Tolerability and Safety
EVALUATION OF THE EFFICACY, TOLERABILITY AND SAFETY OF A COMBINATION OF ESOMEPRAZOLE AND DOMPERIDONE IN GERD
... This prospective studywas conducted between JUNE 2015 and JUNE 2016 in 137 patients in department of medicine, Sree Balaji Medical College & Hospital, Chennai, India with dyspepsia associated with GERD (diagnosed as ...
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An open-label, one-year, noncomparative study to evaluate the safety and tolerability of intravitreal pegaptanib sodium in patients with diabetic macular edema
... This Phase IIIb study was designed to extend and fur- ther evaluate the safety and tolerability of pegaptanib in patients with DME. However, soon after study initiation, the sponsor decided to withdraw the ...
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Effectiveness, safety and tolerability of botulinum toxin in focal hyperhidrosis and dynamic facial wrinkles
... EFFECTIVENESS, SAFETY AND TOLERABILITY OF BOTULINUM TOXIN IN FOCAL HYPERHIDROSIS & DYNAMIC FACIAL WRINKLES This dissertation is submitted to THE TAMILNADU DR.M.G.R.MEDICAL UNIVERSITY In [r] ...
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Feasibility, safety and tolerability of accelerated dobutamine stress echocardiography
... Dobutamine stress echocardiography (DSE) is commonly used to assess the extent, location, and severity of coro- nary artery disease (CAD) and myocardial viability [1-6]. The duration and infusion dose of dobutamine for ...
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The safety and tolerability profile of bilastine for chronic urticaria in children
... Paediatric Committee [15]. Only bilastine and rupata- dine have been investigated in such a plan, among the second generation antihistamines. A phase III, double- blind, randomized, placebo-controlled, parallel-group ...
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Efficacy, safety, and tolerability of abatacept in the management of rheumatoid arthritis
... to at least 1 strain and 50% responded to 2 or 3 strains. Overall, the immunogenicity of abatacept appears to be low. Whether the development of antibodies directed against the whole molecule or against the CTLA-4 ...
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Assessing the general safety and tolerability of vildagliptin: value of pooled analyses from a large safety database versus evaluation of individual studies
... assessing safety and tolerability and can lead to difficult-to-interpret or even misleading ...the safety surveillance measures, and, in particular, the comparator chosen for individual studies can ...
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A study of safety and tolerability of rotatory vestibular input for preschool children
... The safety and tolerability of rotatory vestibular stimulation input data obtained in this study can provide useful reference data for therapists using sensory integration ...
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Mefloquine safety and tolerability in pregnancy: a systematic literature review
... the safety of MQ use in pregnant women in terms of pregnancy outcomes and drug ...the safety of MQ (used alone or combined with other anti-malarials) in pregnant women for treatment and/or prevention of ...
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Evaluation of the Safety, Tolerability, and Immunogenicity of an Oral, Inactivated Whole-Cell Shigella flexneri 2a Vaccine in Healthy Adult Subjects
... excellent safety profile observed for the vaccine, since persistent increases would have likely been associated with a higher degree of systemic and/or local gastroin- testinal side ...on safety and ...
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Clinical potential of apremilast in the treatment of psoriatic arthritis
... transcription such as PDE4-inhibiting compounds, being PDE4 involved in degrading cAMP and therefore altering the activity of transcription factors such as CREB and NF- κ B. The reduction of the inflammatory mediators ...
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Clinical utility, safety, and tolerability of ezogabine (retigabine) in the treatment of epilepsy
... to be minor or moderate, sometimes only involving labora- tory abnormalities on urinalysis and rarely leading to dis- continuation from the trial. However, urinary hesitancy and retention can be clinically significant ...
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Safety and tolerability of antipsychotics: focus on amisulpride
... efficacy, tolerability, and safety profiles of these agents seem to be superior to that of the classical ...the safety of the atypical antipsychotics is related to their propensity to induce weight ...
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Immunogenicity, Safety, and Tolerability of a Hexavalent Vaccine in Infants
... All randomly assigned participants who received $1 dose of study vaccine and had safety follow-up were included in the safety analysis. The AE and fever profiles were described for study vaccines after each ...
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Specific safety and tolerability considerations in the use of anticonvulsant medications in children
... The goal of antiepileptic medication is to achieve seizure freedom, and thus minimize the comorbidities associated with epilepsy, such as injury, sudden unexplained death in epilepsy, intellectual disability, and ...
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Safety and tolerability of adjunctive rosiglitazone treatment for children with uncomplicated malaria
... the safety and tolerability of the drug, may not be sufficiently informative of the potential that the drug has to impact the course of ...the safety of rosiglitazone in children and is a ...
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Vol 28, No 5 (2015)
... However, safety and tolerability issues were raised in all these studies and need also to be ...during safety follow-up and another patient was diagnosed with presumed autoimmune pancytopenia 19 ...
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Safety and tolerability of inhalational anticholinergics in COPD
... raised some safety concerns. A large trial, comparing different doses and delivery methods of inhaled tiotropium, is ongoing to determine the effect on mortality. As clinical trials may not comprehensively ...
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Targeting of interleukin-17 in the treatment of psoriasis
... efficacy, safety, and tolerability of brodalumab, secukinumab, and ixekizumab in clinical trials; and possible differences between targeting of the IL-17A receptor and targeting of the IL-17A ...
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Comparison of esophageal placement of Bravo capsule system under direct endoscopic guidance with conventional placement method
... In addition, data were also obtained on patient experience of the procedure, willingness to repeat the procedure if needed, and number of workdays off following the procedure. Patient experience with the procedure of ...
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