TISSUE-SPECIFICITY
Relationship between the tissue specificity of mouse gene expression and the evolutionary origin and function of the proteins
... and tissue expression other than through their common connection to recent rate of ...sue specificity in each of these sample sets is identical to the observed data and, because all genes in each bin have a ...
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Organ specific gene expression: the bHLH protein Sage provides tissue specificity to Drosophila FoxA
... Among the major questions in developmental biology are how cells are specified to form distinct cell types and how tissue-specific programs of gene expression are established and maintained. Key players in this ...
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Absence of Internal Ribosome Entry Site-Mediated Tissue Specificity in the Translation of a Bicistronic Transgene
... host specificity but not a tissue specificity of the IRES? It is not unheard of that host factors involved in IRES translation could vary between spe- ...
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In vivo activity of the hepatitis B virus core promoter: tissue specificity and temporal regulation.
... hepatic tissue required the combined action of both enhancers I and II, whereas the proximity of these two enhancers was insufficient to confer tissue specificity on Xp ...
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Promoter features related to tissue specificity as measured by Shannon entropy
... with tissue specificity and promoter structure are largely unknown beyond the CpG island ...for tissue specificity using genome-wide surveys of expression in many ...
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Transcriptional and structural impact of TATA initiation site spacing in mammalian core promoters
... with tissue-specific expression, we col- lected three sets of genes expected to be ubiquitously expressed: a set of 263 housekeeping genes from the HuGEIndex database (identified from microarray experi- ments) ...
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Acanthamoeba induces cell cycle arrest in host cells
... As indicated above, Acanthamoeba are known to produce two recognized diseases, GAE and keratitis. For biological relevance, we used a GAE isolate of Acanthamoeba belonging to the T1 genotype and studied its effect on ...
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Regulation of murine type 1 plasminogen activator inhibitor gene expression in vivo Tissue specificity and induction by lipopolysaccharide, tumor necrosis factor alpha, and transforming growth factor beta
... The regulation of type 1 plasminogen activator inhibitor (PAI-1) gene expression was studied in vivo employing a murine model system. Nuclease protection analysis revealed relatively high concentrations of PAI-1 mRNA in ...
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Digital gene expression analysis of the zebra finch genome
... In expression profiling it is preferable to use sequences from a non-normalized cDNA library to avoid bias in the estimates of expression individual genes [49]. In our case the only data available for gene expression in ...
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An Attenuated Strain of Enterovirus 71 Belonging to Genotype A Showed a Broad Spectrum of Antigenicity with Attenuated Neurovirulence in Cynomolgus Monkeys
... The binding activity and/or the amounts of anti-EV71 IgG and anti-EV71 IgM antibodies were measured by ELISA. Pre- FIG. 2. Experimental schedule, clinical symptoms, and virus excretion of cynomolgus monkeys inoculated ...
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Translational contributions to tissue specificity in rhythmic and constitutive gene expression
... v2.0.11) in order to estimate expressed transcript models in each organ (using Cufflinks v2.2.1 [38]). Transcriptome- mapping reads in the sequential alignment were counted towards their location into the 5′ UTR, CDS or ...
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Species and tissue specificity of prokinetic, laxative and spasmodic effects of Fumaria parviflora
... and/or tissue-selective effects of plant extracts have also been reported in earlier studies ...and/or tissue specific behavior of some plant materials is not ...
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Autoantibodies in rheumatoid arthritis and their clinical significance
... the specificity of RF as a diagnostic indicator for RA is substantially inferior to that of autoantibodies used for the diagnosis of other rheumatic autoimmune ...
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Detection of Helicobacter pylori DNA in Fecal Samples from Infected Individuals
... Patients undergoing upper endoscopy were recruited consecutively between August 1996 and December 1996 after giving informed consent according to our institution’s internal review board approval. ...
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Determining sensitivity and specificity of HER2 testing in breast cancer using a tissue micro array approach
... designed to be used for the purpose of quality control schemes. Rhodes et al . sent one slide containing four cell line blocks with graded and constant HER2 protein levels, two of these cell lines were previously ...
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The substrate specificity of hormone sensitive lipase from adipose tissue of the Antarctic fish Trematomus newnesi
... The failure of fully saturated and long-chain monounsaturated species of TAG to inhibit the hydrolysis of triolein was unanticipated and a novel feature of the present data set. The pronounced 3.7-fold increase in ...
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Restricted usage of T cell receptor V alpha V beta genes in infiltrating cells in the hearts of patients with acute myocarditis and dilated cardiomyopathy
... myocardial tissue of these ...antigen specificity of infiltrating T cells and persistence of viral genomes in the myocardial tissue, we analyzed the expression of T cell receptor (TCR) V alpha and V ...
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Tissue specific expression of the gene coding for human Clara cell 10 kD protein, a phospholipase A2 inhibitory protein
... constitutively at a very high level in the human respiratory epithelium, the 5' region of its gene may be useful in achieving organ-specific expression of recombinant DNA in gene therapy of diseases such as cystic ...
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Comparing Phylogenetic Codivergence between Polyomaviruses and Their Hosts
... or tissue culture, and little is known about infection in the natural ...from tissue cultures and is believed to be a contaminant with the calf serum, but no study we are aware of reported its natural ...
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Mitogen activated protein kinases: new signaling pathways functioning in cellular responses to environmental stress
... Enzymes in the p38 MAPK module are subject to dual phosphorylation at the Thr-Gly-Tyr motif and are generally activated by environmental stresses, including heat, osmotic and oxidative stresses, ionizing radiation and ...
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