translation initiation factors
Foot-and-Mouth Disease Virus 3C Protease Induces Cleavage of Translation Initiation Factors eIF4A and eIF4G within Infected Cells
... This is the first report that the FMDV 3C protease induces the cleavage of cellular translation initiation factors. The evidence from the transient-expression assays showed that FMDV 3C is able to ...
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Recent insights into eukaryotic translation initiation factors 5A1 and 5A2 and their roles in human health and disease
... eukaryotic translation initiation factors were sug- gested as a host cell cofactor for viruses replication and propagation, including ...RNA translation and cap-dependent RNA ...
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VPg of murine norovirus binds translation initiation factors in infected cells
... tion of mRNAs that have different eIF requirements for functional initiation complex assembly [5]. All of these data were obtained using purified protein and cell-free assays. Human noroviruses do not grow in cell ...
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Picornavirus Internal Ribosome Entry Site Elements Target RNA Cleavage Events Induced by the Herpes Simplex Virus Virion Host Shutoff Protein
... ongoing translation to be targeted by vhs (59, ...for initiation factors that function to recruit ribosomes to the ...with translation initiation factors predicts that the 5⬘ cap ...
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Global mRNA selection mechanisms for translation initiation
... between translation initiation factors [12] such that, in the steady state, eIF4G exists in the eIF4F complex with ...various translation initiation factors associated with the ...
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Sumoylation of eIF4A2 affects stress granule formation
... of translation, with many translation initiation factors, ribosomal subunits and mRNAs being sequestered into stress granules or P ...the translation machinery. Many aspects of ...
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Genome-wide microRNA changes in human intracranial aneurysms
... protein translation machinery, including various eukaryotic translation initiation factors and ribosomal proteins, and this finding was highly correlated with our previous transcriptome data ...
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RNA Degradation in Saccharomyces cerevisae
... in translation initiation increase the pool of mRNAs in P-bodies (Teixeira et ...to translation (Brengues et ...with translation initation factors and RNA-binding proteins (reviewed in ...
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Ribosomal RACK1 promotes chemoresistance and growth in human hepatocellular carcinoma
... selective translation of specific mRNAs that promote tumor survival and growth (6, ...tion initiation factors, which contribute to aberrant translational control, have been reported in a wide range ...
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Impaired Binding of Standard Initiation Factors Mediates Poliovirus Translation Attenuation
... these translation initiation factors and hence impair the association of the ribo- some with the viral ...reduced translation efficiencies of these con- structs ...these factors and not ...
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<p>eIF2α promotes vascular remodeling via autophagy in monocrotaline-induced pulmonary arterial hypertension rats</p>
... that translation initiation factors play a key role in regulating certain functional proteins to promote cell ...tic initiation factor 2 α (eIF2 α ) plays a key role in regulat- ing cell ...
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Experimental Analysis of Mimivirus Translation Initiation Factor 4a Reveals Its Importance in Viral Protein Translation during Infection of Acanthamoeba polyphaga
... to translation in its genome is highly intriguing as their biological importance remains unknown (18, ...protein factors involved in translation, along with aa-RSs and tRNAs, contradicted the dogma ...
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Interaction of eukaryotic initiation factor eIF-4B with a picornavirus internal translation initiation site.
... otides into the region of stem-loop 5 could indicate that the interaction site is localized near the 39 end of the IRES, pos- sibly including the translational start codon. Deletion of stem- loop 4 also interferes with ...
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The Biological Roles of Translation Initiation Factor 3b
... eIF3b-mediated translation for tumor treatment, particularly via the phosphorylation of the eIF3 complex at seven phosphorylation sites (Ser-83, Ser-85, Ser-119, Ser-125, Ser-152, Ser-154, and Ser-164) and one ...
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Efficient Translation of Rotavirus mRNA Requires Simultaneous Interaction of NSP3 with the Eukaryotic Translation Initiation Factor eIF4G and the mRNA 3′ End
... eukaryotic initiation factor eIF4G (14, 23, ...first initiation codon ...the translation of the mRNA by allowing rapid reinitiation of new rounds of ...accurate initiation when competition ...
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Taking aim at translation for tumor therapy
... mRNA translation rates are frequently observed in human ...eukaryotic translation initiation factor 4E (eIF4E), leading to enhanced translation of numerous tumor-promoting ...
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The internal initiation of translation in bovine viral diarrhea virus RNA depends on the presence of an RNA pseudoknot upstream of the initiation codon
... Relative translation efficiency of SEAP and luciferase reporter genes of the respective dicistronic or monocistronic plasmids in stably transfected BHK ...of translation efficiency when the effects of ...
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Alternative Translation Initiation of Theiler’s Murine Encephalomyelitis Virus
... on translation initiation in FMDV. FMDV translation naturally occurs at two in-frame AUGs separated by 84-nt, with usage varying among different viral isolates; the two AUGs encode either a full- ...
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Translational control of protein synthesis after infection by vesicular stomatitis virus.
... Infection does result in a reduction in the rate of initiation of translation of all predominant species of cellular mRNA, but translation of cellular and viral mRNA's which encode for t[r] ...
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Avian Reovirus Nonstructural Protein p17-Induced G2/M Cell Cycle Arrest and Host Cellular Protein Translation Shutoff Involve Activation of p53-Dependent Pathways
... tion phase (S phase) and the nuclear division and cell division phase (M phase), separated by two gap periods (G 1 and G 2 ) (44). Cells progress through each of these phases in a tightly regulated and highly ...
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