TNF–tumour necrosis factor
Bone marrow characterization in COPD: a multi-level network analysis
... cells; TNF: Tumour necrosis factor; VEGF: Vascular endothelial growth fac- tor; HGF: Hepatocyte growth factor; IL: Interleukin; RBC: Red blood cells; WBC: White blood cells; Lympho: ...
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Veritable antiviral capacity of natural killer cells in chronic HBV infection: an argument for an earlier anti virus treatment
... interferon; TNF: tumour necrosis factor; IT: immune tolerant phase; IA: immune active phase; IC: inactive CHB phase; GZ: grey zone; ALT: alanine aminotransferase; ULN: upper limit of normal; ...
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Polymorphism in the tumour necrosis factor receptor II gene is associated with circulating levels of soluble tumour necrosis factor receptors in rheumatoid arthritis
... the TNF-RII gene occurs within the fourth cysteine-rich domain of the extracellu- lar domain, close to a point where the proteolytic cleavage site for TACE is thought to lie ...bound TNF-RII by TACE might ...
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Estimating the returns to United Kingdom publicly funded musculoskeletal disease research in terms of net value of improved health outcomes
... anti-tumour necrosis factor drugs; ARUK: Arthritis Research UK; bDMARDs: biologic disease-modifying anti rheumatic drugs; cDMARDs: conventional disease- modifying anti rheumatic drugs; CPRD: Clinical ...
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Patients with Arthritis Undergoing Surgery: How Should We Manage Tumour Necrosis Factor Blocking Agents Perioperatively? A Systematic Literature Review
... on TNF-BA with patients not receiving this treatment [“yes/no” studies; ...received TNF-BA: in these studies one group of patients continued treatment during surgery, while patients in the other group ...
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TNF-dependent regulation and activation of innate immune cells are essential for host protection against cerebral tuberculosis
... cytokine tumour necrosis factor (TNF) plays a critical role in the initial and long-term host immune protection against Mycobacterium tuberculosis ...of TNF, in particular ...
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Association of tumour necrosis factor-α (TNF-α) gene polymorphisms (-308 G>A and -238 G>A) and the risk of severe dengue: a meta-analysis and trial sequential analysis
... that TNF- α -308 G>G genotype and allele G confer susceptibility to symptomatic dengue, while TNF- α -308 G>A genotype and allele A confer protection ...between TNF-α- 308 G>A and the DHF ...
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Advanced glycation endproducts are increased in rheumatoid arthritis patients with controlled disease
... AF: Auto Fluorescence; AGEs: advanced glycation endproducts; Anti-CCP: anti-cyclic citrullinated protein; Anti-TNF: anti-tumour necrosis factor; a.u.: arbitrary units; BMI: body mass index; ...
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The effects of highly active antiretroviral therapy on the serum levels of pro-inflammatory and anti-inflammatory cytokines in HIV infected subjects
... Both innate and adaptive immune responses are raised during HIV infection. CD4+ T helper cells play a vital role in the immune system by secreting cytokines, which regu- late the immune response. Cytokines are secreted ...
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Coexpression and interaction of CXCL10 and CD26 in mesenchymal cells by synergising inflammatory cytokines: CXCL8 and CXCL10 are discriminative markers for autoimmune arthropathies
... Detection of CD26 by Fluorescence-activated cell sorting (FACS) analysis. Expression of CD26 was detected by FACS analysis. (a) Expression level of CD26 on unstimulated fibroblasts. Background staining with secondary ...
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Commercially Available Antibodies to Human Tumour Necrosis Factor-α Tested for Cross-Reactivity with Ovine and Bovine Tumour Necrosis Factor-α using Flow Cytometric Assays
... bovine TNF- α in the serum or milk samples ...pg TNF- α /ml, respectively, and 2 pooled serum samples not containing any TNF- α (0 pg/ml), as previously deter- mined with ...bovine TNF- α in ...
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Gut microbiota associated with HIV infection is significantly enriched in bacteria tolerant to oxygen
... increased tumour necrosis factor (TNF)/ IL-10 ratio have been associated with increased Enterobacteriaceae 15 17 and Eubacterium biforme, 18 respectively, and TCD8+ cell activation was ...
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The role of synovial macrophages and macrophage produced cytokines in driving aggrecanases, matrix metalloproteinases, and other destructive and inflammatory responses in osteoarthritis
... of tumour necrosis factor (TNF)-α and/or inter- leukin (IL)-1 on the expression of matrix metalloproteinases (MMPs), tis- sue inhibitors of MMP (TIMPs), and link protein in osteoarthritis ...
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Systematic review: psychological morbidity in young people with inflammatory bowel disease - risk factors and impacts
... Abbreviations: abbPCDAI, Abbreviated Pediatric Crohn’s Disease Activity Index; AMBS, Adolescent medication barriers scale; Anti-TNF, Anti-Tumour necrosis factor; API, Abdominal Pain I[r] ...
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Chlamydia pneumoniae-induced tumour necrosis factor alpha responses are lower in children with asthma compared with non-asthma
... (n=19) (figure 2A) and subjects without asthma (n=6) (figure 2B) were infected ±C. pneumoniae (MOI=0.1), and then cultured with ciprofloxacin (0.1 µg/mL), azithromycin (0.1 µg/mL) or doxycycline (0.1 µg/mL). Levels of ...
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Effects of Adalimumab, an Anti-tumour Necrosis Factor-Alpha (TNF-α) Antibody, on Obese Diabetic Rats
... of TNF-α was presented by Hotamisligil et ...that TNF-α is also expressed in human adipose tissue, and further, that its plasma concentration in obese subjects is decreased following weight loss ...between ...
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Role of Tumour Necrosis Factor (TNF) and Glycosylphosphatidylinositol (GPI) as Important Mediators in the Pathogenesis of Malaria Infection
... that immunization of mice with highly purified malaria GPI prepared from the mature MSP-2 led to a serological anti-GPI response with T- independent features. These anti-GPI sera were able even at high titration to ...
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The role of death receptors in ER stress and Inflamation
... The tumour necrosis factor receptor (TNFR) family of cell surface receptors have been shown over the past two decades to induce inflammation, cellular proliferation, survival, differentiation or ...
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The effects of pharmacological interventions on quality of life and fatigue in sarcoidosis: a systematic review
... anti-tumour necrosis factor (TNF)- α therapy (adalimumab, etanercept or infliximab), one study evaluated anti-TNF-α and anti-interleukin (IL)-12 and -23 therapy (golimumab and ...
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... (IL-), tumour necrosis factor- α (TNF- α), and the an- ti-infl ammatory cytokine interleukin- (IL-) have been detected in human atherosclerotic plaques ...
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