tricarboxylic acid (TCA) cycle
Structural Basis for the Interaction of 14 3 3β with Tricarboxylic Acid Cycle Intermediate Malate
... Tricarboxylic Acid Cycle intermediate malate was reported in a shuttle between mitochondrion and cytosol, resulting a far more effective pathway in producing NADPH in the cytosol than the pentose ...
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An inherited defect affecting the tricarboxylic acid cycle in a patient with congenital lactic acidosis
... hydratase appeared normal. The binding of citrate to aconitate hydratase and the activities of the NAD- and NADP-linked isocitrate dehydrogenases were also normal, while the activity of citrate synthase was slightly ...
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A Dysfunctional Tricarboxylic Acid Cycle Enhances Fitness of Staphylococcus epidermidis During β Lactam Stress
... TCA cycle (ci- trate synthase, isocitrate dehydrogenase, and aconitase), was con- structed by phage 71 ( ⌽ 71)-mediated transduction of the ⌬ citCZ:: ermB allele into the ...TCA cycle intermediates ...
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Analysis of organic acids of tricarboxylic acid cycle in plants using GC-MS, and system modeling
... 3rd cycle (when the first formation of fumaric acid would occur) to the 12th cycle, was used to estimate the rate transfer coefficients of the difference equations (Table ...succinic acid, ...
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Kinetic modeling of tricarboxylic acid cycle and glyoxylate bypass in Mycobacterium tuberculosis, and its application to assessment of drug targets
... the tricarboxylic acid (TCA) cycle and glyoxylate bypass, isocitrate dehydrogenase (ICD), involved in the TCA cycle, and ICL, involved in the glyox- ylate bypass, compete for the same ...
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Genetic and Biochemical Interactions Involving Tricarboxylic Acid Cycle (TCA) Function Using a Collection of Mutants Defective in All TCA Cycle Genes
... TCA cycle suggesting that NAD-IDH mtRNA binding plays a subtle enzymes, it is possible that they may encode functions role in mitochondrial ...TCA cycle func- clear how defects in another TCA cycle ...
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Tricarboxylic acid cycle enzymes and bicarbonate fixation in morphogenesis of Blastocladiella emersonii.
... plants. These results were considered as evidence in support of the hypothesis that bicarbonate first reversed the flow then induced multiple enzymatic lesions in the TCA cycle. Our results on mature plants ...
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Rational modification of tricarboxylic acid cycle for improving l-lysine production in Corynebacterium glutamicum
... xylic acid (TCA) cycle, which provides several metabolic precursors and cofactors for cell growth and amino acids production ...TCA cycle, such as phos- phoenolpyruvate (PEP)-pyruvate-oxaloacetate ...
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Metabolic engineering of Bacillus amyloliquefaciens for enhanced production of S-adenosylmethionine by coupling of an engineered S-adenosylmethionine pathway and the tricarboxylic acid cycle
... TCA cycle and cell ...TCA cycle and the lysine synthesis pathway, leading to a ...TCA cycle and cell growth in ...TCA cycle and cell growth after deletion of sucC from ...TCA cycle to ...
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Stochastic Variation in Expression of the Tricarboxylic Acid Cycle Produces Persister Cells
... TCA cycle enzymes and in late, gudB (glutamate dehydrogenase), sucA (2-oxoglutarate dehydrogenase), sucC (succinyl-coenzyme A [CoA] synthetase), fumC (fumarate hydratase) TCA cycle enzymes by transducing ...
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Blocks in Tricarboxylic Acid Cycle of Salmonella enterica Cause Global Perturbation of Carbon Storage, Motility, and Host-Pathogen Interaction
... Subsequently, we performed quantitative comparative proteomics and metabolo- mics of S. Typhimurium ΔfumABC ΔglgA and compared the obtained profiles with those of S. Typhimurium ΔfumABC (Fig. 4 and Tables S1 and S3). ...
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Genetic Evidence for Two Carbon Fixation Pathways (the Calvin-Benson-Bassham Cycle and the Reverse Tricarboxylic Acid Cycle) in Symbiotic and Free-Living Bacteria
... reverse tricarboxylic acid (rTCA) cycle and the recently discovered reversed oxidative TCA cycle (roTCA) (1, 3, ...CBB cycle in the symbionts and the large sulfur bacteria is ...
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THE EXCRETION OF l MALIC ACID IN RELATION TO THE TRICARBOXYLIC ACID CYCLE IN THE KIDNEY
... These observations on the several mechanisms of malic acid excretion in the kidney raise several important points about the nature of the phenomena themselves and their relation to the l[r] ...
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Development and Characterization of a Condensed Reverse Tricarboxylic Acid Cycle for Use in Plants.
... amino acid metabolism, lipid metabolism, and a number of other metabolic processes, as well as activating ferredoxin-thioredoxin reductase (FTR) which has an important regulatory role for the CBB cycle and ...
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Role of granulocyte oxygen products in damage of Schistosoma mansoni eggs in vitro
... attachment to eggs resulted in release of O2- (0.30-0.52 nmol/min per 2 X 10(6) cells) and accumulation of H2O2 (0.14-0.15 nmol/min) in the presence of antibody or complement. Granulocytes reduced egg ...
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Complete genome sequence of Hydrogenobacter thermophilus type strain (TK-6T)
... cient hydrogen-oxidizing ability of this strain, which results in a faster generation time com- pared to other autotrophs. It is also able to grow anaerobically using nitrate as an electron acceptor when molecular ...
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<p>Toxicity and serum metabolomics investigation of Mn-doped ZnS quantum dots in mice</p>
... Methods: In the present study, the toxicity and non-targeted metabolomics of Mn-doped ZnS QDs were investigated after single intravenous injection. Serum metabolites were evaluated based on gas chromatography – mass ...
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Studies on the Metabolism of Locust Fat Body
... They showed that a number of enzymes associated with the tricarboxylic acid cycle were present, namely, aconitase, wo-citric dehydrogenase, fumarase, malic dehydrogenase and cytochrome o[r] ...
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Metabolome- and genome-scale model analyses for engineering of Aureobasidium pullulans to enhance polymalic acid and malic acid production from sugarcane molasses
... Results: In this study, the production of PMA and MA from sucrose and sugarcane molasses by A. pullulans was studied in shake flasks and bioreactors. Comparative metabolome analysis of sucrose- and glucose-based ...
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