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Trigeminal Ganglion

Brn3a regulates neuronal subtype specification in the trigeminal ganglion by promoting Runx expression during sensory differentiation

Brn3a regulates neuronal subtype specification in the trigeminal ganglion by promoting Runx expression during sensory differentiation

... The transcription factor Brn3a, product of the pou4f1 gene, is expressed in most sensory neurons throughout embryogenesis. Prior work has demonstrated a role for Brn3a in the repression of early neurogenic genes; here we ...

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Inflammatory infiltration of the trigeminal ganglion after herpes simplex virus type 1 corneal infection.

Inflammatory infiltration of the trigeminal ganglion after herpes simplex virus type 1 corneal infection.

... Herpes simplex virus type 1 (HSV-1) corneal infection in the mouse initiates a series of events that culminate within 1 to 2 weeks in a stable latent neuronal infection of the trigeminal ganglion (TG). ...

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Induction and Inhibition of Apoptosis by Pseudorabies Virus in the Trigeminal Ganglion during Acute Infection of Swine

Induction and Inhibition of Apoptosis by Pseudorabies Virus in the Trigeminal Ganglion during Acute Infection of Swine

... the trigeminal ganglion during acute infection of its natural ...the trigeminal ganglia were assessed ...infected trigeminal ganglionic neurons during acute infection of ...

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Neurogenic inflammation: a study of rat trigeminal ganglion

Neurogenic inflammation: a study of rat trigeminal ganglion

... The trigeminal ganglion (TG) contains three main cell types: neurons, satellite glial cells (SGC) and Schwann cells; the first two have before been studied in vitro ...

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Kynurenic acid modulates experimentally induced inflammation in the trigeminal ganglion

Kynurenic acid modulates experimentally induced inflammation in the trigeminal ganglion

... AMPA: Amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid; BBB: Blood – brain barrier; CaMKII: Calcium calmodulin-dependent protein kinase II; CFA: Complete Freund ’ s adjuvant; CGRP: Calcitonin gene-related peptide; CLR: ...

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Chemokine CXCL13 mediates orofacial neuropathic pain via CXCR5/ERK pathway in the trigeminal ganglion of mice

Chemokine CXCL13 mediates orofacial neuropathic pain via CXCR5/ERK pathway in the trigeminal ganglion of mice

... in mechanisms of neuroinflammation is attributed to in- flammatory mediators, including proinflammatory cytokines and chemokines, which augment the nociceptive signals at different anatomical locations, including ...

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Original Article Delayed but not loss of gliogenesis in Rbpj- deficient trigeminal ganglion

Original Article Delayed but not loss of gliogenesis in Rbpj- deficient trigeminal ganglion

... root ganglion (DRG) and trigeminal ganglion (TG) are derived from a common pool of neural crest stem cells (NCCs), and are good systems to study the mechanisms of neurogenesis and ...

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Stereotactic Radiofrequency Ablation of Trigeminal Ganglion with Intraoperative CT Scans and under General Anesthesia

Stereotactic Radiofrequency Ablation of Trigeminal Ganglion with Intraoperative CT Scans and under General Anesthesia

... the trigeminal ganglion is performed using fluoroscopy and under heavy ...the trigeminal ganglion until its tip was 5 mm anterior to the clival ...Conclusion: Trigeminal ganglion ...

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Reactivation of Herpes Simplex Virus Type 1 in the Mouse Trigeminal Ganglion: an In Vivo Study of Virus Antigen and Cytokines

Reactivation of Herpes Simplex Virus Type 1 in the Mouse Trigeminal Ganglion: an In Vivo Study of Virus Antigen and Cytokines

... the trigeminal ganglion (TG), only small numbers of virus antigen-positive neurons have been identified, and only small amounts of infectious virus were detected (16, ...

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Trigeminal Ganglion and its Divisions: Detailed Anatomic MR Imaging with Contrast Enhanced 3D Constructive Interference in the Steady State Sequences

Trigeminal Ganglion and its Divisions: Detailed Anatomic MR Imaging with Contrast Enhanced 3D Constructive Interference in the Steady State Sequences

... cave. Trigeminal ganglion (thick white arrow) is at the anteroinferior border of the ...ing ganglion is clearly distinguished from the less-enhancing dura (white arrowhead) of the ...the ...

