Therapeutic Vaccines
Therapeutic vaccines in non-small cell lung cancer
... of vaccines that appear able to elicit an effective immune response against tumor ...cancer vaccines have never been a popular ...These vaccines have demon- strated low toxicity together with ...
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Therapeutic vaccines and cancer: focus on DPX-0907
... cancer vaccines, we developed a novel non-emulsion depot-forming vaccine platform called DepoVax™ ...a therapeutic cancer vaccine, ...DPX-based therapeutic cancer vaccine(s), with a focus on ...
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<p>Cervical Cancer: Emerging Immune Landscape and Treatment</p>
... prophylactic vaccines against ...involving therapeutic vaccines are ...a therapeutic HPV16 E6/7 vaccines pro- vided a highly effective immune response in murine models, evoking CD8+ and ...
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Parenteral–Oral Immunization with Plant-Derived HBcAg as a Potential Therapeutic Vaccine against Chronic Hepatitis B
... new therapeutic routes are extensively investigated and are also in clinical trials ...including therapeutic vaccines ...potential therapeutic vaccine against CHB ...
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Review Article Prophylactic and Therapeutic Human Papillomavirus Vaccine: A breakthrough for women health
... new vaccines, more interest is being shown in the use of vaccines to reduce the economic burden of diseases on a country's health ...and therapeutic vaccines, because of the high economical ...
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A quantitative analysis of therapeutic cancer vaccines in phase 2 or phase 3 trial
... peutic vaccines encompassing various ...of therapeutic vaccines, including Phase 3 ...for therapeutic vac- cines, an appreciation of the minimal toxicity associated with immunotherapy compared ...
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Prophylactic and therapeutic DNA vaccines against Chagas disease
... of therapeutic vaccines may help to reduce the risk of developing the acute stage of infection and therefore the associated pathology, but the parasite cannot be totally ...
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Chimeric HBcAg virus-like particles presenting a HPV 16 E7 epitope significantly suppressed tumor progression through preventive or therapeutic immunization in a TC-1-grafted mouse model
... HBcAg-E7 49–57 VLP immunization prevented TC-1 tumor growth in both preventive and treatment studies, indicating that VLPs effectively elicit specific antitumor cellular immune responses. To further demonstrate the ...
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Therapeutic cancer vaccines
... Cancer vaccines have been vilified because they do not approach the effectiveness of adoptive T cell transfer ...most therapeutic vaccines against nonviral ...Personalized vaccines against ...
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Recombinant Viruses for Cancer Therapy
... Antitumor therapeutic vaccines, which are based on viruses encoding tumor-specific antigens, boost anti-cancer immune responses by enhanced presentation of the tumor antigens to immune ...cell-based ...
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DNA Vaccines: Regulatory Considerations and Safety Aspects
... DNA vaccines have great potential as preventive or therapeutic vaccines against viral, bacterial, or parasitic diseases as well as cancer, and may also be used as gene therapy ...DNA vaccines ...
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SARS-CoV-2/COVID-19: Viral Genomics, Epidemiology, Vaccines, and Therapeutic Interventions
... SARS-CoV-2 is a β-coronavirus similar to the viruses that cause SARS (severe acute respiratory syndrome) and MERS (Middle East respiratory syndrome). Human coronaviruses are not new and have been identified in the ...
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Endoplasmic reticulum stress enhances the antigen-specific T cell immune responses and therapeutic antitumor effects generated by therapeutic HPV vaccines
... strong therapeutic effect in several cancer treatments, while other immunotherapies are gradually re- ceiving more attention in cancer therapy [2, 13, ...DNA vaccines emerge as a practical and attractive ...
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Therapeutic Efficacy of Vectored PGT121 Gene Delivery in HIV-1-Infected Humanized Mice
... the therapeutic monoclonal antibody (MAb) in ...shown therapeutic efficacy against infectious diseases, including Yersinia pestis (12), respiratory syncytial virus (13), and West Nile virus (14), as well as ...
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Antitumor effect of therapeutic HPV DNA vaccines with chitosan-based nanodelivery systems
... DNA vaccines have emerged as a potentially promising approach for the control of tu- ...DNA vaccines, if the delivery system can be directed to APC and induce DNA vaccine release in endolysosomes, an ...
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Multiple therapeutic peptide vaccines consisting of combined novel cancer testis antigens and anti angiogenic peptides for patients with non small cell lung cancer
... Lung cancer is the leading cause of cancer death in the world [1]. Despite the recent development of novel treat- ment modalities for patients with non-small cell lung cancer (NSCLC), survival rates are still ...
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Evaluation of the Safety and Protection E cacy of spiC and nmpC or rfaL Deletion Mutants of Salmonella Enteritidis as Live Vaccine Candidates for Poultry Non-Typhoidal Salmonellosis
... To eradicate intracellular Salmonella, it is critical to stimulate cellular immune responses in the immunized animals [39,40]. At the acute infection stage, the Salmonella-infected host can produce both Th1 and Th2 ...
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E ect of Di erent Adjuvants on the Longevity and Strength of Humoral and Cellular Immune Responses to the HCV Envelope Glycoproteins
... these vaccines could induce both cytotoxic and humoral immune responses targeting HCV despite the lack of a detectable E1/E2-specific CD8 responses in our ...
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Considering Genomic and Immunological Correlates of Protection for a Dengue Intervention
... across serotypes without variants [106,127,137] could achieve this goal (Figure 3). Key benefits of this approach include the avoidance of antibody responses which may enhance infection or have autoreactivity to host. It ...
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Assessing Vaccine Hesitancy among Healthcare Workers: A Cross-Sectional Study at an Italian Paediatric Hospital and the Development of a Healthcare Worker’s Vaccination Compliance Index
... This survey shows that vaccine hesitancy issues exist and are relevant in the investigated hospital, with substantial differences between departments and professional classes. The departments most affected by this ...
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