transmembrane domains
The Transmembrane Domains of Sindbis Virus Envelope Glycoproteins Induce Cell Death
... E2 transmembrane domain and the minimal E3 signal sequence fused to the E1 transmembrane domain induced death as efficiently as full-length P62 and 6K plus E1, whereas no cell death was observed after ...
9
Structural mutants of dengue virus 2 transmembrane domains exhibit host range phenotype
... brane-spanning domains (transmembrane domains; TMD) of proteins integrated into insect cell membranes have evolved to accommodate both host ...shorter transmembrane domains of viruses ...
15
An NMR study into the structure and interactions of the transmembrane domains of Neu and PDGFβ receptor tyrosine kinases
... induce transmembrane rota- tions in reverse direction to those of ‘outside-in’ signalling (Maruyama, ...the transmembrane domains of these receptors, which have been particularly challenging for ...
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Bipartite Inhibition of Drosophila Epidermal Growth Factor Receptor by the Extracellular and Transmembrane Domains of Kekkon1
... single transmembrane proteins consisting of an extracellular domain composed of seven LRRs and a single Ig ...and transmembrane domains of Kek1 are unique in their ability to inhibit EGFR among Kek ...
16
Role of the Transmembrane Domains of prM and E Proteins in the Formation of Yellow Fever Virus Envelope
... TM domains of the envelope proteins of all of the members of the Flaviviridae family ...TM domains of prM and E are in favor of the C termini of prM and E crossing the membrane ...TM domains of prM ...
8
Coordinated Movement of Cytoplasmic and Transmembrane Domains of RyR1 upon Gating
... sensing domains using a plethora of structural arrangements to respond to a variety of effectors (voltage, ion concentration, pH, redox state, small molecules, and ...
16
Transmembrane Domains of Hepatitis C Virus Envelope Glycoproteins: Residues Involved in E1E2 Heterodimerization and Involvement of These Domains in Virus Entry
... TM domains of fusion proteins are essential for their fusion ...TM domains of other fusion pro- teins led to a loss of fusion activity (8, 40, 45, ...TM domains of some fusion proteins have been ...
10
Deletion of DNA encoding the first five transmembrane domains of Epstein-Barr virus latent membrane proteins 2A and 2B.
... The last seven transmembrane and carboxy-terminal cytoplasmic domains of Epstein-Barr virus latent membrane 2 LMP2 are dispensable for lymphocyte infection and growth transformation in v[r] ...
7
Charged Residues in the Transmembrane Domains of Hepatitis C Virus Glycoproteins Play a Major Role in the Processing, Subcellular Localization, and Assembly of These Envelope Proteins
... the transmembrane domain (TMD) is more than just an anchor to the ...anchor domains are composed of two stretches of hydrophobic residues separated by a short segment containing at least one fully conserved ...
11
Transmembrane Domains of Highly Pathogenic Viral Fusion Proteins Exhibit Trimeric Association In Vitro
... M embrane fusion is a critical event in the life cycle of enveloped viruses. Fusion of the viral envelope with the target cell membrane is mediated by the viral fusion protein. The trimeric fusion protein undergoes a ...
6
Investigating helix helix interactions in the transmembrane domains of membrane proteins
... Self-association was monitored using the GALLEX system as described in the text (a) Amino acid sequence of the Ii TM domain insert cloned into the plasmid pBLM100 and subsequently transformed into E.coli strain SU101 as ...
191
Influence of transmembrane domains on the fusogenic abilities of human and murine leukemia retrovirus envelopes.
... these domains is required for the precursor to proceed to the Golgi ...cytoplasmic domains, had no detectable effect on cell surface expression and cell fusion in our ...
9
Assembly of a Functional HCV Glycoprotein Heterodimer
... I transmembrane proteins with a highly glycosylated N-terminal ectodomain and a C-terminal hydrophobic ...The transmembrane domains of HCV envelope glycoproteins play a major role in E1E2 heterodimer ...
17
Activation of Lymphocyte Signaling by the R1 Protein of Rhesus Monkey Rhadinovirus
... Construction of CD8 ⌬ -R1 chimeras. The full-length R1 cy- toplasmic domain (R1C) and deletion mutants derived from it were fused to the extracellular and transmembrane domains of CD8 in order to analyze ...
10
Bacterial polysaccharide synthesis and export
... the transmembrane domains in ...periplasmic domains of various Wzz homologues have been solved [29] as well as the structure of full length Escherichia coli WzzE to a resolution of 6 A ˚ , with all ...
8
Search | Preprints
... single-pass transmembrane protein, which consists of an extracellular ligand-binding domain and an intracellular kinase domain separated by a single transmembrane ...kinase domains into close ...
24
Sperm plasma membrane breakdown during Drosophila fertilization requires Sneaky, an acrosomal membrane protein
... BLAST searches (blastp) (Altschul et al., 1997) of non-redundant sequences in NCBI identified a series of Snky-related proteins present in invertebrates and vertebrates. Of these, a set of proteins, which we refer to as ...
9
LAT1 (SLC7A5) and CD98hc (SLC3A2) complex dynamics revealed by single-particle cryo-EM
... the transmembrane domains of the complex were docked into each volume of the three series, allowing modelling of the flexibility described by their principal components in molecular ...
11
Microdomain formation is a general property of bacterial membrane proteins and induces heterogeneity of diffusion patterns
... analyzed transmembrane proteins did not correlate with protein molecular weight, but correlated inversely with the number of transmembrane helices, ...of transmembrane domains, following the ...
17
The role of the G protein and cAMP/PKA signalling pathway in establishment and maintenance of the mutualistic Epichloë festucae ryegrass association : a thesis presented in partial fulfilment of the requirements for the degree of Doctor of Philosophy in Genetics at Massey University, Palmerston North, New Zealand
... The predicted Pth11-18 polypeptide is 513 amino acids in length and is predicted to contain seven transmembrane domains TM and a GPCR atypical reverse orientation with long intracellular[r] ...
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