Transient Receptor Potential Channels
The role of transient receptor potential polycystin channels in bone diseases
... via channels is highly significant for various physiological cellular and tissue ...druggable channels, which are called transient-receptor potential ...
13
The role of Transient Receptor Potential (TRP) channels in the pathogenesis of COPD
... TRP Channels Transient Receptor Potential channels are a superfamily of cation channels, of which there are 28 known mammalian members (Banner et ...1 channels include ...
218
Redox-sensitive transient receptor potential channels in oxygen sensing and adaptation
... of transient receptor potential (TRP) cation- permeable channels, which have exquisite sensitivity to redox reactive ...TRP channels, the TRPA1 channel has emerged as a sensor in non-CB ...
14
Polymodal roles of transient receptor potential channels in the control of ocular function
... aberrant transient rather than sustained retinal membrane depolarization ...capsaicin receptor since this red pepper extract con- stituent is an agonist of this ...mechano- potential); f ) TRPP ...
10
Temperature-Sensitive Transient Receptor Potential Channels in Corneal Tissue Layers and Cells
... maxi-K channels or small conductance calci- um-activated potassium channels results in an increased Ca 2+ influx [12] ...a potential drug target for improving the outcome of in- flammatory/fibrogenic ...
10
Transient receptor potential (TRP) channels in human colorectal cancer: evidence and perspectives
... TRPM channels in cell ...of transient receptor potential channels in peripheral blood mononuclear cells of inflammatory bowel disease ...
12
Original Article Role of transient receptor potential channels in airway smooth muscle cell growth
... Department of Respiratory Medicine, People’s Hospital Affiliated to Zhengzhou University, Zhengzhou, China Received October 10, 2016; Accepted November 25, 2016; Epub March 1, 2017; Published March 15, 2017 Abstract: The ...
9
The Role of Transient Receptor Potential (TRP) Channels in the Transduction of Dental Pain
... ion channels and receptors localized in the dental primary afferent neurons (DPAs) and odontoblasts have been implicated in the transduction of dental pain, and functional expression of various polymodal ...
31
Transient receptor potential (TRP) channels as drug targets for diseases of the digestive system
... mammalian transient receptor potential (TRP) channel subunits are expressed by specific neurons and cells within the alimentary ...TRP channels operate either as primary detectors of chemical ...
29
Expression of transient receptor potential vanilloid (TRPV) channels in different passages of articular chondrocytes
... of transient receptor potential vanilloid channel members 4, 5 and 6 (TRPV4, TRPV5 and TRPV6) in equine articular ...these channels in serially passaged articular ...
13
Transient Receptor Potential Ion Channels in the Etiology and Pathomechanism of Chronic Fatigue Syndrome/Myalgic Encephalomyelitis
... of transient receptor potential (TRP) ion channels in neurological and metabolic systems in CFS/ME patients possibly contributing to the clinical expression of the ...the potential role ...
9
Transient receptor potential melastatin 2 channels are overexpressed in myalgic encephalomyelitis/chronic fatigue syndrome patients
... Cassandra Balinas 1,2* , Helene Cabanas 1,2 , Donald Staines 1,2 and Sonya Marshall‑Gradisnik 1,2 Abstract Background: Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is hallmarked by a significant reduction ...
11
Overexpression of transient receptor potential mucolipin-2 ion channels in gliomas: role in tumor growth and progression
... of transient receptor potential mucolipin-2 ion channels in gliomas: role in tumor growth and progression Maria Beatrice Morelli 1,2 , Massimo Nabissi 1 , Consuelo Amantini 3 , Daniele ...
15
Heat Avoidance Is Regulated by Transient Receptor Potential (TRP) Channels and a Neuropeptide Signaling Pathway in Caenorhabditis elegans
... of transient receptor potential (TRP) channels is heat activated and proposed to be responsible for heat detection in vertebrates and fruit ...neuropeptide receptor gene ...NPR-1 ...
23
Structural Analyses of the Transient Receptor Potential Channels TRPV3 and TRPV6
... 19 (OH)2D3), the activated form of vitamin D 80 . 1,25-(OH)2D3 binds the vitamin D receptor in the epithelial cells of the intestine and results in the transcription of TRPV6 71,81-84 . To better understand the ...
132
Original Article Changes of stretch-activated channel-transient receptor potential channels in atrial myocardium of rabbits with heart failure
... TRP channels are a group of cationic ion chan- nels located on the plasma membrane. TRPC1 was the first TRP channel identified in mamma- lian tissue, which is now known to be widely dis- tributed among various ...
6
Different contribution of redox-sensitive transient receptor potential channels to acetaminophen-induced death of human hepatoma cell line
... TRP channels expressed in human hepatoma cell line (HepG2), serving as a model of human liver hepatocytes, and to investigate the roles of these channels in APAP-induced oxidative stress, Ca 2+ influx and ...
22
The transient receptor potential family of ion channels
... TRP channels. (a) All channels contain six transmembrane segments (S1 to S6) with a putative pore region (P) between S5 and ...TRP channels and are only partially preserved within members of the same ...
11
Transient Receptor Potential (TRP) Channels and Cardiac Fibrosis
... fibroblast proliferation and differentiation. Inhibition of TRPC3 suppressed extracellular- signal regulated kinase (ERK)-phosphorylation, resulting in reduced fibroblast proliferation. The Ca 2+ mediated fibroblast ...
25
Transient receptor potential (TRP) gene superfamily encoding cation channels
... Conclusions Activation of TRP channels in the eye elicits responses needed for ocular sensory and cellular functions. In mammals, TRP channel subunit pro- teins are encoded by 27 genes and are grouped into six ...
9