Model
... ␣-helices extends about ⫾20 Å from the center of the mem- brane. They further emphasized that the hydrophobic residues are within ⫾10 Å from the bilayer center and that this slice is symmetrically flanked by regions rich ...
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Semantic Domains for Handel-C
... and C, designed to target hardware implementations, specifically field-programmable gate arrays ...is C-like with CSP-like parallel constructs and channel communication ...semantic domains required ...
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Inverse folding of RNA pseudoknot structures
... The core of Inv is a stochastic local search routine which is based on the fact that each 3-noncrossing RNA structure has a unique loop-decomposition, see Theo- rem 1 in Section 2.1. Inv generates “optimal” subse- ...
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Predentifier: Detecting Botnet C&C Domains From Passive DNS Data
... the C&C servers appear in public. Thus, a domain used in a C&C context is more likely to be resolved to only few IP addresses at a ...
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CHARACTERIZATION OF DOMAINS IN C n BY THEIR NONCOMPACT AUTOMORPHISM GROUPS
... ⊂ C n+1 be a bounded pseudo- convex domain of finite type whose boundary is smooth of class C ∞ , and suppose that the Levi form has rank at least n − 1 at each point of the ...
Some Descriptions of the Envelopes of Holomorphy of Domains in C n
... ∂u = f ¯ (1.5) has a C k -smooth solution u such that u is compactly supported; indeed, u ≡ 0 on the unbounded component of (supp(f )) C . Equation (1.5) is a special case of a class of partial differential ...
Ab initio study of electron transport in dry poly(G) poly(C) A DNA strands
... 12-base-pair poly共GC兲-poly共GC兲 DNA molecules on a Au共111兲 surface at room ...of poly 共 G 兲 -poly 共 C 兲 DNA molecules deposited on ...
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On Multi Poly-Genocchi Polynomials with Parameters a, b and c
... 2 Department of Mathematics, Mindanao State University, Marawi City, Philippines 3 Department of Mathematics and Statistics, College of Science and Mathematics, Mindanao State University-Iligan Institute of Technology, ...
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ExecScent: Mining for New C&C Domains in Live Networks with Adaptive Control Protocol Templates
... More specifically, consider the following hypothetical scenario. Assume we have a template τ that matches an HTTP request in both Net A and Net B with a similar- ity score s. For simplicity, let us assume the score s is ...
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