The Type III virulence export system
The Structure of an Injectisome Export Gate Demonstrates Conservation of Architecture in the Core Export Gate between Flagellar and Virulence Type III Secretion Systems
... ABSTRACT Export of proteins through type III secretion systems (T3SS) is critical for motility and virulence of many major bacterial ...defined export gate complex consisting of three ...
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T3SEdb: Data warehousing of virulence effectors secreted by the bacterial Type III Secretion System
... host type (plant versus animal), quality of experimental methods used to identify the effectors and BLAST search score of known effectors against bacterial genomes, among ...
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Integrated regulation of the type III secretion system and other virulence determinants in Ralstonia solanacearum
... the Type III secretion system (TTSS) that directly translocates effector proteins into the eukaryotic host cells is essential for the development of ...other virulence determinants and genes ...
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Identification of a Type III Thioesterase Reveals the Function of an Operon Crucial for Mtb Virulence
... ‘‘specialized’’ acyl carrier protein encoded by Rv0100 to produce acyl-ACP, a precursor for the NRPS to generate a lipopeptide. Unlike the mycobactin NRPS, it is believed, based on the sequence analysis, that the gene ...
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In Vitro Reconstitution of Functional Type III Protein Export and Insights into Flagellar Assembly
... assay system with easy control of measurement conditions is needed for further in-depth mechanistic understanding of protein ...assay system that enables accurate measurements of protein trans- port under ...
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Density profile of group B streptococci, type III, and its possible relation to enhanced virulence
... The buoyant densities of virulent and colonizing group B streptococci, type III, were determined by centrifugation of bacteria on a linear, hypotonic density gradient.. A total of 28 str[r] ...
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High incidence of type III secretion system associated virulence factors (exoenzymes) in Pseudomonas aeruginosa isolated from Iranian burn patients
... of virulence factors and antimicrobial resistance profile of Pseudomonas aeruginosa strains isolated from Iranian burn ...of virulence genes was determined by PCR ...of type III secretion ...
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Quantification of the physiochemical constraints on the export of spider silk proteins by Salmonella type III secretion
... The spider silk family of proteins encompasses a wide range of amino acid compositions and physiochemical properties, which ultimately result in diverse mechanical properties. Using sequence information from Genbank, the ...
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THE ROLE OF SECA2 PROTEIN EXPORT IN THE VIRULENCE OF MYCOBACTERIUM TUBERCULOSIS
... protein export, we utilized genome-wide genetic interaction mapping to further elucidate the functions and mechanisms of the SecA2 export pathway of ...
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Regulation of type III secretion system in Pseudomonas syringae
... known regulators. KB/pin/min/fin genes may regulate the known TTSS gene regulatory genes at posttranslational level, and this can be determined by examining the known regulatory proteins in the KB/pin/min/fin mutants by ...
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The Type III Secretion System of Pathogenic Escherichia coli
... and Export Apparatus There are four major components of the injectisome: the needle, the basal body, the export apparatus and the cytoplasmic protein ...the export apparatus (Diepold et ...membrane ...
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The role of type III effectors from Xanthomonas axonopodis pv. manihotis in virulence and suppression of plant immunity
... AvrBs2 has been shown to be important in bacterial viru- lence and PTI suppression in Xam. However, avrBs2 is not con- sidered to be a core T3E gene in Xam (Bart et al., 2012) because of a premature stop codon in one ...
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The role of the Mycobacterium tuberculosis SecA2 protein export pathway in virulence
... protein export system is important for blocking phagosome ...our system, would be required to define phagosome- lysosome fusion of ΔsecA2 mutant containing ...
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Virulence determinants of Pseudomonas syringae strains isolated from grasses in the context of a small type III effector repertoire
... This, however, does not completely exclude the possibility that the strain possesses other, so far unknown, effectors, but if indeed present, their contribution to the overall virulence appears negligible. This ...
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Virulence determinants of Pseudomonas syringae strains isolated from grasses in the context of a small type III effector repertoire
... of type III-secreted effectors and other virulence factors, including small secreted molecules such as syringolin A, a peptide derivative that inhibits the eukaryotic ...analyze virulence ...
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Diverse Evolutionary Mechanisms Shape the Type III Effector Virulence Factor Repertoire in the Plant Pathogen Pseudomonas syringae
... these type III effector genes led to 11 were detected in the genome of ...one type III ef- are present in the genome but not in the unfinished fector family might be used by different ...
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Current knowledge on the Ralstonia solanacearum type III secretion system
... Despite all our current knowledge on R. solanacearum T3E derived from the combination of genomic, biochemi- cal and pathology data obtained in the last two decades, there is still a considerable number of effectors with ...
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Control of cyclic oligoadenylate synthesis in a type III CRISPR system
... CRISPR system for prokaryotic adaptive immunity provides RNA-mediated protection from viruses and mobile genetic ...detected, type III systems adopt an activated state that licenses DNA interference ...
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Clinical impact of the type VI secretion system on virulence of Campylobacter species during infection
... factors, virulence of the pathogen and initiated therapy. The type VI secretion system (T6SS) has been identified as a novel virulence factor, which mediates contact-dependent injection of ...
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An indirect enzyme-linked immunosorbent assay for rapid and quantitative assessment of Type III virulence phenotypes of Pseudomonas aeruginosa isolates
... patients. Virulence fac- tors other than T3SS proteins may also contribute to clin- ical virulence of ...as Type IV pili and flag- ella, has been correlated with changes in virulence in ani- ...
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