Therapeutic efficiency.
In vivo Biocompatibility, Biodistribution and Therapeutic Efficiency of Titania Coated Upconversion Nanoparticles for Photodynamic Therapy of Solid Oral Cancers
... PDT efficiency were studied in ...the therapeutic effect of these nanoparticles following systemic administration in vivo, its biodistribution and long term (120 d) toxicity profiles were analyzed, to ...
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Modulatory Effect of Lovastatin on Therapeutic Efficiency of Conventional Antidiabetics on Pancreatic and Cardiovascular Complications of Diabetes
... Modulatory Effect of Lovastatin on Therapeutic Efficiency of Conventional Antidiabetics on Pancreatic and Cardiovascular Complications of Diabetes.. Ehab A.M.[r] ...
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Therapeutic Efficiency of spirulina against Lead Acetate Toxicity on the Fresh Water Fish Labeo rohita
... Abstract: The release of heavy metals in to the aquatic environment causes water pollution problems because of their toxicity, persistence and bioaccumulation. Lead has no known role to play in the human body that is ...
6
Probucol enhances the therapeutic efficiency of mesenchymal stem cells in the treatment of erectile dysfunction in diabetic rats by prolonging their survival time via Nrf2 pathway
... Background: Intracavernous injection of mesenchymal stem cells (MSCs) is a promising method for diabetic mellitus-induced erectile dysfunction (DMED), but short survival time of MSCs in cavernous is a fatal defect for ...
11
Apparent diffusion coefficient as an effective index for the therapeutic efficiency of brain chemoradiotherapy for brain metastases from lung cancer
... Tumors with higher ADC values often contain more necrotic tissue and/or damaged cell mem- branes, with a poorer blood perfusion, and are rela- tively insensitive to radiotherapy [38], indicating that pre-radiotherapy ADC ...
7
Therapeutic efficiency of folated poly(ethylene glycol)-chitosan-graft-polyethylenimine-<em>Pdcd4</em> complexes in H-<em>ras</em>12V mice with liver cancer
... FPCP transfection efficiency was determined by intra- venous injection of 30 µ g of GFP plasmid in 200 µ L. The animals were sacrificed 48 hours after injection, and their livers were isolated and fixed in ...
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<p>Improved ADM Penetration Distance and Therapeutic Efficiency in a Rabbit VX2 Liver Cancer Model by Relaxin Infusion Combined with Transcatheter Chemoembolization Through Hepatic Artery</p>
... the therapeutic effects were then studied by transcatheter pro- cedures, which have not been performed before as far as we know, but just Golubnitschaja et al reported that TACE treated patients tending to better ...
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Comparative analysis of therapeutic efficiency and costs (experience in Bulgaria) of oral antidiabetic therapies based on glitazones and gliptins
... the efficiency of pioglitazone is associ- ated with the implementation of good glycemic control and improvement of insulin sensitivity on the one hand; on the other hand it improves dyslipidemia, hypertension and ...
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Evaluating the therapeutic efficiency and drug targeting ability of alkaloids present in Rauwolfia serpentina
... R. serpentina is well documented to exhibit potential medical values for treatment of hypertensive and neurological disorders. Extensive research has been carried out exploring its antihypertensive properties; however, ...
11
PREPARATION AND EVALUATION OF ISONIAZIDE NANO CONJUGATES FOR IMPROVING THE THERAPEUTIC EFFICIENCY
... proven efficiency in improving the therapeutic efficacy of many ...the efficiency of the plant extract to conjugate the drug. The therapeutic efficacy of the conjugated drug was evaluated ...
7
Thermo- and pH-dual responsive polymeric micelles with upper critical solution temperature behavior for photoacoustic imaging-guided synergistic chemo-photothermal therapy against subcutaneous and metastatic breast tumors
... Herein, an amphiphilic polymer, poly(ethylene glycol)-b-poly(acrylamide-co-acrylonitrile-co-vinylimi dazole) copolymer (mPEG-PAAV), was synthesized, the UCST of which is automatically changed at different pH values. In ...
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Pharmacological inhibition of Bmi1 by PTC-209 impaired tumor growth in head neck squamous cell carcinoma
... the therapeutic efficiency of PTC-209, a novel and selective inhibitor of Bmi1, against HNSCC using both in vitro cell culture and in vivo xenograft animal ...
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DESIGN, DEVELOPMENT AND OPTIMIZATION OF LETROZOLE NANOPARTICLES FOR BREAST CANCER TREATMENT
... the therapeutic efficiency, to decrease toxicity as well as to minimize the drug side ...entrapment efficiency (EE) of nanoparticles (NPs) were evaluated by UV-Vis ...
7
<p>Multifunctional hypoxia imaging nanoparticles: multifunctional tumor imaging and related guided tumor therapy</p>
... Precise tumor therapy requires technological progress in tumor imaging and therapy. Hypoxia is a key factor involved in the whole tumor genesis, growth, metastasis, and inva- siveness processes. Investigating hypoxia ...
13
Suppression of MicroRNA let 7a Expression by Agmatine Regulates Neural Stem Cell Differentiation
... self-renewal and proliferation are important characteristics for the enhanced therapeutic efficiency of NSCs in the brain.7 Agmatine is an endogenous amine produced by decarboxylation of[r] ...
7
The use of therapeutic story in primary school settings in China
... psychological counsellors in using this therapeutic technique. Overall, the findings of this study may help to inform the future implementation of therapeutic storytelling in primary school settings in ...
8
Chemotherapy for second-stage Human African trypanosomiasis (Review)
... Melarsoprol, a trivalent organic arsenical compound, has been the drug of choice for second-stage HAT caused by either T. b. gam- biense or T. b. rhodesiense since 1949. Melarsoprol is liposoluble and for this reason can ...
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High efficiency gene transfer into nontransformed cells: utility for studying gene regulation and analysis of potential therapeutic targets
... The elucidation of the signalling pathways involved in inflammatory diseases, such as rheumatoid arthritis, could provide long sought after targets for therapeutic intervention. Gene regulation is complex and ...
11
Therapeutic effects of maximal strength training on walking efficiency in patients with schizophrenia – a pilot study
... A controlled pilot study with pre-post intervention design was carried out. One group performed MST and one group spent the same amount of time playing computer games (CG). A non-randomized trial design was incorpo- ...
7
Erratum to: New developments in anti malarial target candidate and product profiles
... Therapeutic ratio >tenfold between therapeutic exposure and NOAEL no adverse Therapeutic ratio >50-fold between therapeutic effects level in preclinical studies, and easily ‘monitorable’[r] ...
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