Toll-like receptor (TLR)
Toll like receptor downstream signaling
... Drosophila, Toll was initially identified as an essential protein for the determination of dorsoventral polarity during early ...mutant Toll gene are highly susceptible to fungal infection because of a ...
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Signal transduction by the lipopolysaccharide receptor, Toll like receptor 4
... interleukin-1 receptor-associated kinase; IRF, interferon response factor; ISRE, interferon-sensitive response element; LPS, lipopoly- saccharide; LBP, LPS-binding protein; Mal, MyD88 adapter like; MAPK, ...
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MicroRNAs and Toll-like Receptor/Interleukin-1 Receptor Signaling
... disorders like rheumatoid arthritis, systemic lupus erthematosus, experimental autoimmune encephalomyelitis, and inflammatory ...on toll-like receptor (TLRs) and interleukin-1 β (IL-1 β ) ...
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Association between Toll Like Receptor 4 (Thr399Ile and Asp299Gly), Toll Like Receptor 2 196 174 Deletion Polymorphisms with cryptosporidiosis
... of Toll-Like Receptors [TLR] 2 (-196 to -174 del) and TLR 4 (Asp299Gly, Thr399Ile) in Cervical Cancer Susceptibility in North Indian ...the Toll-Like Receptor 2 Subfamily and Risk of ...
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Toll-like receptor 2 and type 2 diabetes
... 45. Ryu JH, Yoo JY, Kim MJ, Hwang SG, Ahn KC, Ryu JC, Choi, M.K, Joo, J.H, Kim, C.H, Lee, S.N, Lee, W.J, Kim, J., Shin, D. M, Kweon, M.N, Bae, Y.S. and Yoon, J.H. Distinct TLR-mediated pathways regulate house dust ...
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Alternate transcription of the Toll like receptor signaling cascade
... the Toll-like receptor (Tlr) cascade has been shown to dramatically alter the signaling capacity of inflammatory cells, but it is not known how common this mechanism ...the Toll-like ...
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Genipin Attenuates Sepsis by Inhibiting Toll-Like Receptor Signaling
... failure. Toll-like receptor (TLR) signaling is crucial for induction of hyperinflammatory responses and tissue injury during ...the Toll/interleukin-1 receptor domain-containing adaptor ...
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Toll-like receptor expression and function in airway epithelial cells
... I NTRODUCTION The lung is a unique organ. Although constantly exposed to inhaled contaminants and microbes pre- sent in the air breathed, up to 20,000 liters each day, it can effectively maintain a sterile environment. ...
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Emerging role of Toll-like receptor 4 in hepatocellular carcinoma
... Recurrence is quite common in patients with HCC who have had a radical resection, and the survival rate is 30%–40% at 5 years postsurgery. 2 This is because those malignant cells developed intricate mechanisms that ...
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Are Toll-like receptor gene polymorphisms associated with prostate cancer?
... Abbreviations: CI, confidence interval; NA, no association; OR, odds ratio; SNP, single nucleotide polymorphism; TLR, Toll-like receptor; US, United States. on large samples in various countries, ...
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Signaling Flux Redistribution at Toll-Like Receptor Pathway Junctions
... In Toll-like receptor (TLR) 4 signaling, which branches into MyD88- and TRAM-dependent pathways upon lipopolysaccharide (LPS) stimulation, we investigated the gain or loss-of-function mutations of ...
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Structural characterisation of Toll-like receptor 1 (TLR1) and Toll-like receptor 6 (TLR6) in elephant and harbor seals
... (2016) 'Structural characterisation of Toll-like receptor 1 (TLR1) and Toll-like receptor 6 (TLR6) in elephant and harbor seals', Veterinary Immunology and.. Immunopathology, 169, 10-14[r] ...
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Expression and activation of toll-like receptor 3 and toll-like receptor 4 on human corneal epithelial and conjunctival fibroblasts
... Interestingly, activation of HCE TLR3 and TLR4 by poly I:C and LPS, while stimulating secretion of pro- inflammatory cytokines and the up-regulation of their respective genes, was found to decrease TLRs surface ex- ...
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Relationship between toll-like receptor 2 Arg677Trp and Arg753Gln and toll-like receptor 4 Asp299Gly polymorphisms and cytomegalovirus infection
... 36. Wang JJ, Xia X, Tang SD, Wang J, Deng XZ, Zhang Y, et al. Meta-analysis on the associations of TLR2 gene polymorphisms with pulmonary tuberculosis sus- ceptibility among Asian populations. PLoS One 2013;8:e75090. 37. ...
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Toll like receptor polymorphisms in malaria endemic populations
... mammalian toll-like receptors: gene structure, expression, and evolu- ...the Toll-like receptor 9 gene (TLR9): frequen- cies, pairwise linkage disequilibrium, and haplotypes in three ...
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Toll-like receptor polymorphisms in malaria-endemic populations
... mammalian toll-like receptors: gene structure, expression, and evolu- ...the Toll-like receptor 9 gene (TLR9): frequen- cies, pairwise linkage disequilibrium, and haplotypes in three ...
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Functional Consequences of Toll-like Receptor 4 Polymorphisms
... Toll-like receptor 4 (TLR4) is an important pathogen recognition receptor that recognizes mainly lipopolysaccharide (LPS) of Gram- negative bacteria, but also structures from fungal and ...
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Functional consequences of toll-like receptor 4 polymorphisms.
... Toll-like receptor 4 (TLR4) is an important pathogen recognition receptor that recognizes mainly lipopolysaccharide (LPS) of Gram- negative bacteria, but also structures from fungal and ...
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Investigation of toll-like receptor tolerance in the regulation of inflammation
... of Toll-like receptor induced pro-inflammatory gene expression, we found no significant difference in the expression of TNF-α, IL- 6, CXCL1 and IL-1β between DSS-treated WT and Bcl-3 -/- mice (Figure ...
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Polymorphisms in toll-like receptor 4 and toll-like receptor 9 influence viral load in a seroincident cohort of HIV-1-infected individuals.
... Toll-Like Receptor 9; Toll-Like Receptor 4 INTRODUCTION Persons with HIV-1 infection exhibit a high degree of variability in their rate of progression to immunodeficiency and ...
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