transfer hydrogenation
Imino transfer hydrogenation reductions
... the transfer hydrogenation of C=N bonds, including asymmetric versions, because this has been reported adequately in a range of other ...for transfer hydrogenation (TH) and asymmetric ...
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The Nature of the True Catalyst in Transfer Hydrogenation with Alcohol Donors Using (arene)2Ru2Cl4(II)/TsDPEN Precursor
... asymmetric transfer hydrogenation (ATH) reactions with 2-propanol as hydrogen donor at ambient conditions, is proven to be unstable under the strong reducing conditions prevailing in the reaction mixtures ...
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The Application of New Chiral Ferrocene Ligands in Asymmetric Transfer Hydrogenation of Ketones
... DOI: 10.4236/ijoc.2018.81004 59 International Journal of Organic Chemistry [2] Seo, Y.J., Kim, J.A. and Lee, H.K. (2015) Stereoselective Synthesis of 4-Substituted Cyclic Sulfamidate-5-Phosphonates by Using Rh-Catalyzed, ...
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Asymmetric Transfer Hydrogenation in Water with Platinum Group Metal Catalysts3-19
... asymmetric transfer hydrogenation (ATH) has emerged as a powerful and practical tool for reduction reactions in both academia and indus- try, due to its operational simplicity, high reaction rate and ...
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From transfer hydrogenation to transamination: new methods for the preparation of N-Heterocycles
... equipment, transfer hydrogenation (TH) offers an alternative by using isopropanol (IPA) or formate ...either hydrogenation or TH, there appears to be no single catalyst capable of reducing all three ...
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Easy to synthesize, robust organo osmium asymmetric transfer hydrogenation catalysts
... [1] Reviews on asymmetric transfer hydrogenation; a) R. Noyori, S. Hashigu- chi, Acc. Chem. Res. 1997, 30, 97– 102; b) S. E. Clapham, A. Hadzovic, R. H. Morris, Coord. Chem. Rev. 2004, 248, 2201 –2237; c) ...
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Transfer hydrogenation catalysis in cells as a new approach to anticancer drug design
... (0.5, 1 and 2 mM). The antiproliferative activity of complexes 1–7 was enhanced by co-administration with formate (Supplementary Tables 7 and 8; Fig. 2). The degree of enhancement of activity was directly proportional to ...
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Asymmetric transfer hydrogenation reductions using tethered ruthenium (II) catalysts
... Transfer hydrogenation or hydrogen-transfer is the reduction of multiple bonds with the use of a hydrogen donor in the presence of a catalyst (Scheme ...of transfer hydrogenation as ...
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Transfer hydrogenation and antiproliferative activity of tethered half sandwich organoruthenium catalysts
... coadministration with nontoxic concentrations of sodium formate (0.5 − 2 mM). Complex 2 binds to nucleobase guanine (9- EtG), but DNA appears not to be the target, as little binding to calf thymus DNA or bacterial ...
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Use of triazole ring formation to attach a Ru/TsDPEN complex for asymmetric transfer hydrogenation to a soluble polymer
... Abstract—The cycloaddition of a chiral ligand containing a terminal alkyne to a soluble polymer containing an azide provides a convenient means for the attachment of an asymmetric transfer hydrogenation ...
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Computational studies explain the importance of two different substituents on the chelating bis(amido) ligand for transfer hydrogenation by bifunctional Cp*Rh(III) catalysts
... a transfer hydrogenation process proceeding by an outer-sphere mechanism, H + and H – are transferred from one species to ...hydrogen transfer from formic acid to a Rh – NX bond in different Rh III ...
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The importance of the N–H bond in Ru/TsDPEN complexes for asymmetric transfer hydrogenation of ketones and imines
... Soni, Rina, Cheung, Fung Kei, Clarkson, Guy J., Martins, Jose E. D., Graham, Mark A. and Wills, Martin. (2011) The importance of the N–H bond in Ru/TsDPEN complexes for asymmetric transfer hydrogenation of ...
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Half sandwich rhodium(III) transfer hydrogenation catalysts : reduction of NAD+ and pyruvate, and antiproliferative activity
... Transfer hydrogenation reactions for the reduction of ketones, imines or C _ C double bonds have been intensively studied in recent years [1 – ...as transfer hydrogenation catalysts, and ...
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Application of ruthenium complexes of triazole containing tridentate ligands to asymmetric transfer hydrogenation of ketones
... (3) (a) Wills, M. in Modern Reduction Methods, ed. Andersson, P. G.; Munslow, I. J. Wiley-VCH, Weinheim, 2008, Chapter 11, pp 271- 296. (b) Uematsu, U.; Fujii, A.; Hashiguchi, S.; Ikariya, T.; Noyori, R. J. Am. Chem. ...
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Ether tethered Ru(ii)/TsDPEN complexes : synthesis and applications to asymmetric transfer hydrogenation
... diamine ligand with a Ru(II) arene unit. 2-7 These catalysts may be employed in both asymmetric transfer hydrogenation (ATH) 3 reactions, i.e. using an organic compound as the hydrogen source, or direct ...
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The contrasting catalytic efficiency and cancer cell antiproliferative activity of stereoselective organoruthenium transfer hydrogenation catalysts
... ‘Tethered’ complexes such {N-[(1R,2R)-1,2-diphenylethyl-2-(3- phenylpropylamino)]-4-methylbenzenesulfonamide}ruthenium chloride (Scheme 2, compound 7) are known to be particularly effective catalysts, capable of ...
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Effect of sulfonamidoethylenediamine substituents in RuII arene anticancer catalysts on transfer hydrogenation of coenzyme NAD+ by formate
... of transfer hydrogenation of coenzyme NAD + with formate as hydride donor as determined by NMR and UV-vis spec- ...faster hydrogenation rates (Table ...hydride transfer form formate to NAD + ...
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Recent developments in the area of asymmetric transfer hydrogenation
... In order to test this we examined the transfer hydrogenation of a 1:1 mixture of propiophenone (which is known to be a good substrate) and α-methoxyacetophenone. In the event neither ketone was reduced, ...
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Solvent Selection in Transfer Hydrogenation and Suzuki Cross coupling
... As product separation and catalyst and solvent recycling also determine the sustainability of a reaction process, these parameters were also considered for the transfer hydrogenation reaction. In the case ...
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Low Temperature Catalytic-Transfer Hydrogenation of Candlenut Oil
... (direct hydrogenation) at relatively high temperature and pressure with the aid of nickel as a catalyst, which prone to explosion due to the presence of free gaseous hydrogen at high temperature and ...Catalytic ...
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