The Zebrafish Retina
Identification of novel circadian transcripts in the zebrafish retina
... made zebrafish a model organism of choice for developmental biology and ...the zebrafish genome that are expressed in the zebrafish ...the zebrafish retinal ...
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Age-related degeneration leads to gliosis but not regeneration in the zebrafish retina
... the zebrafish retina. (A) Central retina thinning in both WT and tert -/- , at young (5 months) and old ages (>30 months in WT and 20 months in tert -/- ...central retina thickness, (A’) in ...
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A moving wave patterns the cone photoreceptor mosaic array in the zebrafish retina
... inner retina and discusses limitations of mathematical simulations that reproduce the zebrafish cone mosaic ...developing zebrafish cone mosaic, and a model is proposed that invokes spatiotemporally ...
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Inflammation and Matrix Metalloproteinase 9 (Mmp-9) Function in the Zebrafish Retina
... In chapter 2, I present data demonstrating that inflammation and matrix metalloproteinase 9 (mmp-9) function to regulate photoreceptor regeneration. First, I characterized the expression of genes encoding inflammatory ...
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Staggered cell intrinsic timing of ath5 expression underlies the wave of ganglion cell neurogenesis in the zebrafish retina
... the retina, neurogenesis spreads through the field of progenitors following a precise spatiotemporal pattern, the essential features of which are conserved across vertebrates (reviewed by Vetter and Brown, ...
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Sonic hedgehog, secreted by amacrine cells, acts as a short range signal to direct differentiation and lamination in the zebrafish retina
... the retina may be either due to the fact that Shh, secreted by amacrine cells, affects precursor cells, which span the whole epithelium, or that the direct or indirect range of Shh is greater in this ...the ...
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Vsx2 in the zebrafish retina: restricted lineages through derepression
... Imaging of fixed samples Whole or partial embryo images were acquired on a dis- secting stereo microscope equipped with epi-fluorescence (Leica MZ FLIII). Photomicrography of whole-mount eyes or sections was performed ...
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penner/lgl2 is required for the integrity of the photoreceptor layer in the zebrafish retina
... As shown here, loss of zygotic pen/lgl2 activity does not induce any gross modifications of apico-basal polarity and compartment size in PRCs of the larval retina. The inner and OSs develop normally and are ...
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Dynamic changes in microglial and macrophage characteristics during degeneration and regeneration of the zebrafish retina
... continued accumulation of immune cells through 72 hpi (Fig. 5A, B). These cell cycle markers indicate that infil- trating immune cells prepare for division upon their ar- rival to damaged retinal tissue, and resident ...
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Id2a influences neuron and glia formation in the zebrafish retina by modulating retinoblast cell cycle kinetics
... and zebrafish (Chong et al., 2005; Thisse et al., 2004) retina, and Id2 –/– mice are microphthalmic (Yokota et ...developing retina to facilitate proliferation, cell fate specification and neuronal ...
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In vivo electroporation of morpholinos into the adult zebrafish retina.
... pup retina 21 ...adult zebrafish retina with survival of 100% of the treated ...mouse retina in vivo and the zebrafish retina in explants suggests it is still a possibility in ...
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A possible role of neuroglobin in the retina after optic nerve injury: A comparative study of zebrafish and mouse retina
... upregulation of Ngb in the fish retina and downregulation of Ngb in the mouse retina. On the basis of these results, we tried to achieve overexpression of mouse Ngb in RGC-5 cells, a retinal precursor cell ...
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Meis1 specifies positional information in the retina and tectum to organize the zebrafish visual system
... Smads1 and 5 have been shown to act redundantly in some processes, such as bone formation and tumour suppression [61-63], yet perform distinct functions dur- ing embryonic DV patterning and blood development [82,83]. The ...
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Ptf1a is expressed transiently in all types of amacrine cells in the embryonic zebrafish retina
... the zebrafish retina, suggesting that this aspect of fate deter- mination might occur in a critical temporal window dur- ing the early development of individual neurons that then differentiate into ...
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Targeting of amacrine cell neurites to appropriate synaptic laminae in the developing zebrafish retina
... the zebrafish retina clearly demonstrate that once the processes of amacrine cells reach the forming synaptic neuropil of the IPL, their arbors lateralize preferentially within the appropriate ...
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Anisotropic Müller glial scaffolding supports a multiplex lattice mosaic of photoreceptors in zebrafish retina
... fish retina is a compelling example of a highly ordered epithelial cell pattern, with single cell width rows and columns of cones and precisely defined neighbor relationships among different cone ...the ...
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β-catenin/Wnt signaling controls progenitor fate in the developing and regenerating zebrafish retina
... adult zebrafish retina [19]. Since the zebrafish retina has both an active popula- tion of stem cells in the CMZ, and a robust regenerative proliferation of the Müller glial cells, it is an ...
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Capn5 Expression in the Healthy and Regenerating Zebrafish Retina
... calpain, zebrafish, regeneration, photoreceptors, development C alpains are a family of calcium-dependent, nonlysosomal cysteine proteases that include at least 15 family members in ...
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The MicroRNA, miR‐18a, Regulates NeuroD and Photoreceptor Differentiation in the Retina of Zebrafish
... of zebrafish embryos at 30, 48, and 70 hpf with a miRVana miRNA isolation kit and then, on the same samples, standard qPCR was performed for pre-miR-18a and TaqMan qPCR for mature ...and retina tissues, ...
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β-catenin/Wnt signaling controls progenitor fate in the developing and regenerating zebrafish retina
... larval zebrafish for 2 days in the GSK3β inhibi- tor 1-azakenpaullone (from 6 to 8 dpf ) is not sufficient to trigger dedifferentiation and proliferation of Müller glia, in contrast to what was reported for ...
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