TNF - Tumor Necrosis Factor
Modulation of Anti-Tumor Necrosis Factor Alpha (TNF-α) Antibody Secretion in Mice Immunized with TNF-α Kinoid
... Tumor necrosis factor alpha (TNF-␣) blockade is an effective treatment for patients with TNF-␣-dependent chronic inflamma- tory diseases, such as rheumatoid arthritis, Crohn’s disease, ...
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A Possible Mechanism of Cisplatin Induced Tumor Necrosis Factor (TNF) α Production in Murine Macrophages
... dose-limiting factor of this agent, develops due to the secretion of tumor necrosis factor-α (TNF-α) from macrophages; however, the precise mechanisms are still ...cisplatin-induced ...
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Roles of Tumor Necrosis Factor Alpha (TNF-α) and the p55 TNF Receptor in CD1d Induction and Coxsackievirus B3-Induced Myocarditis
... reduced. Tumor necrosis factor alpha (TNF- ␣ ) concentrations in the heart were increased in all infected mice, but cytokine levels were highest in mice given the larger virus ...inocula. ...
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Poliovirus Protein 3A Inhibits Tumor Necrosis Factor (TNF)-Induced Apoptosis by Eliminating the TNF Receptor from the Cell Surface
... to tumor necrosis factor (TNF)-induced ...of TNF signaling, including the lack of activation of NF- B, due to elimination of the TNF receptor from the cell ...in TNF ...
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Caffeic Acid Inhibited Receptor Activator of Nuclear Factor κB Ligand (RANKL)- Tumor Necrosis Factor (TNF) α-TNF Receptor Associated Factor (TRAF) 6
... nuclear factor κB ...Since tumor necrosis factor (TNF) receptor-associated factor 6 (TRAF6) plays important role in osteoclastogenesis, we applied TRAF6- trasfected RAW264 cells ...
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Anti-tumor necrosis factor (TNF) drugs for the treatment of psoriatic arthritis: an indirect comparison meta-analysis
... anti-tumor necrosis factor; CI, confidence interval; ETN, etanercept; GOL, golimumab; HAQ, Health Assessment Questionnaire; INF, infliximab; MD, mean difference; PASI, Psoriasis Area and Severity ...
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Human Cytomegalovirus Infection Inhibits Tumor Necrosis Factor Alpha (TNF-α) Signaling by Targeting the 55-Kilodalton TNF-α Receptor
... for tumor necrosis factor alpha (TNF- ␣ ), one of the receptors for a potent cytokine involved in eliciting a wide spectrum of cellular responses, including antiviral ...of TNF- ␣ ...
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Hepatitis C Virus Core Protein Binds to the Cytoplasmic Domain of Tumor Necrosis Factor (TNF) Receptor 1 and Enhances TNF-Induced Apoptosis
... of tumor necrosis factor receptor (TNFR) ...to TNF-induced apoptosis, as determined by the TNF cytotoxicity or annexin V apoptosis ...to TNF by the viral core protein was not due ...
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Distinct domains of M-T2, the myxoma virus tumor necrosis factor (TNF) receptor homolog, mediate extracellular TNF binding and intracellular apoptosis inhibition.
... virus tumor necrosis factor (TNF) receptor homolog, M-T2, is expressed both as a secreted glycoprotein that inhibits the cytolytic activity of rabbit TNF- a and as an endoglycosidase ...
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Tumor necrosis factor (TNF) is an important cytokine
... Induction and maintenance therapy with adalimumab was generally well-tolerated in this study. Rates of dis- continuation due to adverse events were low and were greater in placebo-treated patients versus those receiving ...
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How To Treat A Tumor Necrosis Factor (Tnf) Blocker
... 5.2 Malignancies Malignancies, some fatal, have been reported among children, adolescents, and young adults who received treatment with TNF-blocking agents (initiation of therapy ≤ 18 years of age), of which ...
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CiteSeerX — MINIREVIEW Tumor Necrosis Factor (TNF)– � and TNF Receptors in Viral Pathogenesis (44487)
... So far more than 10 different human caspases have been discovered and are known by a variety of different names (66–68). All caspases are synthesized as proenzymes and are processed to remove an NH 2 -terminal prodomain ...
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Mouse TNF-α(Tumor Necrosis Factor Alpha) ELISA Kit
... Sample Dilution The user should estimate the concentration of target protein in the test sample, and select a proper dilution factor to make the diluted target protein concentration fall in the optimal detection ...
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Release of soluble receptors for tumor necrosis factor (TNF) in relation to circulating TNF during experimental endotoxinemia
... J Clin Invest. 1992;90(2):533-536. https://doi.org/10.1172/JCI115891. Serial plasma samples from human volunteers obtained after intravenous administration of Escherichia coli endotoxin were analyzed for the presence of ...
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On the binding of tumor necrosis factor (TNF) to heparin and the release in vivo of the TNF binding protein I by heparin
... of TNF-BP-I into the circulation with intermittent injections of heparin indicates that TNF-BP-I is present both in a storage pool and in a circulating ...of TNF-BP-I was not explained; TNF-BP ...
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Tumor necrosis factor (TNF) receptor (TNFR) associated factor 6 (TRAF6) is a unique member
... One method of inhibiting TRAF signaling is to block TRAF-receptor interaction with short pep- tides or small molecules. Based on the crystal structure of TRAF6-TRANCE-R complex, cell permeable TRAF6-interacting decoy ...
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CiteSeerX — Tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) and TNF- promote the NF-B-dependent
... Remarkably, TNF- ␣ and TRAIL induced a significant mod- ulation of the expression of TRAIL receptors, and the most prominent modification was the robust up-regulation of TRAIL- ...Similarly, TNF- ␣ has been ...
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Polymorphism of tumor necrosis factor alpha (TNF-alpha) gene promoter, circulating TNF-alpha level, and cardiovascular risk factor for ischemic stroke
... serum TNF-α level was asso- ciated with higher risk of ischemic stroke in the Chinese Han ...the TNF-α was not asso- ciated with risk of stroke in a British prospective study ...that TNF-α was linked ...
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CiteSeerX — Rapid Induction of Apoptosis by Combination of Flavopiridol and Tumor Necrosis Factor (TNF)- � or TNF-related Apoptosis-inducing Ligand in Human
... Fig. 5. Flavopiridol prevents TNF- ␣-induced NF-B-regulated transcription. A, A549 cells transiently transfected with pNF- B-luciferase plasmid were equally dispensed into separate culture plates, and each of ...
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Functional switching of macrophage responses to tumor necrosis factor alpha (TNF alpha) by interferons Implications for the pleiotropic activities of TNF alpha
... of TNF alpha in stimulating the synthesis of two macrophage gene products, namely IGF-1, a growth factor implicated in wound repair and fibrosis, and complement component factor B (Bf), an ...
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