Therapeutic Strategies
Therapeutic strategies in pneumonia: going beyond antibiotics
... promising therapeutic targets have been identified and numerous innovative therapeutic approaches demonstrated to improve lung injury in experimental preclinical ...curative strategies for the ...
9
Angiogenesis and vasculogenesis as therapeutic strategies for postnatal neovascularization
... for therapeutic neovascularization, because ECs represent the critical cellular element responsible for new vessel formation ...for therapeutic strategies to recapitulate and/or optimize native ...
7
Metabolic reprogramming: the emerging concept and associated therapeutic strategies
... Aberrant proliferation of cancer cells is supported by en- hanced adaptation to nutrient microenvironment mediated by alterations in energy metabolism. Consequently, meta- bolic reprogramming is believed to be one of the ...
10
Refractory chronic lymphocytic leukemia – new therapeutic strategies
... biologically-targeted therapeutic strategies against relapsed and refractory CLL include antibody- based therapies as well as small ...new therapeutic strategies are needed and have to prove ...
11
Therapeutic strategies in epithelial ovarian cancer
... 18.8%) Therapeutic Strategies in Epithelial Ovarian Cancer and this is important informa- tion since hypersensitive reactions are reported in the general practice in patients treated with carboplatin up to ...
8
Therapeutic strategies for spinal muscular atrophy: SMN and beyond
... survival. Therapeutic strategies to increase SMN are in clinical trials, and the first SMN2-directed antisense oligonucleotide (ASO) therapy has recently been ...complementary strategies may be ...
12
A review of bronchiolitis obliterans syndrome and therapeutic strategies
... A small number of studies have assessed the different therapeutic modalities that are reportedly beneficial in these patients. Adjustments in immunosuppressant ther- apy and the use of immunomodulating medications ...
9
Therapeutic Strategies of Stem Cell Transplantation for Liver Cirrhosis
... Cirrhosis is a common consequence of chronic liver diseases, which leads to the liver failure during the decompensation stage. Liver transplantation is the only therapeutic option for advanced cirrhosis. However, ...
19
Novel molecular insights and new therapeutic strategies in osteosarcoma
... Based on the data available on clinicalTrials.gov, many inhibitors including multitarget inhibitors, IGF1-R inhib- itors, mTOR inhibitors and inhibitor of Wnt/β-catenin signaling have been applied to clinical trials ...
23
Current therapeutic strategies for invasive and metastatic bladder cancer
... for invasive and metastatic bladder cancers, and various prognostic and predictive factors to determine therapeutic outcomes and potential for treatment-related toxicities. We performed a systematic review of ...
17
Transcription factors: Are they a real target for future therapeutic strategies?
... anovel therapeutic approach using transcription factors as medication comes with the cell type specific delivery system, a well known and not yet solved problem with the existing ...
22
The arsenal of pathogens and antivirulence therapeutic strategies for disarming them
... Abstract: Pathogens deploy an arsenal of virulence factors (VFs) to establish themselves within their infectious niche. The discovery of antimicrobial compounds and their development into therapeutics has made a ...
12
Bronchopulmonary dysplasia: clinical aspects and preventive and therapeutic strategies
... condition was diagnosed mainly in MPT and was con- sidered the consequence of an inadequate therapeutic approach to neonatal respiratory distress syndrome (RDS) [6]. RDS is a respiratory disorder chiefly of ...
13
ROLE OF THERAPEUTIC STRATEGIES IN THE FIELD OF CANCER STEM CELLS
... additional capability to modify their surfaces with targeting agents such as mAbs and peptides. High target selectivity and internalization can be achieved by surface modification of nanoparticles with targeting ...
9
Advances in developing novel therapeutic strategies for Alzheimer’s disease
... Different strategies are developed at modulating im- mune cell function in neuroinflammation such as redu- cing gene expression of cytokines, inhibiting cytokine release and preventing cytokines binding to their ...
20
Hemangiomas current therapeutic strategies
... multiple therapeutic options available for patients with problematic or life threatening hemangiomas, some of which have serious side ...rapeutic strategies that are based on the inhibition of ...
8
THERAPEUTIC STRATEGIES FOR THE TREATMENT OF PERIODONTITIS
... Periodontal disease is a localised inflammatory response caused by the infection of a periodontal pocket arising from the accumulation of subgingival plaque. Periodontal disease has been considered as a possible risk ...
6
A walk through tau therapeutic strategies
... Several therapeutic approaches have been proposed, including the inhibition of protein kinases or protein-3-O-(N-acetyl-beta-D-glucosaminyl)-L-serine/threonine Nacetylglucosaminyl hydrolase, the inhibition of tau ...
31
EMERGING THERAPEUTIC STRATEGIES OF NEUROPATHIC PAIN
... Abnormal action potential can be generated from enhanced expressions by ion channels, receptors and/or neurons and such synaptic transmission can result in neuropathic pain. Now days, many pharmaceutical industries are ...
11
Current Therapeutic Strategies and Novel Approaches in Osteosarcoma
... attractive therapeutic target for the treatment of tumors including osteosarcoma ...potential therapeutic value of mTOR inhibitors in osteosarcoma ...
26