The spinal cord: Inflammation
Ganglioside deficiency causes inflammation and neurodegeneration via the activation of complement system in the spinal cord
... As shown above, even TKO mice did not achieve complete restoration of abnormal findings indicating inflammation and neurodegeneration. In particular, astro- cytosis in the nerve tissues did not decrease by the ...
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Original Article A chitosan scaffold infused with neurotrophin-3 and human umbilical cord mesenchymal stem cells suppresses inflammation and promotes functional recovery after spinal cord injury in mice
... alleviates inflammation and is a potential strat- egy to treat spinal cord injuries ...reduce inflammation, and thereby protect nerve ...
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The pathophysiological role of acute inflammation after spinal cord injury
... Traumatic spinal cord injury (SCI) causes irreparable severe motor and sensory ...blood-spinal cord barrier disruption, neural cell death, axonal damage, and demyelination, followed by a ...
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Multiple organ dysfunction and systemic inflammation after spinal cord injury: a complex relationship
... of spinal cord compres- sion, Gris et ...pulmonary inflammation is consistent with the develop- ment of lung dysfunction in the early stage of SCI ...of inflammation markers IL-6 and ...
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Targeting inflammation to influence mood following spinal cord injury: a randomized clinical trial
... The present study demonstrated that it was possible to improve mood in individuals with SCI by means of redu- cing inflammation. Such improvements may relate to positive changes in neuroactive compounds of the ...
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FEV1 and FVC and systemic inflammation in a spinal cord injury cohort
... SCI level and severity was assessed by exam and medical record review. Motor level and completeness of injury was categorized according to the American Spinal Injury Association Impairment Scale (AIS) [37]. ...
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Original Article Neuroprotective effects of diosgenin in rats with experimental spinal cord injury via promotion of autophagy
... of inflammation and reduces inflammatory response through various ...skin inflammation could be repressed by DSG treatment through attenuation of IL-4 and IL-6 expression ...
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Marked central nervous system pathology in CD59 knockout rats following passive transfer of Neuromyelitis optica immunoglobulin G
... astrocytopathy, inflammation, deposition of activated complement, and demyelination, whereas identically treated CD59 +/+ rats showed minimal ...with inflammation and deposition of activated complement in ...
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Transgenic Expression of the 3D Polymerase Inhibits Theiler's Virus Infection and Demyelination
... and Spinal Cord corresponding to sections 220 and 350, page 6 ...minimal inflammation; 2, early tissue destruction (loss of architecture) and moderate inflammation; 3, definite tissue ...
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Neuromodulation in the treatment of symptoms of spinal cord injury
... Spinal cord injury (SCI) is one of the most common causes of death and disability in the world ...health. Spinal cord injury results from mechanical trauma to neurons, glial cells and adjacent ...
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Theiler’s Virus Infection of Perforin-Deficient Mice
... the spinal cord, mainly in macrophages, but also in astrocytes and oligodendrocytes (1, 25, 30, ...parenchymal inflammation, and myelin destruction with conservation of axons (7, ...
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8-12-2011 12:00 AM In Vivo Cellular MRI In Experimental Traumatic Spinal Cord Injury
... Spinal cord injury (SCI) remains one of the most devastating conditions in medicine; not only are lives lost but also there is a loss of productive life years and a high economic burden placed on our ...
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Targeting prokineticin system counteracts hypersensitivity, neuroinflammation, and tissue damage in a mouse model of bortezomib-induced peripheral neuropathy
... and spinal cord correlates with the presence of neuro- inflammation and the development of experimental neuropathic pain induced in mice by damage to the sciatic nerve [14, 20, 21] or by a metabolic ...
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The therapeutic effect of anti-CD52 treatment in murine experimental autoimmune encephalomyelitis is associated with altered IL-33 and ST2 expression levels
... (CNS) inflammation were reduced following the treatment, which was accompanied by peripheral T and B lymphocyte depletion and reduced production of various cytokines including IL-33, while sST2 was ...In ...
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Mystery Case: A 61-year-old woman with lower extremity paralysis and sensory loss
... extensive spinal cord lesion on MRI and nonspecific evidence of inflammation in CSF with an otherwise negative infectious, metabolic, and systemic inflammatory ...
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PubMedCentral-PMC5014366.pdf
... exposed spinal cord that can be accidentally lesioned during the surgical ...the spinal cord, thus minimizing the incidence of paralysis during ...cervical spinal cord and ...
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Effect of N-acetylcysteine and allopurinol combination to protect spinal cord ischemia/reperfusion injury induced by aortic cross-clamping in rat model
... Lipid peroxidation has been reported as an important contributor to the loss of cell function under oxidative stress conditions. The end production of lipid peroxida- tion includes aldehydes, hydrocarbon gases, and MDA ...
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Cystic Necrosis of the Spinal Cord in Compressive Cervical Myelopathy: Demonstration by lopamidol CT Myelography
... Certainly a patient with mid-cervical spondylosis and secondary necrosis and/or cavitation syrinx extending up into the upper cervical spinal cord and down into the thoracic spinal cord [r] ...
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Neurological outcome of treatment for patients with impending paralysis due to epidural spinal cord compression by metastatic spinal tumor
... (n = 55) (Table 1). In the posterior decompression and stabilization group, spinal cord decompression at the com- pressed level and posterior stabilization of 2–3 vertebras with pedicle screws were ...
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1H MR Spectroscopy in the Human Spinal Cord
... with spinal cord ...the spinal cord include investigation of neuroregeneration and reor- ganization following spinal cord injury and monitoring during rehabilitation or ...
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