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Tissue tropism

The Role of Interferon in Influenza Virus Tissue Tropism

The Role of Interferon in Influenza Virus Tissue Tropism

... differential tissue response may explain lung susceptibility in WT ...their tissue tropism by failure of HA cleavage outside the respiratory ...

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The Alpha/Beta Interferon Response Controls Tissue Tropism and Pathogenicity of Poliovirus

The Alpha/Beta Interferon Response Controls Tissue Tropism and Pathogenicity of Poliovirus

... for the study of poliovirus pathogenicity (21, 32). PVR-trans- genic mice exhibited a paralytic disease that resembled human poliomyelitis after poliovirus infection. PVR mRNA was de- tected in all tissues of ...

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Cell and tissue tropism of enterovirus 71 and other enteroviruses infections

Cell and tissue tropism of enterovirus 71 and other enteroviruses infections

... Infection of cells by a cell-free virus and virus spread from cell to cell are different processes that might de- pend on the presence of different cellular surface mole- cules. In infected organs, cell-to-cell spread ...

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Dynamic distribution and tissue tropism of classical swine fever virus in experimentally infected pigs

Dynamic distribution and tissue tropism of classical swine fever virus in experimentally infected pigs

... CSF is a severe swine disease in China [7], resulting in substantial economic loss. However, we are not fully understand the viral pathogenesis, multiplication, distri- bution, tissue tropism and excretion ...

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Baculovirus-Encoded Protein BV/ODV-E26 Determines Tissue Tropism and Virulence in Lepidopteran Insects

Baculovirus-Encoded Protein BV/ODV-E26 Determines Tissue Tropism and Virulence in Lepidopteran Insects

... sue tropism in host insect ...NPV’s tissue tropism quantitatively, we first measured mRNA levels of viral genes in 16 tissues from ...the tissue tropism of ...

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A Single Mutation at Position 156 in the Envelope Protein of Tembusu Virus Is Responsible for Virus Tissue Tropism and Transmissibility in Ducks

A Single Mutation at Position 156 in the Envelope Protein of Tembusu Virus Is Responsible for Virus Tissue Tropism and Transmissibility in Ducks

... ABSTRACT Duck Tembusu virus (TMUV), like other mosquito-borne flaviviruses, such as Japanese encephalitis virus, West Nile virus, and Bagaza virus, is able to transmit vector-independently. To date, why these flaviviruses ...

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Pathology and tissue tropism of natural West Nile virus infection in birds: a review

Pathology and tissue tropism of natural West Nile virus infection in birds: a review

... West Nile virus belongs to the genus Flavivirus of the family Flaviviridae. It has been serologically classified within the Japanese encephalitis antigenic group. The viral positive sense single-stranded RNA genome en- ...

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Characterization of Tissue Tropism Determinants of Adeno-Associated Virus Type 1

Characterization of Tissue Tropism Determinants of Adeno-Associated Virus Type 1

... The N terminus of VP1 does not contribute to AAV1 tissue tropism for muscle. The first two vectors tested were pH221- 1-351 and pH221-352-736. The plasmid pH221-1-351 carried a hybrid cap gene with amino ...

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Structural Determinants of Tissue Tropism and In Vivo Pathogenicity for the Parvovirus Minute Virus of Mice

Structural Determinants of Tissue Tropism and In Vivo Pathogenicity for the Parvovirus Minute Virus of Mice

... Viral tissue tropism and pathogenesis are highly dependent on well-orchestrated and defined interactions that occur be- tween the viral pathogen and its ...in tissue tropism and in vivo ...

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Differences in the tissue tropism to chicken oviduct epithelial cells between avian coronavirus IBV strains QX and B1648 are not related to the sialic acid binding properties of their spike proteins

Differences in the tissue tropism to chicken oviduct epithelial cells between avian coronavirus IBV strains QX and B1648 are not related to the sialic acid binding properties of their spike proteins

... The avian coronavirus (AvCoV) infectious bronchitis virus (IBV) is a major poultry pathogen. A characteristic feature of IBV is the occurrence of many different strains belonging to different serotypes, which makes a ...

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Natural Hendra virus infection in flying-foxes - tissue tropism and risk factors

Natural Hendra virus infection in flying-foxes - tissue tropism and risk factors

... excretion, tissue tropism and transmission of infection in both experimentally and naturally infected flying-foxes [2,9 – ...vascular tissue of experimentally infected P ...placental tissue, ...

