Thermal Hyperalgesia
Evidence for Positive Effects of Date Extract That Attenuates Thermal Hyperalgesia in a Diabetic Rat Model of Neuropathic Pain
... study hyperalgesia response and to compare the effect of date extract and melatonin in preventing pain, hot plate and tail flick tests were ...by thermal pain response and explorative activity ...to ...
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The Effect of a Combination of Swim Training and Magnesium Supplementation on Thermal Hyperalgesia in Diabetic Rats
... the thermal hyperalgesia in diabetic rats ...ameliorated thermal hypersensitivity in spinal nerve–ligated rats, a neuropathic pain model ...the thermal hyperalgesia (18) ...of ...
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Enhancement of antinociception by coadminstration of minocycline and a non steroidal anti inflammatory drug indomethacin in naïve mice and murine models of LPS induced thermal hyperalgesia and monoarthritis
... In this study the antinociceptive effects of co-adminis- tration of minocycline with a non-steroidal anti- inflammatory drug (NSAID), indomethacin, a selective inhibitor of COX-1, FR122047 or a selective COX-2 inhibitor, ...
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Dextromethorphan attenuated the higher vulnerability to inflammatory thermal hyperalgesia caused by prenatal morphine exposure in rat offspring
... P18 rats from four groups were used for plantar tests. Fifty μ l of carrageenan (20 mg/ml) was injected subcuta- neously via a 28-G needle into the plantar surface of the right hind paw. A plantar analgesiometer (7370, ...
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Anti nociceptive and desensitizing effects of olvanil on capsaicin induced thermal hyperalgesia in the rat
... alter thermal nociceptive thresholds, confirming its lack of pungency ...capsaicin-evoked thermal hyperalgesia ...on thermal paw withdrawal ...
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Anti-hyperalgesic properties of a flavanone derivative Poncirin in acute and chronic inflammatory pain models in mice
... duced thermal hyperalgesia and cold allodynia, animals were treated with poncirin (30 mg/kg, ...acute thermal hyperalgesia ...on thermal hyperalgesia, animals were treated daily ...
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The differential contribution of tumour necrosis factor to thermal and mechanical hyperalgesia during chronic inflammation
... threshold. Thermal hyperalgesia was assessed with the Hargreaves algometer test ...increasing thermal stimulus was delivered to the plantar sur- face of the hind ...
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EVALUATION OF ETHONOLIC EXTRACT OF OTTELIA ALISMOIDES (L.) PERS ON THE PAIN THRESHOLD RESPONSE IN STZ INDUCED DIABETIC NEUROPATHIC PAIN MODEL IN RATS
... The present study was designed to evaluate the Ethonolic extract of Ottelia alismoides on the pain threshold response in STZ induced diabetic neuropathic pain model in rats. To the overnight fasted rats, diabetes was ...
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MicroRNA-124 as a novel treatment for persistent hyperalgesia
... mice), thermal and mechanical hyper- algesia induced by intraplantar injection of inflammatory mediators were markedly prolonged ...ample, thermal hyperalgesia induced by a single intra- plantar ...
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Effect of Danggui Sini Decoction on the Behaviour and Dorsal Root Ganglion TRP Channel of Neuropathic Pain in CCI Rats
... inducing thermal hyperalgesia and mechanical ...on thermal hyperalgesia and mechanical hyperalgesia in CG rats may be realized by down- regulating the expression of ...
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AMELIORATIVE EFFECTS OF MURRAYA KOENIGII IN CHRONIC CONSTRICTION INJURY OF SCIATIC NERVE INDUCED NEUROPATHIC PAIN IN RATS
... (i.e., thermal hyperalgesia and cold allodynia) and biochemical ...like hyperalgesia and allodynia. CCI nerve injury produces robust thermal hyperalgesia and cold allodynia in the ...
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Antinociceptive effects of hydroalcoholic extract from Euterpe oleracea Mart (Açaí) in a rodent model of acute and neuropathic pain
... Methods: Antinociceptive effects of ASE were evaluated in the hot plate, formalin, acetic acid writhing, carrageenan, and neuropathic pain models, as well as in thermal hyperalgesia and [r] ...
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EVALUATION OF MODULATORY ROLE OF GABAPENTIN IN INCISIONAL PAIN AND INFLAMMATION
... behavior: thermal hyperalgesia [14,15] and cold allodynia [13, ...for thermal hyperalgesia test and eight (n=8) rats for cold allodynia ...The thermal hyperalgesia and cold ...
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<p>Contribution of GABAergic modulation in DRGs to electroacupuncture analgesia in incisional neck pain rats</p>
... that thermal hyperalgesia of the inci- sional neck region was significantly reduced by EA of LI18 and LI4–PC6, the same and neighboring neurosegmental stimulation, respectively, rather than by EA of ...
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EFFECT OF ZONISAMIDE ON CHRONIC CONSTRICTION INJURY INDUCED NEUROPATHIC PAIN IN MALE SD RATS
... Thermal hyperalgesia response was assessed according to the procedure described by Eddy and Leimbach [23]. The temperature of eddy’s hot plate was set at 55.0 ± 0.1°C. The operated rats was placed on the ...
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Micronized/ultramicronized palmitoylethanolamide displays superior oral efficacy compared to nonmicronized palmitoylethanolamide in a rat model of inflammatory pain
... and thermal hyperalgesia were markedly and significantly reduced by oral treatment with micronized PEA-m and ultramicronized PEA-um at each time point compared to nonmicronized ...
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Original Article Involvement of P2X7 receptors and downstream ERK pathways in chronic inflammatory pain
... reduced thermal allodynia and mechanical hyperalgesia in every phase of the response (p < ...ATP-induced thermal hyperalgesia and mechanical allodynia were dose-dependent (A and B); Effects ...
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Traumatic osteoarthritis-induced persistent mechanical hyperalgesia in a rat model of anterior cruciate ligament transection plus a medial meniscectomy
... Mechanical hyperalgesia was determined by quantifying the paw withdrawal threshold values using a von Frey test ...additionally, thermal hyperalgesia was determined by measuring the time to paw ...
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Pro-resolving mediator maresin 1 ameliorates pain hypersensitivity in a rat spinal nerve ligation model of neuropathic pain
... First, we examined whether MaR1 could attenuate mechani- cal allodynia and thermal hyperalgesia induced by SNL. There was a dramatic decrease of ipsilateral MWT and PWL from day 1, and the measurements ...
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