TRANSCRIPTION FACTOR
Transcription factor omics
... • The combined analysis of quantitative transcriptome and interactome data provide unique insights into protein function. Transcription factor ‘omics’.[r] ...
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Transcription Factor Occupancy in Differentiating Skeletal Muscle
... positive-acting transcription factor, occupies cis-elements around genes that need to be expressed in differentiating muscle (including those that are not differentiation-specific), and contributes to their ...
137
Transcription factor interplay during Drosophila haematopoiesis
... (Lz) transcription factor is directly involved in maintaining the expression of the lineage-specific partner and in coordinating the expression of a wide array of differentiation markers (Ferjoux et ...RUNX ...
9
Molecular mechanisms of OLIG2 transcription factor in brain cancer
... through transcription regulation [72], mitogen activated protein kinase kinase kinase 14 (MAP3K14), which stimulates NF-kappa-B transcriptional activation and regulation via noncanonical pathways [73], mitogen ...
28
Evolution of the activation domain in a Hox transcription factor
... of transcription regulatory domains is often complicated by the low sequence complexity and high mutation rates of intrinsically disordered protein ...Hox transcription factor Ultrabithorax (Ubx), ...
10
Transcription factor haploinsufficiency: when half a loaf is not enough
... detection. Transcription factors regulate gene expression by binding the target gene promoter and turn the target gene “on” or “off”; in a particular cell, target gene expression is an all-or-none phe- ...nomenon. ...
6
Expression and developmental requirement for transcription factor Sp2
... Sp4 expression are detected within the entire central nervous system as well as other neural structures including, the retina, trigeminal ganglia, spinal ganglia and developing cranial nerves. In addition to the nervous ...
205
DNA-Mediated Oxidation of Transcription Factor p53
... Transcription factor p53 was initially thought to be an oncogene, due to its marked upregulation in numerous human ...a transcription factor whose mutation leads to a predisposition to ...
139
Nac1 interacts with the POZ-domain transcription factor, Miz1.
... Abbreviations: BEN, B-cell translocation gene 3 associated nuclear protein, E5R and Nac1; BMB, 1,4-bismaleimidobutane; BTB, bric-` a-brac, tramtrack and broad complex; FASN, fatty acid synthase; FLAG-Nac1 2 − 514 , ...
9
Therapeutic applications of transcription factor decoy oligonucleotides
... single transcription factor may vary by several base pairs when found in the promoter regions of different genes; in this case, a common motif, or consensus binding site, can be ...different ...
6
Variable structure motifs for transcription factor binding sites
... of transcription factors in vitro. Data for many transcription factors are available in their UniProbe database ...those transcription factors assayed using this ...of transcription ...
20
Variable structure motifs for transcription factor binding sites
... DNA-transcription factor binding sites (TFBSs) have been based on relatively few known instances and have treated them as sites of fixed length using position weight matrices ...some transcription ...
19
Transcription factor mutations as a cause of familial myeloid neoplasms
... ing transcription factors continue to unveil mechanistic insights that may provide new avenues for innovating much-sought-after molecularly targeted ...The transcription factors described herein exhibit ...
14
Activated transcription factor nuclear factor kappa B is present in the atherosclerotic lesion
... Nuclear factor-kappa B (NF- k B)/Rel transcription factors play an important role in the inducible regulation of a vari- ety of genes involved in the inflammatory and proliferative responses of ...this ...
9
Spliced Leader RNA Gene Transcription in Trypanosoma brucei Requires Transcription Factor TFIIH
... gene transcription in Trypanosoma brucei, the general transcription factor (GTF) IIB and a complex, consisting of the TATA-binding protein–related protein 4, the small nuclear RNA-activating protein ...
9
Characterisation of a cellular transcription factor which co-ordinates cell cycle events with transcription
... cellular transcription factors regulated during ...cellular transcription factor PEAl (murine AP-1) which regulates expression of the polyoma enhancer and is abundant in differentiated cells but low ...
305
When is a transcription factor a NAP?
... (the Factor for Inversion Stimula- tion) is viewed as a NAP, it can function as a conventional transcription factor by recruiting RNA polymerase via protein-protein contacts to initiate ...
8
Transcription factor ETV1 is essential for rapid conduction in the heart
... maintaining normal cardiac rhythm and optimal cardiac output. Conduction defects in these tissues produce a disproportionate burden of arrhythmic disease and are major predictors of mortality in heart failure patients. ...
17
Transcription factor MITF regulates cardiac growth and hypertrophy
... High levels of microphthalmia transcription factor (MITF) expression have been described in several cell types, including melanocytes, mast cells, and osteoclasts. MITF plays a pivotal role in the ...
10
Phosphorylation and dimerisation of transcription factor ATF-1
... alian transcription factor CREB is thought to activate cA M P-inducible genes in a variety of differentiated cell types and is probably involved in o th e r sig n a llin g p a th w a y s ...
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