Tissue factor pathway inhibitor (TFPI)
The carboxy terminus of tissue factor pathway inhibitor is required for interacting with hepatoma cells in vitro and in vivo
... Tissue factor pathway inhibitor (TFPI) is a plasma Kunitz-type serine protease inhibitor that directly inhibits coagulation Factor Xa and also inhibits tissue ...
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A preliminary estimation of tissue factor pathway inhibitor (TFPI) and protein C in patients with intracranial tumors
... additional TFPI and protein C properties have been discovered; namely their involvement in cell prolifera- tion and migration, as well as their participation in extra- cellular matrix ...assess tissue ...
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Promoter hypermethylation and silencing of tissue factor pathway inhibitor 2 in oral squamous cell carcinoma
... encoding tissue factor pathway inhibitor-2 ...[13], TFPI-2 is synthe- sized and secreted extracellularly mainly by keratino- cytes, fibroblasts, smooth-muscle cells, synoviocytes, and ...
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Tissue factor pathway inhibitor reduces mortality from Escherichia coli septic shock
... that tissue factor pathway inhibitor (TFPI) plays a significant role in vivo in regulating coagulation that results from exposure of blood to tissue factor after vascular ...
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Upregulated matrix metalloproteinase-2 and downregulated tissue factor pathway inhibitor-2 are risk factors for lymph node metastasis and perineural invasion in pancreatic carcinoma
... and tissue factor pathway inhibitor (TFPI)-2 is closely associated with tumorigenesis and tumor ...and TFPI-2 in identifying lymph node metastasis (LNM) and perineural invasion ...
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Tissue factor pathway inhibitor 2 is a novel inhibitor of matrix metalloproteinases with implications for atherosclerosis
... proteinase inhibitor tissue factor pathway inhibitor-2 (TFPI-2) can function as an MMP ...inhibitor. TFPI-2 diminished the ability of the interstitial collagenases ...
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Further insight into the heparin-releasable and glycosylphosphatidylinositol-lipid—anchored forms of tissue factor pathway inhibitor
... of tissue factor pathway inhibitor (TFPI) from human umbilical vein endothelial ...heparin-releasable TFPI activity (mU/mL), and error bars show 1 standard ...
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A comparative study of functional assays for tissue factor pathway inhibitor using normal plasma and clinical samples
... Tissue factor pathway inhibitor (TFPI) is a Kunitz-type inhibitor that regulates the initiation of tissue factor-mediated ...assess TFPI functional ...
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Factor VII deficiency rescues the intrauterine lethality in mice associated with a tissue factor pathway inhibitor deficit
... (a) factor VII (FVIIa) with its recep- tor and cofactor, tissue factor ...only tissue factor pathway inhibitor (TFPI) is known to inhibit the FVIIa/TF ...
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Anti tissue factor pathway inhibitor activity in patients with primary antiphospholipid syndrome
... the tissue factor (TF) pathway of ...TF pathway may be important in contributing to the hypercoagulability seen in aPS (Amengual et al, ...decreased tissue factor pathway ...
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The effects of antioxidant vitamins on the expression of tissue factor and tissue factor pathway inhibitor genes in human monocytic and endothelial cell lines
... Tissue factor pathway inhibitor is the primary physiological inhibitor that regulates tissue factor-induced blood coagulation (Pendurthi et al, ...1999). Tissue ...
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Renal expression of tissue factor pathway inhibitor and evidence for a role in crescentic glomerulonephritis in rabbits
... of TFPI followed by a constant infusion at a rate of ...Renal tissue and blood were collected 72 h af- ter initiation of GN and urine was collected for the preceding 24 ...
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The genetic variation rs6903956 in the novel androgen-dependent tissue factor pathway inhibitor regulating protein (ADTRP) gene is not associated with levels of plasma coagulation factors in the Singaporean Chinese
... Previously, our group had replicated the association between rs6903956 and CAD risk in the Singaporean Chinese and found that plasma lipids such as high dens- ity lipoprotein (HDL) cholesterol, low density lipoprotein ...
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Further investigations of lupus anticoagulant interference in a functional assay for tissue factor pathway inhibitor
... The effect of using three different sourcesof tissue factor recombinant,human brain and rabbit brain thromboplastinsin the TFPI assay was examined.. Of most significance was the apparent[r] ...
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Reduced expression of tissue factor pathway inhibitor-2 contributes to apoptosis and angiogenesis in cervical cancer
... that TFPI-2 expression in all patients with normal epithelial cells and CIN was positive, while that was activated in ...of TFPI-2 had a decreasing trend with the increase of malignant poten- tial of ...
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A novel anticoagulant activity assay of tissue factor pathway inhibitor I (TFPI)
... to TFPI free antigen, i.e. free, full-length TFPI, in plasma, but not with TFPI chromogenic substrate activity, TFPI total antigen or bound ...truncated TFPI (rTFPI 1)161 ...full-length ...
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Pro-coagulant activity during exercise testing in patients with coronary artery disease
... analyzed: tissue factor pathway inhibitor (TFPI) activity and antigen, prothrombin fragment 1 + 2 (F1 + 2), D-dimer and endogenous thrombin potential ...
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Reinhardt, Christoph (2007): Analyses on molecular mechanisms of activation of intravascular Tissue Factor. Dissertation, LMU München: Medizinische Fakultät
... Tissue factor pathway inhibitor-1 (TFPI) represents the main physiologic inhibitor of the coagulation ...coagulation pathway by first binding the circulating factors X / ...
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Original Article Correlation and prognostic significance of MMP-2 and TFPI-2 differential expression in pancreatic carcinoma
... and tissue factor pathway inhibitor (TFPI)-2 not only correlate with tumorigenesis, but also with tumor invasion and ...and TFPI-2 differential expression in pancreatic ...and ...
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Canalization effect in the coagulation cascade and the interindividual variability of oral anticoagulant response. a simulation Study
... the tissue factor (extrinsic) pathway kinetics by replacing, in the equations from [4] the coefficients cor- responding to the initial levels of factors II, V, VII, VIIa, VIII, IX, X, XI, ...
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