Transendothelial migration
Interleukin-1β induces CXCR3-mediated chemotaxis to promote umbilical cord mesenchymal stem cell transendothelial migration
... and migration undergo a series of interactions with endothelial cells (ECs) followed by “transendothelial migration” to enter the target ...lial migration are not well understood. Although MSC ...
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The presence of alpha-catenin in the VE-cadherin complex is required for efficient transendothelial migration of leukocytes
... The majority of the leukocytes cross the endothelial lining of the vessels through cell-cell junctions. The junctional protein Vascular Endothelial (VE)-cadherin is transiently re-distributed from sites of cell-cell ...
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Granulocyte Colony-Stimulating Factor Improves Deficient In Vitro Neutrophil Transendothelial Migration in Patients with Advanced Liver Disease
... and transendothelial migration in 14 cirrhotic patients and 14 healthy ...transendothelial migration. G-CSF enhances neutrophil transendothelial migration in cirrhotic patients ...
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A novel neuregulin – jagged1 paracrine loop in breast cancer transendothelial migration
... hance transendothelial migration of MDA-MB 231 cells, indicating an important role for macrophage JAG1 expres- sion ...of transendothelial migration when placed in an iTEM assay with ...
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Live Brugia malayi microfilariae inhibit transendothelial migration of neutrophils and monocytes.
... In this study we report new insights into the EC response to live B. malayi Mf in their vascular environment, albeit within by the limitations of an ex vivo model which uses an EC isolate under static conditions ...
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Identification of high endothelial cell-derived chemokines that regulate T lymphocyte transendothelial migration
... of transendothelial migration of 80 % of the T lymphocytes by PTX- pretreatment, was due to blockade of chemokine receptor ...directed migration of cells (Sharp et ...the transendothelial ...
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Concise review : MSC adhesion cascade insights into homing and transendothelial migration
... Mesenchymal stem cells (MSCs) are promising candidates for adult cell therapies in regenerative medicine. To fully exert their potential, efficient homing and migration toward lesion sites play an important role. ...
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Recognition of an endothelial determinant for CD 18 dependent human neutrophil adherence and transendothelial migration
... the transendothelial migration induced by 4-h IL- 1 ...and migration as seen with ...and transendothelial migration of PMN in vitro depend substantially on both CD18 on the PMN and ...
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Vascular endothelial cadherin phosphorylation modulates endothelial cell permeability and leukocyte transendothelial migration
... Transendothelial migration involves many complex interactions and signaling pathways between the leukocytes and the endothelial cells that line the lumen of the blood ...during transendothelial ...
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Measles Virus-Induced Block of Transendothelial Migration of T Lymphocytes and Infection-Mediated Virus Spread across Endothelial Cell Barriers
... and migration of T cells. Transendothelial migration beginning with rolling, arrest, adhesion strengthening, and spreading of leukocytes at endothelial surfaces depends on proper signal transduction ...
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VLA 4 integrin can mediate CD11/CD18 independent transendothelial migration of human monocytes
... The migration of human monocytes across unactivated and activated human umbilical vein endothelium (HUVE) in response to chemotactic factors was studied, and the adhesion molecules involved were ...characterized. ...
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Phenotypic characteristics of human monocytes undergoing transendothelial migration
... preferential migration of a particular subset of monocytes or as a result of the interaction of monocytes with the ...preferential migration of a particular subset, we would have expected a depletion of ...
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Potential role of CXCL9 induced by endothelial cells/CD133+ liver cancer cells co-culture system in tumor transendothelial migration
... Hepatocellular carcinoma (HCC) is the fifth most common cancer and the second leading cause of cancer- associated deaths, which is over 600,000 around the world [1]. The poor prognosis with overall survival rates of 3-5% ...
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Novel roles for ICAM1 in leukocyte transendothelial migration
... Inflammation occurs in response to diverse types of tissue injury and is required for numerous physiologic and pathologic processes. One of the key regulated steps in inflammation is transmigration of leukocytes across ...
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Multiomics analyses identified epigenetic modulation of the S100A gene family in Kawasaki disease and their significant involvement in neutrophil transendothelial migration
... leukocyte migration, neutrophil migration, and neutrophil chemotaxis (Additional file ...lial migration, which is the causes of vascular inflam- mation and coronary artery aneurysm ...leukocyte ...
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Interleukin 15 is produced by endothelial cells and increases the transendothelial migration of T cells In vitro and in the SCID mouse human rheumatoid arthritis model In vivo
... hances transendothelial migration of all T cell subsets with some bias toward CD8( 1 ) T ...the migration of both CD4( 1 ) and CD8( 1 ) T cells is significantly enhanced by ...increase ...
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Transendothelial migration of human umbilical mesenchymal stem cells across uterine endothelial monolayers: junctional dynamics and putative mechanisms
... Abbreviations: Mesenchymal stem cells MSC from Wharton’s jelly of human umbilical cords WJ-MSC, human uterine microvascular endothelial cells HUtMEC, vascular endothelial cadherin VE-cad[r] ...
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Cooperative interactions of LFA 1 and Mac 1 with intercellular adhesion molecule 1 in facilitating adherence and transendothelial migration of human neutrophils in vitro
... Supporting evidence is found in the effects of monoclonal antibodies on adhesion to HUVEC monolayers in vitro: a Unstimulated PMN adhere to HUVEC monolayers stimulated for 18 h with IL- [r] ...
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Emerging role of LOXL2 in the promotion of pancreas cancer metastasis
... Lysyl oxidase-like 2 (LOXL2) is associated with invasiveness and metastasis in cancer. We analyzed the prognostic impact of LOXL2 in pancreatic cancer patients and investigated the role of LOXL2 in pancreatic cancer cell ...
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Khandoga, Alexander (2009): Mechanisms of leukocyte transendothelial and interstitial migration during inflammation in vivo. Dissertation, LMU München: Medizinische Fakultät
... leukocyte transendothelial migration are described in the literature: i) the transcellular route, when leukocytes emigrate through the body of endothelial cells, and ii) the paracellular route, when ...
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