Tiotropium bromide
Inhibition of granulocyte migration by tiotropium bromide
... tropium bromide has additional anti-inflammatory cap- abilities due to reducing chemotactic activity of cultured AM in ...setup tiotropium bromide reduced LPS-mediated chemotaxis, possibly through an ...
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Suppression of IL-8 production from airway cells by tiotropium bromide in vitro
... of tiotropium bromide in a final volume of ...cases, tiotropium bromide was added to cell cultures 2 hours before the stimulation with ...
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Original Article The anti-inflammatory and anti-remodeling effect of tiotropium bromide in the subacute cigarette exposure mouse model
... Tiotropium bromide is a long-acting muscarinic antagonist (LAMA), which has been used in the treatment of ...COPD. Tiotropium prevents the binding of acetylcholine to muscarinic recep- ...of ...
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<p>Evaluation of rescue medication use and medication adherence receiving umeclidinium/vilanterol versus tiotropium bromide/olodaterol</p>
... or tiotropium bromide/olodaterol (TIO/OLO) between June 1, 2015 and November 30, 2016 (index date) with 12 months of pre- and post-index continuous ...
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Comparative effectiveness of budesonide/formoterol combination and tiotropium bromide among COPD patients new to these controller treatments
... and tiotropium bromide on time to first COPD exacerbation in the 12 months following the index ...LAMA; tiotropium patients were censored if they filled any other LAMA or any ...
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Tiotropium bromide inhibits TGF-ß-induced MMP production from lung fibroblasts by interfering with Smad and MAPK pathways <em>in vitro</em>
... Figure 4 Influence of tiotropium bromide hydrate (TBH) on mRNA expression for MMP-1, MMP-2, and TIMPs in lung fibroblasts after TGF- β stimulation.. International Journal of Chronic Ob[r] ...
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Tiotropium bromide exerts anti-inflammatory effects during resistive breathing, an experimental model of severe airway obstruction
... Tiotropium bromide inhalation prior to 50% of IRB did not affect total cell and macrophage number in ...3A). Tiotropium also attenuated the increase of IL-1 β and IL-6 following 50% IRB (P = ...
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The comparative analysis of salmeterol/fluticasone propionate combination and tiotropium bromide on lung function & health status changes, as well as prevention of exacerbations in patients with COPD.
... or tiotropium bromide & their comparison in the prevention of chronic obstructive pulmonary disease ...daily tiotropium bromide in patients with ...daily tiotropium bromide ...
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Triple therapy with salmeterol/fluticasone propionate 50/250 plus tiotropium bromide improve lung function versus individual treatments in moderate-to-severe Japanese COPD patients: a randomized controlled trial – Evaluation of Airway sGaw after treatment with tripLE
... and tiotropium bromide is commonly used to treat chronic obstructive pulmonary disease (COPD), but sparse efficacy data exist in COPD patients with fewer symptoms and with a lower dose of inhaled ...
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<sup>1</sup>H-NMR-based metabolic profiling of healthy individuals and high-resolution CT-classified phenotypes of COPD with treatment of tiotropium bromide
... The clinical characteristics of the study population are pre- sented in Table 2. There was only one set of data of the normal control group in FEV 1 /FVC%, FEV 1 /predicted %, and CAT scores respectively because the drug ...
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The evidence on tiotropium bromide in asthma: from the rationale to the bedside
... of tiotropium both in adult and younger patients for the chronic treatment of ...by tiotropium, its efficacy may not completely rely on the reduction of the airways’ cholinergic bronchomotor tone, but also ...
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A US database study characterizing patients initiating a budesonide–formoterol combination versus tiotropium bromide as initial maintenance therapy for chronic obstructive pulmonary disease
... or tiotropium therapy between March 1, 2009 and January 31, 2012 (intake ...or tiotropium group depending on their index prescription ...no tiotropium fills within 15 days of initiating BFC ...
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Long-acting muscarinic antagonist use in adults with asthma: real-life prescribing and outcomes of add-on therapy with tiotropium bromide
... prescribed tiotropium, although such an approach would almost certainly have led to the loss of unmatched but oth- erwise qualified patients prescribed tiotropium and thus to a smaller number and perhaps ...
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A RAPID AND STABILITY INDICATING RP HPLC METHOD FOR SIMULTANEOUS DETERMINATION OF TIOTROPIUM, FORMOTEROL AND CICLESONIDE IN A DRY POWDER INHALER
... of Tiotropium bromide, Formoterol Fumarate dehydrate and Ciclesonide were obtained as generous gifts from various pharmaceutical firms and was used as such without further ...
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Tiotropium in asthma: a systematic review
... either tiotropium bromide (18 μ g administered once daily from a metered dose inhaler) or a matched placebo before, secondly, receiving the other ...with tiotropium there were significant ...
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Clinical Study on the Usefulness of Tiotropium in Poorly Controlled Asthma Patients
... Asthma quality life was also assessed for all the patients. while assessing the Asthma Quality of Life Questionnaire (AQLQ) total mean of patient before starting Tiotropium bromide it was observed that 30 ...
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Tiotropium/olodaterol versus tiotropium in Japanese patients with COPD: results from the DYNAGITO study
... Background: The DYNAGITO study was a Phase IIIb, randomized, double-blind, multicenter, active-controlled, parallel-group, 52-week study designed to determine the efficacy and safety [r] ...
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The evolving role of tiotropium in asthma
... data. Tiotropium is the only LAMA currently approved for the treatment of asthma, and evidence from a large-scale clinical trial program , including several Phase III studies in adults, has demonstrated that ...
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Improvement in 24-hour bronchodilation and symptom control with aclidinium bromide versus tiotropium and placebo in symptomatic patients with COPD: post hoc analysis of a Phase IIIb study
... and tiotropium, as indicated by changes in RS-Breathlessness, RS-Cough and Sputum, and E-RS Total ...with tiotropium or placebo. Improvement over placebo and tiotropium was also observed in ...
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Butyltriphenylphosphonium bromide
... distances in the range 0.95–1.00 A Data collection: PROTEUM Bruker, 2002; cell refinement: SAINT-Plus Bruker, 2001; data reduction: SAINT-Plus; programs used to solve structure: SHELXS97[r] ...
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