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Human H7N9 and H5N1 Influenza Viruses Differ in Induction of Cytokines and Tissue Tropism

Human H7N9 and H5N1 Influenza Viruses Differ in Induction of Cytokines and Tissue Tropism

... The novel avian-origin H7N9 pandemic represents a serious threat to public health. The ability of H7N9 to cause serious lung pathology, leading in some cases to the development of acute respiratory distress syndrome, is ...

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Secondary Infections, Expanded Tissue Tropism, and Evidence for Malignant Potential in Immunocompromised Mice Infected with Mus musculus Papillomavirus 1 DNA and Virus

Secondary Infections, Expanded Tissue Tropism, and Evidence for Malignant Potential in Immunocompromised Mice Infected with Mus musculus Papillomavirus 1 DNA and Virus

... mice and in SCID SHO mice to determine its potential as an ani- mal model for papilloma disease. Our goals were to generate in- fections via DNA, to isolate and passage virus that might result from these infections, and ...

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Tissue Tropism of Swine Influenza Viruses and Reassortants in Ex Vivo Cultures of the Human Respiratory Tract and Conjunctiva

Tissue Tropism of Swine Influenza Viruses and Reassortants in Ex Vivo Cultures of the Human Respiratory Tract and Conjunctiva

... the tissue tropism of the H1N1pdm and human seasonal H1N1 virus in primary in vitro and ex vivo cultures of the human respiratory tract was similar except that only H1N1pdm infected and replicate in human ...

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Infection dynamics and tissue tropism of Parvicapsula pseudobranchicola (Myxozoa: Myxosporea) in farmed Atlantic salmon (Salmo salar)

Infection dynamics and tissue tropism of Parvicapsula pseudobranchicola (Myxozoa: Myxosporea) in farmed Atlantic salmon (Salmo salar)

... In pseudobranchs of Atlantic salmon, mature P. pseu- dobranchicola spores have been observed some 4 – 8 months after sea-transfer [2, 8, 19, 23]. However, the time needed for the parasite to develop spores is poorly ...

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In Vivo Imaging with Bioluminescent Enterovirus 71 Allows for Real-Time Visualization of Tissue Tropism and Viral Spread

In Vivo Imaging with Bioluminescent Enterovirus 71 Allows for Real-Time Visualization of Tissue Tropism and Viral Spread

... ABSTRACT Hand, foot, and mouth disease (HFMD) is a reemerging illness caused by a variety of enteroviruses. The main causative agents are enterovirus 71 (EV71), coxsacki- evirus A16 (CVA16), and, most recently, ...

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Experimental Toxoplasmosis in Rats Induced Orally with Eleven Strains of Toxoplasma gondii of Seven Genotypes: Tissue Tropism, Tissue Cyst Size, Neural Lesions, Tissue Cyst Rupture without Reactivation, and Ocular Lesions.

Experimental Toxoplasmosis in Rats Induced Orally with Eleven Strains of Toxoplasma gondii of Seven Genotypes: Tissue Tropism, Tissue Cyst Size, Neural Lesions, Tissue Cyst Rupture without Reactivation, and Ocular Lesions.

... studied tissue tropism in the brains of chronically infected rodents, particularly the amygdalar region (Table 1, ...found tropism to the amygdaloid [21] or mid brain regions ...of tissue ...

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Murine cytomegalovirus with a deletion of genes spanning HindIII-J and -I displays altered cell and tissue tropism.

Murine cytomegalovirus with a deletion of genes spanning HindIII-J and -I displays altered cell and tissue tropism.

... Murine cytomegalovirus (MCMV) gene products dispensable for growth in cell culture are likely to have important functions within the infected host, influencing tissue tropism, dissemination, or ...

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The Pulmonary Localization of Virus-Specific T Lymphocytes Is Governed by the Tissue Tropism of Infection

The Pulmonary Localization of Virus-Specific T Lymphocytes Is Governed by the Tissue Tropism of Infection

... lung tissue following systemic versus localized respiratory viral ...lung tissue following a pulmonary infection with a pathogen ca- pable of replicating ...lung tissue following in- fection with a ...

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Neutralization-resistant variants of infectious hematopoietic necrosis virus have altered virulence and tissue tropism.

Neutralization-resistant variants of infectious hematopoietic necrosis virus have altered virulence and tissue tropism.

... Similar studies with human immunodeficiency virus 3, 4, 12, 24, 26, influenza virus C 25, and lymphocytic choriomeningitis virus 19 have shown that single amino acid changes in the viral[r] ...

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