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Macrophages in trigeminal ganglion contribute to ectopic mechanical hypersensitivity following inferior alveolar nerve injury in rats

Macrophages in trigeminal ganglion contribute to ectopic mechanical hypersensitivity following inferior alveolar nerve injury in rats

... intra-trigeminal ganglion (TG) signal- ing mechanisms following trigeminal nerve injury are involved in the development of ectopic orofacial neuropathic ...root ganglion neu- rons and ...

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MR Imaging of the Trigeminal Ganglion, Nerve, and the Perineural Vascular Plexus: Normal Appearance and Variants with Correlation to Cadaver Specimens

MR Imaging of the Trigeminal Ganglion, Nerve, and the Perineural Vascular Plexus: Normal Appearance and Variants with Correlation to Cadaver Specimens

... the trigeminal ganglion and its branches, are crucial for evaluation of patients with suspected trigeminal nerve disease such as perineural tumor spread of skin cancer, which is most commonly seen ...

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Dural administration of inflammatory soup or Complete Freund’s Adjuvant induces activation and inflammatory response in the rat trigeminal ganglion

Dural administration of inflammatory soup or Complete Freund’s Adjuvant induces activation and inflammatory response in the rat trigeminal ganglion

... In our model, we observe activation of the trigeminal ganglion using the inflammatory substances CFA and IS. Based on the vascular theory of migraine, we wanted to see if the agents caused vasodilation or ...

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Prevalence of Varicella-Zoster Virus DNA in Dissociated Human Trigeminal Ganglion Neurons and Nonneuronal Cells

Prevalence of Varicella-Zoster Virus DNA in Dissociated Human Trigeminal Ganglion Neurons and Nonneuronal Cells

... FIG. 1. Cell-type separation of dissociated human TG. (A) Large debris from a trigeminal ganglion captured by 70-␮m mesh. (B) Flowthrough from 70-␮m mesh contains neuronal and nonneuronal cells, including ...

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Establishment of a novel therapeutic vector targeting the trigeminal ganglion in rats

Establishment of a novel therapeutic vector targeting the trigeminal ganglion in rats

... Background: In the pathogenesis of herpes simplex keratitis, herpes simplex virus type 1 (HSV-1) infection begins in corneal epithelium cells and then progresses through the sensory nerve endings and finally travels up ...

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Substance-P of neural cells in human trigeminal ganglion

Substance-P of neural cells in human trigeminal ganglion

... the trigeminal ganglion have been confirmed by results of experiments with double com- pound methods: axonal transport and immunohis- tochemistry ...human trigeminal ganglia identi- fied two ...

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Fewer Latent Herpes Simplex Virus Type 1 and Cytotoxic T Cells Occur in the Ophthalmic Division than in the Maxillary and Mandibular Divisions of the Human Trigeminal Ganglion and Nerve

Fewer Latent Herpes Simplex Virus Type 1 and Cytotoxic T Cells Occur in the Ophthalmic Division than in the Maxillary and Mandibular Divisions of the Human Trigeminal Ganglion and Nerve

... Herpes simplex virus type 1 (HSV-1) is a double-stranded DNA virus that usually infects the vast majority of the human population before and during adolescence. Primary HSV-1 infection is in general either asymptomatic ...

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LOCALIZATION OF CONNEXIN 36 AND CALCITONIN GENE RELATED PEPTIDE AS A DETERMINANT OF NEUROPATHIC PAIN IN THE TRIGEMINAL GANGLION

LOCALIZATION OF CONNEXIN 36 AND CALCITONIN GENE RELATED PEPTIDE AS A DETERMINANT OF NEUROPATHIC PAIN IN THE TRIGEMINAL GANGLION

... the trigeminal ganglion, can cause excitation of surrounding neuronal and satellite glial cells by paracrine signal and may further increase the synthesis release of CGRP 19 ...of trigeminal ...

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Modulation of inflammatory mediators in the trigeminal ganglion by botulinum neurotoxin type A: an organ culture study

Modulation of inflammatory mediators in the trigeminal ganglion by botulinum neurotoxin type A: an organ culture study

... The aim of the present study was designed to ask if BoNT-A can interact directly on sensory mechanisms in the trigeminal ganglion (TG) using an organ cul- ture method [14–16]. With this method we can study ...

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Sensory nerves in the human cerebral circulation and trigeminal ganglion: role in primary headaches

Sensory nerves in the human cerebral circulation and trigeminal ganglion: role in primary headaches

... the trigeminal ganglion is the only source for the CGRP-containing cerebrovascular innervation [2, 13, ...sensory ganglion cells, although the number of CGRP-containing cells exceeds the number of ...

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