the thymus
T cell selection in the thymus
... Chapter 3 describes mice carrying a temperature sensitive SV40 large T antigen under the control of class I H-2K^ promoter (H2ts m i c e ) . These mice develop normally except for the enlargement of the thymus in ...
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Quantitative dissection of T cell negative selection mechanisms in the thymus
... Different mechanisms of cell death may operate in MHCI-responsive versus MHCII- responsive thymocytes. This hypothesis is based on the facts that although both cohorts have similar fractions of apoptosis-committed cells, ...
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The Thymus: A Forgotten, But Very Important Organ
... the thymus was not thought to play any role in the regulation of the immune ...“the thymus is not in- volved in the regulation of immune responses” ...the thymus or to its cells” [5]. Immunologists ...
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Viral infection of the thymus.
... Our results show that i infection starts at the fetal stage and is maintained throughout adulthood, and ii this chronic infection of the thymus can be eliminated by transfer of virus-spe[r] ...
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Successful Transplantation of the Thymus in Nezelof's Syndrome
... A 6-month-old girl with congenital thymic dysplasia or Nezelof’s syndrome (lack of I cell function and normal levels of immunoglobulins) was given a transplant of a human thymus gland fr[r] ...
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Seasonal Cyclical Changes in the Thymus of the Mallard
... Thymus section of adult male mallard killed 16 July 1945 x 7 during period of thymic enlargement.. Cortical and medullary zones well demarcated; lobulation well developed.[r] ...
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THE THYMUS AND OTHER LYMPHOID TISSUES IN CONGENITAL AGAMMAGLOBULINEMIA
... Plasma cells and germinal follicles are absent from the tissues of both groups of patients, but the marked generalized pau- city of small lymphocytes in these patients with thymic alymph[r] ...
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THE THYMUS AND OTHER LYMPHOID TISSUES IN CONGENITAL AGAMMAGLOBULINEMIA
... the extract given 22 days after transplanta- tion of skin and thymus resulted in an area of erythema 1.5 cm in diameter with a central purplish area of induration approxi-.. mately 0.6 c[r] ...
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In-vitro assessment of antioxidant and antimicrobial activities of methanol extracts and essential oil of Thymus hirtus sp. algeriensis
... The sesquiterpenes were also represented mainly by oxygenated sesquiterpenes (8.32% and 35.54%) in con- trast to what has been observed by Ben El Hadj Ali [28], where the amount of oxygenated sesquiterpenes did not ...
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VIP Regulates the Development & Proliferation of Treg in vivo in spleen
... the thymus and spleen, and support the concept that exo- genous VIP is able to induce ...in thymus – to determine if there are long-term effects on Treg with VIP treatment; 2) In vitro stimulation of Tregs ...
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Mitochondrial uncoupling protein 1 expression in thymocytes
... In this study we have con fi rmed the expression of UCP 1 in mouse and rat thymocyte, as determined by the Thy-1 marker surface antigen and their size (~5 μ m in diameter), mitochondria by confocal imagery. Nevertheless, ...
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CT density of cervical thymus, in comparison with mediastinal thymus
... ultrasound, thymus of infants may be homoge- neous, with echogenicity slightly less than liver and spleen [6] or have multiple linear or branching echo- genic foci ...(mediastinal) thymus [4], and the same ...
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Aag DNA Glycosylase Promotes Alkylation-Induced Tissue Damage Mediated by Parp1
... the thymus, spleen, bone marrow, retina, pancreas, and ...highly-proliferative thymus, spleen, and bone marrow, unrepaired BER intermediates presumably result in replication fork collapse and DSBs, thus ...
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Papillary carcinoma thyroid with metastasis to ectopic cervical thymus
... neck since 1 year. The only complaint was that of disfig- urement. There was no other significant history. On examination, a single swelling was present in anterior neck, 13 × 8 cm in size, irregular in shape, extending ...
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Understanding T Cell Recovery Following Thymus Injury
... the thymus, revealing that there are approximately 12 thymic settling progenitors in 10 million intravenously injected bone marrow progenitors that settle within a single ...the thymus can be compensated ...
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Purinergic signalling in endocrine organs: Testis, thyroid, thymus
... Y (Falzoni et al. 1995). Stimulation o f P2X? receptors on macrophages and microglia was reported to cause interleukin 1|3 (IL -ip ) release, which is an important inflammatory messenger (Ferrari et al. 1997a). P 2 X 7 ...
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Determination of shelf life of Chelidonium majus, Sambucus nigra, Thymus vulgaris and Thymus serpyllum herbal tinctures by various stability indicating tests
... Thymol (Figure 1) and other volatile components of the Thymus sp. are usually analysed by gas chromatography (GC) (De Lisi et al., 2011; Móricz et al., 2012; Sgorbini et al., 2015; Staszek et al., 2014; Thompson ...
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VEGF System in Dog’s Thymus—Temporal Expression
... Data presented as standard deviation and standard error of the mean, were submitted to the Kolmogorov-Smir- nov normality test and when not normally distributed, transformed into logarithms. Statistical analysis of the ...
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Mechanisms of thymus organogenesis and morphogenesis
... the thymus have been sources of controversy within the ...of thymus organogenesis (Auerbach, 1960), embryonic thymus lobes from mice were dissociated into the epithelial primordium and the ...
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Transplantation of thymic autoimmune microenvironment to severe combined immunodeficiency mice A new model of myasthenia gravis
... dissociated thymus cells only lead to a transient increase of anti-acetylcholine receptor ...gravis thymus is able to induce and maintain autoantibody production in immunodeprived host animals, and that ...
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