Transcriptional enhancer
Persistence of an Oncogenic Papillomavirus Genome Requires cis Elements from the Viral Transcriptional Enhancer
... in transcriptional regulation and initiation of replication, as well as its assumed role in genome ...the transcriptional enhancer portion of the URR (upstream regulatory region) are required in cis ...
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Genome wide mapping of transcriptional enhancer candidates using DNA and chromatin features in maize
... tional enhancer candidates in maize by comparing DNA and chromatin features in two maize tissues and by providing details on some of their ...1500 enhancer candidates that were characterised by increased ...
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Pointed regulates an eye specific transcriptional enhancer in the Drosophila hedgehog gene, which is required for the movement of the morphogenetic furrow
... together to confer this dual regulation. This is consistent with the model we discussed previously (see Introduction): that special dual regulation of hedgehog is the mechanism which makes the morphogenetic furrow move, ...
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Transcriptional enhancer activity of hr5 requires dual-palindrome half sites that mediate binding of a dimeric form of the baculovirus transregulator IE1.
... hr5 enhancer activity and interaction with AcMNPV ...abolished enhancer activity, a finding consis- tent with required interaction of dimeric IE1 with both 28-mer half ...28-mer enhancer module is a ...
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Rostral hindbrain patterning involves the direct activation of a Krox20 transcriptional enhancer by Hox/Pbx and Meis factors
... wild-type enhancer led to specific lacZ reporter expression in the r3-r5 region in more than half of the transgenic embryos ...the enhancer in r3 and r5 compared with r4 is different in the chick and mouse ...
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Genome wide mapping of transcriptional enhancer candidates using DNA and chromatin features in maize
... tional enhancer candidates in maize by comparing DNA and chromatin features in two maize tissues and by providing details on some of their ...1500 enhancer candidates that were characterised by increased ...
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Transcriptional Enhancer Activity of Biochemically Marked Genomic Elements
... are enhancer elements with previously undefined ...H enhancer element in the olfactory receptor system, together with a small set of similarly biochemically marked function specific enhancers in the genome, ...
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Transcriptional activation of a retrovirus enhancer by CBF (AML1) requires a second factor: evidence for cooperativity with c-Myb.
... Transcriptional enhancer sequences within the long terminal repeats (LTRs) of murine leukemia viruses are the primary genetic determinants of the tissue specificity and potency of the oncogenic potential of ...
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Function of a unique sequence motif in the long terminal repeat of feline leukemia virus isolated from an unusual set of naturally occurring tumors.
... the transcriptional promoter and en- hancer elements necessary for viral gene ...the transcriptional enhancer and immedi- ately adjacent sequences (reviewed in reference ...specific enhancer ...
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The adenovirus E1A 12S product displays functional redundancy in activating the human proliferating cell nuclear antigen promoter.
... Sequences in ElA proteins of human adenovirus 5 required for cell transformation, repression of a transcriptional enhancer, and induction of proliferating cell nuclear antigen.. Inductio[r] ...
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The MADS box transcription factor MEF2C regulates melanocyte development and is a direct transcriptional target and partner of SOX10
... a transcriptional enhancer of Mef2c that directs expression to the neural crest and its derivatives, including melanocytes, in transgenic mouse ...crest enhancer contains three functional SOX binding ...
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Histone deacetylase degradation andMEF2 activation promote the formation of slow twitch myofibers
... pharmacological blockade of proteasome function specifically increases expression of class II HDAC proteins in the soleus in vivo. Using gain- and loss-of-function approaches in mice, we discovered that class II HDAC ...
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Identification of a novel intronic enhancer responsible for the transcriptional regulation of musashi1 in neural stem/progenitor cells
... Next, the secondary neurospheres containing minimal reporter genes were dissociated, and the cells were cul- tured for neuronal and glial differentiation in the same conditions as in the experiment shown in Figure 2A. ...
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Overlapping enhancer/promoter and transcriptional termination signals in the lentiviral long terminal repeat
... of transcriptional readthrough assays show that deletion of NFκB binding sites (U3D) significantly increases the RNA readthrough rate (p < ...the transcriptional termination function. The deletion of all ...
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Evf2 (Dlx6as) lncRNA regulates ultraconserved enhancer methylation and the differential transcriptional control of adjacent genes
... DNA methylation is an epigenetic modification associated with transcriptional changes in plants and animals (Feng et al., 2010; Smith and Meissner, 2013). Although factors involved in DNA methylation have been ...
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Transcriptional activity of avian retroviral long terminal repeats directly correlates with enhancer activity.
... After we had demonstrated that the FSV LTR is intermediate in transcriptional activity between the LTRs of the endogenous and other exogenous avian retroviruses, it was of interest to de[r] ...
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A Strong Negative Transcriptional Regulatory Region between the Human Cytomegalovirus UL127 Gene and the Major Immediate-Early Enhancer
... MIE enhancer and the flanking regions were assigned arbitrary boundaries to better discuss this com- plicated regulatory region (52, ...MIE enhancer between ⫺550 and ⫺50 has cis- acting elements in ...
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Transcriptional activity of core binding factor-alpha (AML1) and beta subunits on murine leukemia virus enhancer cores.
... polyomavirus enhancer-binding protein 2 and SL3 enhancer factor 1, is a mammalian transcription factor that binds to an element termed the core within the enhancers of the murine leukemia virus family of ...
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Functional similarities between human immunodeficiency virus type 1 and simian virus 40 kappa B proto-enhancers.
... Examination of the cell-specific enhancer activity of the individual HIV-1 KB proto-enhancers showed that, like the broadly active SV40 KB proto-enhancer C proto-enhancer, they are all a[r] ...
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The first enhancer in an enhancer chain safeguards subsequent enhancer promoter contacts from a distance
... by specific proteins [22]. Since the cooperative gene regulation by multiple enhancers might be related to multi-way contacts for chromatin loops [19, 23, 24], genome-wide methods such as chromosome walks (C- walks), ...
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