transcriptional repression
Remodeling of O Antigen in Mucoid Pseudomonas aeruginosa via Transcriptional Repression of wzz2
... Remodeling of O Antigen in Mucoid Pseudomonas aeruginosa via Transcriptional Repression of wzz2 Remodeling of O Antigen in Mucoid Pseudomonas aeruginosa via Transcriptional Repression of wzz2 Ashley R[.] ...
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Less is more: specification of the germline by transcriptional repression
... gene-specific transcriptional repression and activation has ...that transcriptional repression and chromatin remodeling are key to germ cell specification in many ...active repression ...
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Brd4-Independent Transcriptional Repression Function of the Papillomavirus E2 Proteins
... E2-dependent transcriptional activation, which is strongly inhibited by the disruption of E2/Brd4 binding as well as by short hairpin RNA (shRNA) knockdown of Brd4 expression ...both transcriptional ...
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Mechanisms of transcriptional repression by histone lysine methylation
... and transcriptional repres- ...mediates repression of E2F regulated promoters (Gray et ...assist transcriptional repression, though, is ...
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Hypoxia and Chromatin, a Focus on Transcriptional Repression Mechanisms
... and repression [12, ...gene repression is likely to be indirectly mediated by HIF probably through trans-acting ...the repression of MYC targets such as PPAR-Gamma Coactivator 1-Beta (PGC-1 β) ...the ...
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NCoR1 Mediates Papillomavirus E8^E2C Transcriptional Repression
... E2C transcriptional repression, we employed a proteomic strategy utilizing the Com- parative Proteomic Analysis Software Suite (CompPASS) to identify interacting cellular proteins for ...
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zif 1 translational repression defines a second, mutually exclusive OMA function in germline transcriptional repression
... 2008). Transcriptional repression in P2, as measured by a lack of Ser2P, requires a high level of PIE-1 protein, and derepression can even be detected in embryos missing one of the two copies of the pie-1 ...
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The adenovirus E1A oncoprotein N-terminal transcriptional repression domain enhances p300 autoacetylation and inhibits histone H3 Lys18 acetylation
... Using conditions of strong H3K18 acetylation when both p300 and Gal4-VP16 were present, we examined the effects of increasing amounts of purified E1A 1-80, and two mutants, C6A and L20A, that are defective in ...
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IE2 protein is insufficient for transcriptional repression of the human cytomegalovirus US3 promoter.
... to transcriptional repression include the US3 proteins, with the US3 proteins functioning in an autoregulatory manner, analo- gous to IE2 repression of the mIE ...mediate transcriptional ...
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Transcriptional repression of specific host genes by the mycovirus Cryphonectria hypovirus 1.
... porter genes. (A) Transcriptional down-regulation. Data are expressed as ratios of the densities of signals after autoradiography of transcripts of the reporter genes from the infected strain (UEP1) compared with ...
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Transcriptional Repression of C4 Complement by Hepatitis C Virus Proteins
... The complement system has been shown to contribute to host protection from virus infection. C4 plays a vital role in mounting an effective immune response. In this study, we have shown a significant reduction of C4 mRNA ...
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Transcriptional repression of FOXO1 by KLF4 contributes to glioma progression
... and transcriptional activation are tightly regulated by multiple posttranslational modifications, including phosphorylation, acetylation, ubiquitination and methylation ...
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EVI1 promotes tumor growth via transcriptional repression of MS4A3
... EVI1 is an oncogene whose overexpression is associated with high aggressiveness of both hematological and solid tumors [1-4,7,9,11,12,15,16]. Even though this correl- ation is well established, and the molecular ...
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Defining the transcriptional and biological response to CDK4/6 inhibition in relation to ER+/HER2- breast cancer
... One of the known features of the response to CDK4/6 inhibitors is the maintenance or accumulation of cyclin D1 expression [30, 31]. This phenomenon was clearly observed in T47D cells; however, this effect on cyclin D1 ...
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Korenjak, Michael (2006): Purification and Characterization of Retinoblastoma like Factor-containing Protein Complexes from Drosophila melanogaster. Dissertation, LMU München: Fakultät für Biologie
... hMip130/TWIT mutant mice do not show any obvious phenotype. However, the simultaneous mutation of hMip130/TWIT and the cell cycle regulatory factor cdk4, whose single inactivation results in decreased cell proliferation ...
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Functional characterization of rare FOXP2 variants in neurodevelopmental disorder
... localization, transcriptional repression, protein dimerization, and interaction with co-repressor proteins, suggesting that all of these variants are benign rare polymorphisms (Table ...
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Nuclear cathepsin D enhances TRPS1 transcriptional repressor function to regulate cell cycle progression and transformation in human breast cancer cells
... Finally, to determine whether Cath-D promotion of TRPS1 transcriptional repression was not confined to PTHrP, the transcriptomes of T47D cells transfected with siRNAs against Cath-D or/a[r] ...
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A garden of Notch ly delights
... of transcriptional repressors interact via a WRPW/YRPW motif with the WD motif of Groucho/Grg/Tle co- repressor proteins (Jennings et ...for transcriptional repression, this structural analysis could ...
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Gene-Environment Interactions and Epigenetic Basis of Human Diseases
... reversible transcriptional repression, which is followed by H3-K9 methylation and promoter DNA methylation to stabilize the silenced chromatin state (Mutskov and Felsenfeld, ...
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Isolation and characterisation of transcribed sequences from human chromosome 9q
... al., 1994), the human homeobox gene EVX1 (Briata et al., 1995), the murine homeodomain gene Msx-1 (Catron et al., 1995) and the human core binding factor alpha-1 subunit, CBFA1 (Acc. No. L40992). These alanine-rich ...
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