TRIALS FOR HYPOFRACTIONATED RADIOTHERAPY:
<p>Moderate hypofractionated radiotherapy vs conventional fractionated radiotherapy in localized prostate cancer: a systemic review and meta-analysis from Phase III randomized trials</p>
... Dovepress Yin et al in the control group, namely in C-RT, are various, ranging from 74 to 80 Gy. Therefore, it is difficult to ascertain which group would benefit most from hypofractionation. Third, the follow-up ...
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Hypofractionated radiotherapy for prostate cancer
... a hypofractionated (55 Gy/20 fractions/4 weeks) ...the hypofractionated group than in the conventionally fractionated group, but not overall ...of hypofractionated compared to conventionally ...
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The Role of Hypofractionated Radiotherapy in Prostate Cancer.
... The outcome of HYPRO [20, 21, 22•] is in keeping with other superiority hypofractionation trials, which did not dem- onstrate an improvement in efficacy outcomes with hypofractionation. Assuming α/β ratio of 1.5 ...
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Precise hypofractionated radiotherapy of moving tumors
... Precise Radiotherapy of hypo-fractionated treatments of moving tumors applied by a linear accelerator was the topic of this PhD ...thesis. Hypofractionated radiotherapy is currently an area of ...
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Toxicity of Hypofractionated Radiotherapy Following Breast Conservative Surgery in Breast Cancer
... after radiotherapy is usually due to an underlying fibrosis, but in the early years, the fat necrosis and breast edema can contribute to induration ...the hypofractionated trials varied from ...
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Treatment of Breast and Prostate Cancer by Hypofractionated Radiotherapy: Potential Risks and Benefits
... hypofractionation trials yielded low a / b ratios on comparing tumour control rates obtained with external beam radiotherapy and low dose rate brachytherapy [26,27] ...these trials are limited in ...
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Definitive hypofractionated radiotherapy for early glottic carcinoma: experience of 55Gy in 20 fractions
... Discussion Dose fractionation along with overall treatment time are expected to be key factors in the outcomes of definitive radiotherapy for early glottis cancer. Schedules with shortened overall treatment times ...
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Role of 3D Hypofractionated Radiotherapy in Treatment of High Grade Gliomas: A Prospective Study
... (3). Radiotherapy has been the most effective treatment for these aggressive lesions, but generally RT can only delay disease progression or recurrence ...prospective trials have shown that hypo ...
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Hypofractionated radiotherapy for the treatment of early breast cancer: a systematic review. November 2011
... Loco-regional recurrence In the Canadian trial study reported in the SIGN guideline, no significant difference in local recurrence free rate at the five-year follow-up was seen (96.8% with 25 fractions vs 97.2% with 16 ...
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Split-course hypofractionated radiotherapy for palliation of advanced head and neck squamous cell carcinoma.
... 23 performance status, age, willingness of patient to undergo aggressive toxic treatment and many other factors come into play. Young patients with good performance status and very advanced lesions can be taken up for ...
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The Effect of Hypofractionated Radiotherapy on Tumor Control and Survival in Patients with High Risk Breast Cancer
... compare hypofractionated radiotherapy and conventional radiotherapy several clinical trials have been ...that hypofractionated radiotherapy was of benefit in early stage breast ...
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Hypofractionated radiotherapy after conservative surgery for breast cancer: analysis of acute and late toxicity
... many trials showed that shorter fractionation schedules are as effective as the conventional schedule of 50 Gy in 25 fractions in terms of preventing recurrence of cancer in the breast ...
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Hypofractionated radiotherapy for breast cancer acceleration of the START A treatment regime: intermediate tolerance and efficacy
... accelerated hypofractionated radiotherapy (RT) in breast cancer patients treated with ...other trials. Conclusion The applied hypofractionated RT regime with single doses of ...
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Review Article Meta-analysis of hypofractionated radiotherapy versus conventional radiotherapy in locally advanced non-small-cell lung cancer
... Some limitations in this meta-analysis should be considered. First, most of the included trials had relatively small sample sizes that made the results lack robust statistical power. Small tri- als may more easily ...
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Radiotherapy in Post Mastectomy High Risk Breast Cancer: Early results of a Prospective Study comparing Conventional versus Hypofractionated Radiotherapy
... with radiotherapy playing an important ...4 trials have shown that addition of loco- regional RT in breast cancer patients significantly decreased the probability of local recurrence ...
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Bevacizumab plus hypofractionated radiotherapy versus radiotherapy alone in elderly patients with glioblastoma: the randomized, open-label, phase II ARTE trial
... clinical trials, but early reports suggested preferential benefit in this ...of hypofractionated RT (40 Gy in 15 fractions) with bevacizumab (10 mg/kg×14 days) (arm A, N = 50) or without bevacizumab (arm B, ...
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To Study Palliation of Symptoms by a Hypofractionated Radiotherapy Schedule in Inoperable Squamous Cell Cancers of the Oral Cavity
... of Radiotherapy or chemoradiotherapy in adjuvant setting Adjuvant therapy with radiation alone or chemoradiation is based on results of histopathological examination of the surgical ...RTOG trials absolute ...
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Economic evaluation and assessment of early toxicity of hypofractionated radiotherapy compared to standard fractionation in breast cancer.
... 3.9 EXTREME HYPOFRACTIONATION: The encouraging results of the previously described hypofractionated radiotherapy trials, inspired people to experiment with further hypofractionation regimens. The UK ...
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Comparison of the dose escalation potential for two hypofractionated radiotherapy regimens for locally advanced pancreatic cancer
... regimens. The constraints are not BED equivalent (/β =3 for GI OAR) but were based on currently recruiting trial protocols [20,21]. It is acknowledged that there is some uncertainty over the true tolerances of GI OAR ...
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Concomitant intensity modulated boost during whole breast hypofractionated radiotherapy – A feasibility and toxicity study
... Mounting evidence supports the theory that breast cancer cells are in fact more sensitive than most other tumors to the effects of fraction size, with a low a /b ratio of 4 Gy, similar to that of late reacting normal ...
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